Effect of Educational Interventions to Reduce Readmissions due to Heart Failure Decompensation in Adults: a Systematic Review and Meta-analysis
DOI:
https://doi.org/10.17533/udea.iee.v39n2e05Keywords:
heart failure, patient readmission, patient education as topic, self-care, systematic reviewAbstract
Objective. To estimate the combined effect of educational interventions (EI) on decreased readmissions and time of hospital stay in adults with heart failure, compared with usual care.
Methods. Systematic review (SR) and meta-analysis (MA) of randomized controlled trials that followed the recommendations of the PRISMA statement. The protocol was registered on PROSPERO (CRD42019139321). Searches were made from inception until July 2019 in the databases of PubMed/Medline, Embase, Cochrane CENTRAL, Lilacs, Web of Science, and Scopus. The MA was conducted through the random effects model. The effect measure used for the dichotomous outcomes was relative risk (RR) and for continuous outcomes the mean difference (MD) was used, with 95% confidence intervals (CI). Heterogeneity was evaluated through the inconsistency statistic (I2).
Results. Of 2369 studies identified, 45 were included in the SR and 43 in the MA. The MA of studies with follow-up at six months showed a decrease in readmissions of 30% (RR: 0.70; 95% CI: 0.58 to 0.84; I2: 0%) and the 12-month follow-up evidenced a reduction of 33% (RR: 0.67; 95% CI: 0.58 to 0.76; I2: 52%); both analyses in favor of the EI group. Regarding the time of hospital stay, a reduction was found of approximately two days in patients who received the EI (MD: -1.98; 95% CI: -3.27 to -0.69; I2: 7%).
Conclusion. The findings support the benefits of EI to reduce readmissions and days of hospital stay in adult patients with heart failure.
Downloads
References
Imizcoz MÁ. Insuficiencia cardíaca. Definición, fisiopatología y cambios estructurales. Cir. Cardiov. 2008;15(1):15–20.
Pons F, Lupón J, Urrutia A, González B, Crespo E, Díez C, et al. Mortalidad y causas de muerte en pacientes con insuficiencia cardiaca: experiencia de una unidad especializada multidisciplinaria. Rev. Esp. Cardiol. 2010; 63(3):303–14.
Gómez E. Capítulo 2. Introducción, epidemiología de la falla cardiaca e historia de las clínicas de falla cardiaca en Colombia. Rev. Colomb. Cardiol. 2016;23(Suppl 1):6–12.
Caballero A, Pinilla MI, Mendoza ICS, Peña JRA. Frecuencia de reingresos hospitalarios y factores asociados en afiliados a una administradora de servicios de salud en Colombia. Cad. Saúde Pública. 2016; 32(7):e00146014.
Farmakis D, Papingiotis G, Parissis J. Acute heart failure: Epidemiology and socioeconomic burden. Contin. Cardiol. Educ. 2017; 3(3):88–92.
Augustovski F, Caporale J, Fosco M, Alcaraz A, Diez M, Thierer J, et al. Uso de recursos y costos de hospitalizaciones por insuficiencia cardíaca: un estudio retrospectivo multicéntrico en Argentina. Value Health Reg. Issues. 2017; 14:73–80.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med. 2009; 6(7):e1000097.
Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page M, et al. Cochrane Handbook for Systematic Reviews of Interventions version 6.2. 2021 [cited 2021 Jan 11]. Available from: https://training.cochrane.org/cochrane-handbook-systematic-reviews-interventions
Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011; 343:d5928.
Aldamiz‐Echevarria B, Muñiz J, Rodríguez‐Fernández JA, Vidan‐Martinez L, Silva‐Cesar M, Lamelo‐Alfonsin F, et al. Ensayo clínico aleatorizado y controlado para valorar una intervención por una unidad de hospitalización domiciliaria en la reducción de reingresos y muerte en pacientes dados de alta del hospital tras un ingreso por insuficiencia cardiaca. Rev. Esp. Cardiol. 2007; 60(9):914–22.
Atienza F, Anguita M, Martinez-Alzamora N, Osca J, Ojeda S, Almenar L, et al. Multicenter randomized trial of a comprehensive hospital discharge and outpatient heart failure management program. Eur. J. Heart Fail. 2004; 6(5):643–52.
Blue L, Lang E, McMurray JJ, Davie AP, McDonagh TA, Murdoch DR, et al. Randomised controlled trial of specialist nurse intervention in heart failure. BMJ. 2001; 323(7315):715–8.
Boyde M, Peters R, New N, Hwang R, Ha T, Korczyk D. Self-care educational intervention to reduce hospitalisations in heart failure: A randomised controlled trial. Eur. J. Cardiovasc. Nurs. 2018; 17(2):178–85.
Jack BW, Chetty VK, Anthony D, Greenwald JL, Sanchez GM, Johnson AE, et al. A reengineered hospital discharge program to decrease rehospitalization. Ann. Intern. Med. 2009; 150(3):178–87.
Brotons C, Falces C, Alegre J, Ballarín E, Casanovas J, Catà T, et al. Ensayo clínico aleatorizado para evaluar la efectividad de una intervención domiciliaria en pacientes con insuficiencia cardiaca: estudio IC-DOM. Rev. Esp. Cardiol. 2009; 62(4):400–8.
Cañon-Montañez W, Oróstegui-Arenas M. Intervenciones educativas de enfermería en pacientes ambulatorios con falla cardiaca. Enferm. Glob. 2013; 12(31):52–67.
Cui X, Zhou X, Ma L, Sun T, Bishop L, Gardiner FW, et al. A nurse-led structured education program improves self-management skills and reduces hospital readmissions in patients with chronic heart failure: a randomized and controlled trial in China. Rural Remote Health. 2019; 19(2):5270.
Davis KK, Mintzer M, Dennison Himmelfarb CR, Hayat MJ, Rotman S, Allen J. Targeted intervention improves knowledge but not self-care or readmissions in heart failure patients with mild cognitive impairment. Eur. J. Heart Fail. 2012; 14(9):1041–9.
De Souza EN, Rohde LE, Ruschel KB, Mussi CM, Da-Silva L, Biolo A, et al. A nurse-based strategy reduces heart failure morbidity in patients admitted for acute decompensated heart failure in Brazil: The HELEN-II clinical trial. Eur. J. Heart Fail. 2014; 16(9):1002–8.
DeBusk RF, Miller NH, Parker KM, Bandura A, Kraemer HC, Cher DJ, et al. Care management for low-risk patients with heart failure: A randomized, controlled trial. Ann. Intern. Med. 2004; 141(8):606–13.
Delaney C, Apostolidis B, Bartos S, Morrison H, Smith L, Fortinsky R. A Randomized Trial of Telemonitoring and Self-Care Education in Heart Failure Patients Following Home Care Discharge. Home Health Care Manag. Pract. 2013; 25(5):187–95.
DeWalt DA, Malone RM, Bryant ME, Kosnar MC, Corr KE, Rothman RL, et al. A heart failure self-management program for patients of all literacy levels: A randomized, controlled trial [ISRCTN11535170]. BMC Health Serv Res. 2006; 6:30.
Domingues FB, Clausell N, Aliti GB, Dominguez DR, Rabelo ER. Education and telephone monitoring by nurses of patients with heart failure: randomized clinical trial. Arq. Bras. Cardiol. 2011; 96(3):233–9.
Doughty RN, Wright SP, Pearl A, Walsh HJ, Muncaster S, Whalley GA, et al. Randomized, controlled trial of integrated heart failure management: The Auckland Heart Failure Management Study. Eur. Heart J. 2002; 23(2):139–46.
Dracup K, Moser DK, Pelter MM, Nesbitt TS, Southard J, Paul SM, et al. Randomized, controlled trial to improve self-care in patients with heart failure living in rural areas. Circulation. 2014; 130(3):256–64.
Ducharme A, Doyon O, White M, Rouleau JL, Brophy JM. Impact of care at a multidisciplinary congestive heart failure clinic: a randomized trial. CMAJ. 2005; 173(1):40–5.
Gámez-López AL, Bonilla-Palomas JL, Anguita-Sánchez M, Castillo-Domínguez JC, Arizón del Prado JM, Suárez de Lezo J. Efectos sobre la mortalidad y reingresos hospitalarios de tres tipos distintos de programas de intervención en pacientes hospitalizados por insuficiencia cardiaca: ensayo clínico aleatorizado. Med. Clin (Barc). 2012; 138(5):192–8.
González-Guerrero JL, Alonso-Fernández T, García-Mayolín N, Gusi N, Ribera-Casado JM. Effectiveness of a follow-up program for elderly heart failure patients after hospital discharge. A randomized controlled trial. Eur. Geriatr. Med. 2014; 5(4):252–7.
Hägglund E, Lyngå P, Frie F, Ullman B, Persson H, Melin M, et al. Patient-centred home-based management of heart failure: Findings from a randomised clinical trial evaluating a tablet computer for self-care, quality of life and effects on knowledge. Scand. Cardiovasc. J. 2015; 49(4):193–9.
Holland R, Brooksby I, Lenaghan E, Ashton K, Hay L, Smith R, et al. Effectiveness of visits from community pharmacists for patients with heart failure: HeartMed randomised controlled trial. BMJ. 2007; 334(7603):1098.
Jaarsma T, Halfens R, Abu-Saad HH, Dracup K, Gorgels T, van Ree J, et al. Effects of education and support on self-care and resource utilization in patients with heart failure. Eur. Heart J. 1999; 20(9):673–82.
Jaarsma T, Wal MH, Lesman‐Leegte I, Luttik ML, Hogenhuis J, Veeger NJ et al. Effect of moderate or intensive disease management program on outcome in patients with heart failure: Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure (COACH). Arch. Intern. Med. 2008; 168(3):316–24.
Jerant AF, Azari R, Nesbitt TS. Reducing the cost of frequent hospital admissions for congestive heart failure: a randomized trial of a home telecare intervention. Med. Care. 2001; 39(11):1234–45.
Kato NP, Kinugawa K, Sano M, Kogure A, Sakuragi F, Kobukata K, et al. How effective is an in-hospital heart failure self-care program in a Japanese setting? Lessons from a randomized controlled pilot study. Patient Prefer. Adherence. 2016; 10:171–81.
Kimmelstiel C, Levine D, Perry K, Patel AR, Sadaniantz A, Gorham N, et al. Randomized, controlled evaluation of short- and long-term benefits of heart failure disease management within a diverse provider network: The SPAN-CHF trial. Circulation. 2004; 110(11):1450–5.
Koelling TM, Johnson ML, Cody RJ, Aaronson KD. Discharge education improves clinical outcomes in patients with chronic heart failure. Circulation. 2005; 111(2):179–85.
Krumholz HM, Amatruda J, Smith GL, Mattera JA, Roumanis SA, Radford MJ, et al. Randomized trial of an education and support intervention to prevent readmission of patients with heart failure. J. Am. Coll. Cardiol. 2002; 39(1):83–9.
Leventhal ME, Denhaerynck K, Brunner-La Rocca HP, Burnand B, Conca-Zeller A, Bernasconi AT, et al. Swiss Interdisciplinary Management programme for Heart Failure (SWIM-HF): a randomised controlled trial study of an outpatient inter-professional management programme for heart failure patients in Switzerland. Swiss Med. Wkly. 2011; 141: w13171.
Mau MKLM, Lim E, Kaholokula JK, Loui TMU, Cheng Y, Seto TB. A randomized controlled trial to improve heart failure disparities: The Mālama Pu‘uwai (caring for heart) Study. Open Access J. Clin. Trials. 2017; 9:65–74.
Melin M, Hägglund E, Ullman B, Persson H, Hagerman I. Effects of a Tablet Computer on Self-care, Quality of Life, and Knowledge: A Randomized Clinical Trial. J. Cardiovasc. Nurs. 2018; 33(4):336–43.
Naylor MD, Brooten DA, Campbell RL, Maislin G, McCauley KM, Schwartz JS. Transitional care of older adults hospitalized with heart failure: a randomized, controlled trial. J. Am. Geriatr. Soc. 2004; 52(5):675–84.
Negarandeh R, Zolfaghari M, Bashi N, Kiarsi M. Evaluating the Effect of Monitoring through Telephone (Tele-Monitoring) on Self-Care Behaviors and Readmission of Patients with Heart Failure after Discharge. Appl. Clin. Inform. 2019; 10(2):261–8.
Otsu H, Moriyama M. Effectiveness of an educational self-management program for outpatients with chronic heart failure. Jpn. J. Nurs. Sci. 2011; 8(2):140–52.
Ramachandran K, Husain N, Maikhuri R, Seth S, Vij A, Kumar M, et al. Impact of a comprehensive telephone-based disease management programme on quality-of-life in patients with heart failure. Natl. Med. J. India. 2007; 20(2):67–73.
Rodríguez-Gázquez MA, Arredondo-Holguín E, Herrera-Cortés R. Efectividad de un programa educativo en enfermería en el autocuidado de los pacientes con insuficiencia cardíaca: ensayo clínico controlado. Rev. Latino-Am. Enfermagem. 2012; 20(2):296-306.
Ruschel KB, Rabelo-Silva ER, Rohde LE, de Souza EN, Mussi CM, Polanczyk CA. Cost-Effectiveness of a Home Visit Program for Patients with Heart Failure in Brazil: Evidence from a Randomized Clinical Trial. Value Health Reg. Issues. 2018; 17:81–7.
Sethares KA, Elliott K. The effect of a tailored message intervention on heart failure readmission rates, quality of life, and benefit and barrier beliefs in persons with heart failure. Heart Lung. 2004; 33(4):249–60.
Stewart S, Chan Y, Wong C, Jennings G, Scuffham P, Esterman A, et al. Impact of a nurse-led home and clinic-based secondary prevention programme to prevent progressive cardiac dysfunction in high-risk individuals: the Nurse-led Intervention for Less Chronic Heart Failure (NIL-CHF) randomized controlled study. Eur. J. Heart Fail. 2015; 17(6):620–30.
Tomita MR, Tsai B, Fisher NM, Kumar NA, Wilding G, Stanton K, et al. Effects of multidisciplinary internet-based program on management of heart failure. J. Multidiscip. Healthc. 2009; 2:13–21.
Tsuchihashi-Makaya M, Matsuo H, Kakinoki S, Takechi S, Kinugawa S, Tsutsui H, et al. Home-based disease management program to improve psychological status in patients with heart failure in Japan. Circ. J. 2013; 77(4):926–33.
Wakefield BJ, Ward MM, Holman JE, Ray A, Scherubel M, Burns TL, et al. Evaluation of home telehealth following hospitalization for heart failure: a randomized trial. Telemed. J. E. Health. 2008; 14(8):753–61.
Wierzchowiecki M, Poprawski K, Nowicka A, Kandziora M, Pia̧tkowska A, Jankowiak M, et al. A new programme of multidisciplinary care for patients with heart failure in Poznań: one-year follow-up. Kardiol Pol. 2006; 64(10):1063–70.
Wright SP, Walsh H, Ingley KM, Muncaster SA, Gamble GD, Pearl A, et al. Uptake of self-management strategies in a heart failure management programme. Eur. J. Heart Fail. 2003; 5(3):371–80.
Yu DSF, Lee DTF, Stewart S, Thompson DR, Choi K, Yu C. Effect of Nurse-Implemented Transitional Care for Chinese Individuals with Chronic Heart Failure in Hong Kong: A Randomized Controlled Trial. J. Am. Geriatr. Soc. 2015; 63(8):1583–93.
Rice H, Say R, Betihavas V. The effect of nurse-led education on hospitalisation, readmission, quality of life and cost in adults with heart failure. A systematic review. Patient Educ. Couns. 2018; 101(3):363–74.
Malik AH, Malik SS, Aronow WS. Effect of home-based follow-up intervention on readmissions and mortality in heart failure patients: a meta-analysis. Future Cardiol. 2019; 15(5):377–86.
Takeda A, Martin N, Taylor RS, Taylor S. Disease management interventions for heart failure. Cochrane Database Syst Rev. 2019; 1(1): CD002752.
Cañon-Montañez W, López de Ávila M, Rodríguez-Acelas AL. Programas de autocuidado y rol de la enfermería para mejorar los resultados clínicos en pacientes con insuficiencia cardiaca. Rev. Enf. Ref. 2020; V(3):1–6.
Cañon-Montañez W, Duque-Cartagena T, Rodríguez-Acelas AL. Intervenciones educativas para el manejo de la falla cardiaca: estrategias para mejorar los desenlaces clínicos de los pacientes. Av. Enferm. 2021; 39(1):7–10.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Investigación y Educación en Enfermería
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Derechos de propiedad / Direitos de Propriedade
English: If the article is accepted for publication, all copyright will be of exclusive property of Investigación y Educación en Enfermería. The text and the graphics included in the publication are exclusive responsibility of the authors and not necessarily reflect the thought of the Editorial Committee.
Español: Si el artículo es aprobado para publicación, todos los derechos son de propiedad de Investigación y Educación en Enfermería. El texto y las gráficas incluidas en la publicación son de exclusiva responsabilidad de los autores y no necesariamente refleja el pensamiento del Comité Editorial.
Português: Se o artigo for aceito para publicação, todos os direitos autorais serão de propriedade exclusiva de Investigación y Educación en Enfermería. O texto e os gráficos incluídos na publicação são de responsabilidade exclusiva dos autores e não refletem necessariamente o pensamento do Comitê Editorial.