Histiocitosis sistémica maligna en un canino. Reporte de un caso


  • Julieta E. Ochoa Amaya
  • Anita Roque Rodríguez
  • Natalia Pedraza Castillo




canine, malignant systemic histiocytose,, pyometra



The malignant systemic histiocytoses is a disease slightly common of dogs and cats, that has been characterize by the neoplasic proliferation of macrofhages in different organs and systems. The proliferative histiocytic disease can present nodular masses in lungs, liver, and lymphatic mediastines nodules, the dermis and epidermis are not very compromised. To the Veterinary Clinic of the Universidad de los Llanos arrived a female canine of 5 years old with depression, lack of appetite, abdominal distension, hyperventilation, purulent secretion by the vulva. With the necropsy was found a circular, multilobuled, hard, hemorrhagic mass with a diameter of 6 cm located in the cranial mediastine; in the abdominal cavity, metastases of the neoplasm to the liver and spleen. In the uterus was noticed a greater purulent secretion in the left horn. By histopathology the diagnostic was a Malignant Systemic Histiocytoses, the lungs, liver, lymph nodes and arm were affected. In the uterus was diagnosticing a pyometra.


= 206 veces | PDF
= 25 veces|


Download data is not yet available.


Affolter VK y Moore PF. Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. Vet Pathol 2002; 39:74-83.

Banks WJ. Histología veterinaria aplicada. 2nd ed. México: Editorial Manual moderno; 1996.

Barberá JF. Histiocitosis. Protocolos diagnósticos y terapéuticos en dermatología pediátrica. 2005; 159-165.

Borrego L, Carretero G, Domínguez JM, Hernández B, Hernández JA, et . al . Curso dermatología y venereología. Dep de ciencias med y quir. 1997; 1:6

Carlyle T, Duncan R, KIng N. Veterinary Pathology. 6a ed. USA: lippincott wilims & wilkins; 1996.

Cotran R, Kumar D, Robbins S. Pathologic basis of disease. 5 ed. W.B Saunders company; 1994.

Cowell R. The Veterinary Clinics of North America. Small animal practice Cytology part II. Ed. Saunders company; january 2003; 33,1: 28,

Ettinger S. Feldman E. Tex book of Veterinary internal medicine. Philadelphia: Saunders 1999.

Herrero-Hernández A, Ramírez-Jiménez S, García-Martín F, Martínez-Valverde A. Síndromes hemofagocíticos. An Esp Pediatr 1998; 49: 230-236.

Jubb, Kennedy, Palmer’s. Pathology of Domestic Animals. Neoplastic and reactive diseases of the skin and mammary glands. Elsevier Saunders, vol 1 P 769 – 770, 2007.

Kiran MM, Karaman M, Hatipoglu F, Koc Y. Malignant fibrous histiocytoma in a dog: a case report. Vet. Med. – Czech 2005 ;50: 553–557.

Latimer K, Mahaffey E, Prasse K. Veterinary Laboratory medicine. 4 ed. A Blackwell Publishing company; 2003.

Mcgavin D, Carlton W, Zachary J. Thomson ́s. Special Veterinary Pathology. 3ª Ed. USA: Mosby, Inc. An Affiliate of Elsevier; 2001.

Meuten DJ. .Tumors in domestic Animals, 4 Ed Iowa: Iowa State. 2002; 90: 233-237.

Miller M, Ramos-Vara J. Mesenchymal Neoplasms and Tumor-like lesions in the Skin of Domestic Species. Memorias del “I Curso Seminario Internacional de Patología Veterinaria”. Universidad Nacional de Colombia Bogota D. C., 13 al 15 de agosto de 2008.

Morris J, Mcinnes E, Bostock D, Hoather T, Dobson J. Immunohistochemical and histopathologic features of 14 malignant fibrous histiocytomas from Flat-Coated Retrievers. Vet Pathol 2002; 39: 473–479.

Olsen K. Malignant histiocytosis in a cat. Cornell University college of Vet Med. 2003.

Revajova V, Levkut M, Kozak M, Bilek J, Magic D, et al . Canine histiocytic syndrome manifested as ulcerative gastroenterocolitis, skin lesions and lymphadenopathy a case report. Vet. Med. Czech , 2004; 8: 312–316.

Tillaart M. Malignant histiocytosis in dogs. Shelley’s Histio Homepage. 2006.

Valli E, Jacobs R, Parodi A, Vernau W, Moore P. Histologycal Classification of Hematopoyetic Tumors of Domestic Animals. Vol. VIII. Washington, D. C: .Armed Forces Institute of Pathology; 2002.

Willard M, Tvedten H. Small animal clinical diagnosis by laboratory methods. 4 ed. Saunders. Elsevier. 2004.




How to Cite

Ochoa Amaya, J. E., Roque Rodríguez, A., & Pedraza Castillo, N. (2009). Histiocitosis sistémica maligna en un canino. Reporte de un caso. Revista Colombiana De Ciencias Pecuarias, 22(1), 13. https://doi.org/10.17533/udea.rccp.324351



Clinical cases

Most read articles by the same author(s)

Similar Articles

> >> 

You may also start an advanced similarity search for this article.