Development of a photoirradiation system for photodynamic therapy with dosimetric control
DOI:
https://doi.org/10.17533/udea.redin.13538Keywords:
biomedical instrumentation, photodynamic therapy, phantoms, dosimetryAbstract
Photodynamic Therapy is a well know treatment based on light interaction with a photosensitizing drug, used in the treatment of certain diseases like cancer. In this issue, the development of asystem for superficial irradiation, which allows the application of Photodynamic Therapy at 630nm using a light emitting diode as a radiation source. It is proposed a control for the energy dose delivery in depth, which incorporates the calculations from a radiation distribution model. Also it is reported the construction and characterization of optical phantoms in aqueous suspensions, used for models’ verification and system performance testing.
Downloads
References
J. Moan, Q. Peng. “An outline of the hundred-year history of PDT”.Anticancer Res. Vol. 23. 2003.pp. 3591-600.
P. N. Prasad.Introduction to Biophotonics. Ed. John Wiley & Sons Inc. USA. 2003 pp. 237-243. DOI: https://doi.org/10.1002/0471465380
A. E. da Hora Machado. “Terapia fotodinâmica: princípios, potencial de aplicação e perspectivas”. Química Nova. Vol. 23. 2000. pp. 273-243. DOI: https://doi.org/10.1590/S0100-40422000000200015
M. H. Gold, M. P. Goldman. “5-Aminolevulinic Acid Photodynamic Therapy: Where We Have Been and Where We Are Going”.Dermatol. Surg.Vol. 30. 2004. pp. 1077-1084. DOI: https://doi.org/10.1111/j.1524-4725.2004.30331.x
T. S. Mang. “Dosimetric Concepts for PDT”. Photodiagnosis and Photodynamic Therapy.Vol. 5. 2008. pp. 217-223. DOI: https://doi.org/10.1016/j.pdpdt.2008.09.006
A. Juzeniene, P. Juzenas , Li-Wei Ma, V. Iani, J.Moan.“Effectiveness of different light sources for 5-ALA PDT”. Laser Med Sci. Vol. 19. 2004. pp. 139- 149 DOI: https://doi.org/10.1007/s10103-004-0314-x
AAPM Report No. 88. Photodynamic Therapy Dosimetry. American Association of Physicist in Medicine. USA. 2005. pp. 11-12.
B. W. Henderson, T. M. Busch, J. W. Snyder. “Fluence rate as a modulator of PDT mechanisms”. Lasers Surg. Med. Vol. 38. 2006. pp. 489-93. DOI: https://doi.org/10.1002/lsm.20327
B. C.Wilson, M. S.Patterson, “The physics, biophysics and technology of photodynamic therapy”. Phys. Med. Biol. Vol. 53. 2008. pp 61-109. DOI: https://doi.org/10.1088/0031-9155/53/9/R01
A. Ishimaru. “Diffusion Approximation”. Wave Propagation and scattering in random media, single scattering and transport theory. Vol. 1.Ed. Academic Press.USA. 1978.pp. 175-185. DOI: https://doi.org/10.1016/B978-0-12-374701-3.50015-6
J. L. Karagiannes, Z. Zhang, B. Grossweiner, L. I. Grossweiner. “Applications of the 1-D diffusion approximation to the optics of tissues and tissue phantoms”. Applied Optics. Vol. 28. 1989. pp. 2311- 2317. DOI: https://doi.org/10.1364/AO.28.002311
S. L. Jacques, L. Wang. “Montecarlo modeling of light transport tissues”. Optical-Thermal Response of LaserIrradiated Tissue. J. Ashley Welsh, Martin J. C. van Gemert (editors). Ed. Plenum Press. New York (USA). 2005. pp. 73-99. DOI: https://doi.org/10.1007/978-1-4757-6092-7_4
B. W. Pogue, M. S. Patterson. “Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry”. Journal of Biomedical Optics. Vol. 11. 2006. pp. 1-16. DOI: https://doi.org/10.1117/1.2335429
H. J. van Staveren, C. J. M. Moes, J. van Marle, S. A. Prahl, M. van Gemert. “Light scattering in intralipid-10% in the wavelength range of 400-1100 nm.” App. Opt. Vol. 30. 1991. pp. 4507-4514. DOI: https://doi.org/10.1364/AO.30.004507
C. J. M Moes, M. J. C. van Gemert, W.M. Star, P. A. Marijnissen, S. A. Prahl. “Measurements and calculations of the energy fluence rate in a scattering and absorbing phantom at 633 nm”. App. Opt. Vol. 28. 1989. pp. 2292-2296. DOI: https://doi.org/10.1364/AO.28.002292
S. A. Prahl. Light Transport in tissue, Dissertation for the Degree of Doctor of Philosophy. University of Texas. USA. 1988. pp. 63-99.
S. L. Jacques, S. A. Prahl. Steady-state Monte Carlo: A minimal program. ECE532 Biomedical Optics. Oregon Graduate Institute. 1998. en: http://omlc.ogi.edu/classroom/ece532/class4/ssmc/mc321.c. Consultado el 18 mayo 2011.
Photochem CAD Spectra by Category. en: http://omlc.ogi.edu/spectra/PhotochemCAD/abs_html/OEP.html. Consultado el 18 mayo 2011.
Tuan Vo-Dihn. Biomedical Photonics Handbook. Ed. CRC Press LCL. USA. 2003. pp. 80-101. DOI: https://doi.org/10.1201/9780203008997
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2018 Revista Facultad de Ingeniería
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Revista Facultad de Ingeniería, Universidad de Antioquia is licensed under the Creative Commons Attribution BY-NC-SA 4.0 license. https://creativecommons.org/licenses/by-nc-sa/4.0/deed.en
You are free to:
Share — copy and redistribute the material in any medium or format
Adapt — remix, transform, and build upon the material
Under the following terms:
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
The material published in the journal can be distributed, copied and exhibited by third parties if the respective credits are given to the journal. No commercial benefit can be obtained and derivative works must be under the same license terms as the original work.
Twitter