El sistema CRISPR-Cas y su aplicación en las enfermedades infecciosas
DOI:
https://doi.org/10.17533/udea.hm.339115Downloads
Referências
Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, et al. An updated evolutionary clas-sification of CRISPR-Cas systems. Nat Rev Micro-biol. 2015;13:722-736.
Koonin EV, Makarova KS, Zhang F. Diversity, classifi-cation and evolution of CRISPR-Cas systems. Curr Opin Microbiol. 2017;37:67-78.
Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, et al. CRISPR provides acquired resis- tance against viruses in prokaryotes. Science. 2007;315:1709-1712.
Gasiunas G, Barrangou R, Horvath P, Siksnys V.Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive im- munity in bacteria. Proc Natl Acad Sci. 2012;109:E2579-E2586.
Müller V, Rajer F, Frykholm K, Nyberg LK, Quaderi S, Fritzsche J, et al. Direct identification of antibi-otic resistance genes on single plasmid molecules using CRISPR/Cas9 in combination with optical DNA mapping. Sci Rep. 2016;1;6:37938.
Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F. Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6. Science. 2018;360(6387):439-444.
Hu W, Kaminski R, Yang F, Zhang Y, Cosentino L, Li F, et al. RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection. Proc Natl Acad Sci. 2014;111(31):11461-6.