Asociación entre las diferentes entidades clínicas, el leucograma y la presencia de bandas neutrófilas en pacientes hospitalizados en la Clínica León XIII, Medellín, Colombia

Patricia Jaramillo; Jorge Llanos; Jhonatan Restrepo; Manuela Mesa; Astrid Escobar; Julia Urrea

doi:10.17533/udea.hm.335198

Authors

Patricia Jaramillo University of Antioquia
Jorge Llanos University of Antioquia
Jhonatan Restrepo University of Antioquia
Manuela Mesa University of Antioquia
Astrid Escobar León XIII Clinic
Julia Urrea León XIII Clinic

DOI:

https://doi.org/10.17533/udea.hm.335198

Keywords:

neutrophil bands, deviation to the left, peripheral blood smear, bacterial infection, leukogram

Abstract

Introduction: the presence of neutrophil bands in peripheral blood is widely used in clinical settings to support the diagnosis of patients with a suspected bacterial infection. However, the diagnostic accuracy of these cells’ relative counts, which is necessary for the diagnosis of bacterial infection, is limited due to low sensitivity.

Methods: a total of 242 hemograms of hospitalized patients in the León XIII Clinic were included. These patients presented left-sided alarms in the ADVIA®2120/2120i hematology equipment and increased neutrophil bands greater than 5% in the peripheral blood smear. Data about age, sex, microbiological results and levels of C-reactive protein of the patients was also gathered. The statistical analysis was performed in SPSS software, together with a Spearman correlation analysis and a Kruskal-Wallis H test.

Results: a high variability was observed in the relative count of the neutrophil bands in the different clinical entities. Nonetheless, a significant increase of these cells was found in other non-infectious diseases such as renal and pulmonary diseases with a median of 25 and 22.5 respectively, above bacterial infections with a median of 19 cells.

Conclusions: the increase of the neutrophil bands was not related to any particular pathology, which is why its diagnostic value has little use to be correlated with a bacterial infection exclusively.

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Author Biographies

Patricia Jaramillo, University of Antioquia

Bacteriologist, Hematology Specialist. MSc. in Microbiology, with emphasis in Hematology. Professor at the School of Microbiology, University of Antioquia. Molecular Hematopathology Research Group (HEMO), University of Antioquia. University IPS - León XIII Clinic.

Jorge Llanos, University of Antioquia

Microbiologist and Bioanalyst, University of Antioquia.

Astrid Escobar, León XIII Clinic

Bacteriologist, León XIII Clinic.

Julia Urrea, León XIII Clinic

Bacteriologist, Hematology Specialist, MSc. in Microbiology, León XIII Clinic.

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