Novas vias de permeabilidade em Plasmodium falciparum: considerações como alvo farmacológico e avanços em inibidores potenciais
DOI:
https://doi.org/10.17533/udea.acbi.v43n115a03Palavras-chave:
NPP, Plasmodium, malaria, antimaláricos, eritrocitoResumo
Na malária, a resistência persistente aos antimaláricos pelo Plasmodium falciparum constitui um problema de saúde pública mundial. As Novas Vias de Permeabilidade (NPP) são um alvo terapêutico promissor, pois o parasita as utiliza para modificar a membrana do eritrócito e torná-lo permeável a vários nutrientes necessários ao seu crescimento. Apresentamos uma revisão temática onde foi feita uma compilação de vários estudos relacionados ao NPP, sua importância e seus inibidores.
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