Single cell sequencing technologies as a source of knowledge to understand more about cellular heterogeneity in different biological contexts and the challenges from our region.
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Tang F, Barbacioru C, Wang Y, Nordman E, Lee C, Xu N, et al. mRNA-Seq whole-transcriptome analysis of a single cell. Nat Methods. 2009; 6(5):377-82. doi: 10.1038/nmeth.1315
Luecken MD, Theis FJ. Current best practices in single-cell RNA-seq analysis: a tutorial. Mol Syst Biol. 2019;15(6):e8746. doi: 10.15252/msb.20188746.
Rood JE, Maartens A, Hupalowska A, Teichmann SA, Regev A. Impact of the Human Cell Atlas on medicine. Nat Med. 2022; 28(12):2486-2496. doi: 10.1038/s41591-022-02104-7.
Baysoy A, Bai Z, Satija R, Fan R. The technological landscape and applications of single-cell multi-omics. Nat Rev Mol Cell Biol. 2023; 24(10):695-713. Doi: 10.1038/s41580-023-00615-w.
Wilkinson MD, Dumontier M, Aalbersberg IJ, Appleton G, Axton M, Baak A, et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci Data. 2016; 3:160018. doi: 10.1038/sdata.2016.18.
CZI Single-Cell Biology Program, Shibla Abdulla, Brian Aevermann, Pedro Assis, Seve Badajoz, Sidney M. Bell, et al. CZ CELL×GENE Discover: A single-cell data platform for scalable exploration, analysis and modeling of aggregated data. bioRxiv 2023.10.30.563174; doi: https://doi.org/10.1101/2023.10.30.563174
Tarhan L, Bistline J, Chang J, Galloway B, Hanna E, Weitz E. Single Cell Portal: an interactive home for single-cell genomics data. bioRxiv. 2023; 2023.07.13.548886. doi: 10.1101/2023.07.13.548886.
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, et al. Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP). Nat Cell Biol. 2023;25(8):1089-1100. doi: 10.1038/s41556-023-01194-w.
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, et al. The Human Cell Atlas. Elife. 2017;6:e27041. doi: 10.7554/eLife.27041.
George N, Fexova S, Fuentes AM, Madrigal P, Bi Y, Iqbal H, et al. Expression Atlas update: insights from sequencing data at both bulk and single cell level. Nucleic Acids Res. 2024; 52(D1):D107-D114. doi: 10.1093/nar/gkad1021.
Howick VM, Russell AJC, Andrews T, Heaton H, Reid AJ, Natarajan K, et al. The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle. Science. 2019;365(6455):eaaw2619. doi: 10.1126/science.aaw2619.
Franzén O, Gan LM, Björkegren JLM. PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data. Database (Oxford). 2019; 2019:baz046. doi: 10.1093/database/baz046.
Catta-Preta CMC, Ghosh K, Sacks DL, Ferreira TR. Single-cell atlas of Leishmania development in sandflies reveals the heterogeneity of transmitted parasites and their role in infection. Proc Natl Acad Sci U S A. 2024; 121(52):e2406776121. doi: 10.1073/pnas.2406776121
Homberger C, Barquist L, Vogel J. Ushering in a new era of single-cell transcriptomics in bacteria. Microlife. 2022; 3:uqac020. doi: 10.1093/femsml/uqac020.
Gioacchino E, Vandelannoote K, Ruberto AA, Popovici J, Cantaert T. Unraveling the intricacies of host-pathogen interaction through single-cell genomics. Microbes Infect. 2024; 26(7):105313. doi: 10.1016/j.micinf.2024.105313.
Cerny O, Godlee C, Lobato-Márquez D. Editorial: Single cell analysis of bacteria-host interaction. Front Cell Infect Microbiol. 2023; 13:1196905. doi: 10.3389/fcimb.2023.1196905.
Franco-Paredes C, Jones D, Rodríguez-Morales AJ, Santos-Preciado JI. Commentary: improving the health of neglected populations in Latin America. BMC Public Health. 2007; 7, 11. https://doi.org/10.1186/1471-2458-7-11
Marmot, M. Social determinants of health inequalities. The lancet. 2005; 365(9464): 1099-1104.
Folch E, Hernandez I, Barragan M, Franco-Paredes C. Infectious diseases, non-zero-sum thinking, and the developing world. Am J Med Sci. 2003;326(2):66-72. doi: 10.1097/00000441-200308000-00003.
Farmer PE, Furin JJ, Katz JT. Global health equity. Lancet. 2004; 363(9423):1832. doi: 10.1016/S0140-6736(04)16325-3.
Trouiller P, Olliaro P, Torreele E, Orbinski J, Laing R, Ford N. Drug development for neglected diseases: a deficient market and a public-health policy failure. Lancet. 2002; 359(9324):2188-94. doi: 10.1016/S0140-6736(02)09096-7.
Norris ET, Wang L, Conley AB, Rishishwar L, Mariño-Ramírez L, Valderrama-Aguirre A, et al. Genetic ancestry, admixture and health determinants in Latin America. BMC genomics. 2018; 19(S8): 861. https://doi.org/10.1186/s12864-018-5195-7
Cuesta-Astroz Y, Santos A, Oliveira G, Jensen LJ. Analysis of Predicted Host-Parasite Interactomes Reveals Commonalities and Specificities Related to Parasitic Lifestyle and Tissues Tropism. Front Immunol. 2019; 10:212. doi: 10.3389/fimmu.2019.00212.
Chattopadhyay PK, Roederer M, Bolton DL. A deadly dance: the choreography of host-pathogen interactions, as revealed by single-cell technologies. Nat Commun. 2018; 9(1):4638. doi: 10.1038/s41467-018-06214-0.
Couto-Silva CM, Nunes K, Venturini G, Araújo Castro E, Silva M, Pereira LV, et al. Indigenous people from Amazon show genetic signatures of pathogen-driven selection. Science advances. 2023; 9(10), eabo0234. doi.org/10.1126/sciadv.abo0234
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