Efecto del consumo de linaza en el perfil lipídico, el control del cáncer y como terapia de reemplazo hormonal en la menopausia: una revisión sistemática de ensayos clínicos aleatorizados

  • Catalina María Arango Alzate Universidad de Antioquia
  • Carlos Federico Molina Castaño Universidad de Antioquia
  • Berta Lucia Gaviria Gómez Universidad de Antioquia
  • Adriana Marcela Ruiz Pineda Universidad de Antioquia
  • Beatriz Estella López Marín Universidad de Antioquia
Palabras clave: linaza, enfermedades crónicas-prevención y control, terapia de reemplazo hormonal, lípidos, hiperlipidemias, menopausia, neoplasias de la mama-prevención y control, metanálisis, ensayo clínico controlado aleatorio

Resumen

Objetivo: evaluar los efectos del consumo de linaza sobre el perfil lipídico, control del cáncer y como reemplazo hormonal en la menopausia y en la andropausia. Materiales y métodos: se realizó una revisión sistemática de ensayos clínicos aleatorizados que examinaron los efectos del consumo delinaza sobre el peso corporal, la concentración de lípidos sanguíneos, el control del cáncer y los síntomas menopáusicos, usando las bases de datos de PubMed, Lilacs, OPS, OMS y Cochrane, publicados entre el 1 de enero de 2000 y el 30 de junio de 2010. A los artículos que cumplieron con criterios de inclusión se les evaluó su calidad metodológica. Resultados: fueron incluidos 49 artículos.Los estudios reportan que el consumo de linaza genera pequeños cambios en la concentración de los lípidos sanguíneos, mejora la sintomatología en mujeres menopáusicas, promueve la reducción de índices de proliferación tumoral y el aumento de apoptosis en cáncer de mama y próstata. Conclusiones: los resultados aún no son suficientes para recomendar el uso de la linaza para elcontrol de la hipercolesterolemia en pacientes dislipidémicos. La evidencia favorece la linaza como una alternativa en la terapia coadyuvante del tratamiento del cáncer de mama y de próstata, y en la reducción de síntomas durante la menopausia.
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Biografía del autor/a

Catalina María Arango Alzate, Universidad de Antioquia
Grupo de Investigación en Epidemiología. Facultad Nacional de Salud Pública, Universidad de Antioquia. Medellín-Colombia.
Carlos Federico Molina Castaño, Universidad de Antioquia
Grupo de Investigación en Epidemiología. Facultad Nacional de Salud Pública, Universidad de Antioquia. Medellín-Colombia.
Berta Lucia Gaviria Gómez, Universidad de Antioquia
Grupo de Investigación en Epidemiología. Facultad Nacional de Salud Pública, Universidad de Antioquia. Medellín-Colombia.
Adriana Marcela Ruiz Pineda, Universidad de Antioquia
Escuela de Nutrición y Dietética, Universidad de Antioquia. Medellín-Colombia.
Beatriz Estella López Marín, Universidad de Antioquia
Escuela de Nutrición y Dietética, Universidad de Antioquia. Medellín-Colombia.

Citas

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Publicado
2011-09-18
Cómo citar
Arango Alzate, C. M., Molina Castaño, C. F., Gaviria Gómez, B. L., Ruiz Pineda, A. M., & López Marín, B. E. (2011). Efecto del consumo de linaza en el perfil lipídico, el control del cáncer y como terapia de reemplazo hormonal en la menopausia: una revisión sistemática de ensayos clínicos aleatorizados. Perspectivas En Nutrición Humana, 13(1), 73-91. Recuperado a partir de https://revistas.udea.edu.co/index.php/nutricion/article/view/10171
Sección
Artículos de Revisión