Management of patients on anticoagulant therapy undergoing dental extractions: a systematic review


  • Patricio Oliva-Mella Universidad del Desarrollo
  • Maria Francisca Ruiz-Gutiérrez Universidad del Desarrollo



Anticoagulants, Extraction, Hemorrhages


Introduction: the management of patients who have undergone dental surgeries and are on antithrombotic therapy is debatable. The goal of this study was to establish the management of patients on anticoagulant therapy prior to dental extractions. Methods: this was a systematic review based on the search for scientific randomized controlled studies (clinical trials). Articles were searched in databases such as Embase, Pubmed, or Ebsco, selecting the articles that met the inclusion criteria and correlated dental extractions to the use of anticoagulant therapy. Results: 5 studies were found with a total of 548 patients, 282 of which had their anticoagulant therapy modified and the remaining 266 kept their therapy prior to extractions. The number of events (hemorrhages) was measured in both groups, observing that most events occurred in the group of patients whose therapy was modified (35 events) while there were 18 cases in patients who kept their therapy. Heterogeneity in this study was null (I² = 0%, p = 0.99). Conclusion: there are no significant differences in the hemorrhage levels of patients who maintain anticoagulant therapy compared with those who had their therapy modified prior to dental extractions. It is then recommended to keep the treatment.

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Author Biographies

Patricio Oliva-Mella, Universidad del Desarrollo

PhD in Biomedical Research, M.Sc. in Clinical Epidemiology. Research Coordinator, School of Dentistry, Universidad del Desarrollo. Concepción, Chile

Maria Francisca Ruiz-Gutiérrez, Universidad del Desarrollo

DMD, Guest Researcher, Research Department, School of Dentistry, Universidad del Desarrollo. Concepción, Chile.


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How to Cite

Oliva-Mella, P., & Ruiz-Gutiérrez, M. F. (2016). Management of patients on anticoagulant therapy undergoing dental extractions: a systematic review. Revista Facultad De Odontología Universidad De Antioquia, 27(2), 389–403.

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