Serum concentration of thyroxine and triiodothyronine in newborn calves from cows supplemented with barium selenate

  • Víctor R. Leyán Austral University of Chile
  • Ricardo H. Chihuailaf Austral University of Chile
  • Fernando G. Wittwer Austral University of Chile
Keywords: barium selenate, bovine, calves, cows, glutathione peroxidase, mineral nutrition, selenium, supplementation, thyroid hormones, thyroxine, triiodothyronine

Abstract

Background: Barium selenate is an inorganic source of selenium (Se) used in prolonged-release preparations to treat selenium deficiency in bovines. Objective: To evaluate serum concentrations of triiodothyronine (T3) and thyroxine (T4) hormones in newborn calves from mothers supplemented with barium selenate during prepartum. Methods: Six black Frisian pregnant cows were supplemented with barium selenate subcutaneously during the last two months of gestation, until calving. Six cows were used as controls. All cows were subjected to a low Se diet, consisting of hay from natural pasture and commercial concentrate lacking Se. The Se balance was measured through the activity of erythrocyte glutathione peroxidase (GPx). Serum concentration of T3 and T4 in calves was determined by electrochemiluminescence. Results: Se supplementation during prepartum increased GPx activity in cows from day 45 post-supplementation (p<0.05). Calves from supplemented mothers showed higher average serum Se concentration than calves from non-supplemented mothers. The average concentration of T3 in the calves from supplemented mothers was lower in the first hour of life (p<0.05) compared with calves from mothers of the non-supplemented group. A decrease (p<0.05) in T4 serum concentrations was observed in both groups at seven days of age. Conclusions: Administration of barium selenate to cows during prepartum generates a reduction in serum concentration of T3 in the first hour of life of calves.

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Author Biographies

Víctor R. Leyán, Austral University of Chile

https://orcid.org/0000-0003-3308-9884
Institute of Immunology, Faculty of Medicine, Austral University of Chile, Valdivia, Chile.

Ricardo H. Chihuailaf, Austral University of Chile

https://orcid.org/0000-0002-9463-8552
Institute of Veterinary Clinical Sciences, Faculty of Veterinary Sciences, Austral University of Chile, Valdivia, Chile.

Fernando G. Wittwer, Austral University of Chile

https://orcid.org/0000-0003-4631-4796
Institute of Veterinary Clinical Sciences, Faculty of Veterinary Sciences, Austral University of Chile, Valdivia, Chile.

References

Awadeh FT, Kincaid RL, Johnson KA. Effecto flevel and source of dietary selenium on concentrations of thyroid and immunoglobulins in beef cows and calves. J Anim Sci 1998; 76(4):1204-1215. DOI: https://doi.org/10.2527/1998.7641204x

Beckett GJ, Arthur JR. Selenium and endocrine systems. JEndocrinol2005; 184(3):455-465. DOI: https://doi.org/10.1677/ioe.L05971

Carstens G. Cold thermoregulation in the newborn calf. Vet Clin North Am Food Anim Pract 1994; 10:69-106. DOI: https://doi.org/10.1677/ioe.L05971

Carvalho DP, Dupuy C. Thyroid hormone biosynthesis and release. Mol Cel Endocrinol 2017; 458(1):6-15. DOI: https://doi.org/10.1016/i. mce.2017.01.038

Ceballos A, Wittwer F. Metabolismo del selenio en rumiantes. Arch Med Vet 1996; 28(2):5-18. Available at: https://www. researchgate.net/profile/Fernando_ Wittwer/publication/28743 642 1_ Selenium_metabolism_in_ruminants/ links/569d48d808aed27a702f9e6c/Selenium-metabolism-in-ruminants.pdf

Contreras PA, Matamoros R, Monroy R, Kruze J, Leyán V, Andaur M, Bóhmwald H, Wittwer F. Effect of a Selenium deficient diet on blood values of T3 and T4 in cows. Comp Clin Path 2002; 11(2): 65-70. DOI: https://doi.org/10.1007/s005800200000

Contreras PA, Wittwer F, Matamoros R, Mayorga IM, van Schaik G. Effect of grazing pasture with a low selenium content on the concentrations of triiodothyronine and thyroxine in serum, and GSH-Px activity in erythrocytes in cows in Chile. N Z Vet J 2005(1); 53:77-80. DOI: https://doi.org/10.1080/00480169.2005.36472

Davicco MJ, Vigouroux E, Dardillat C, Barlett JP. Thyroxine, triiodothyronine and iodide in different breeds of newborn calves. Reprod Nutr Dévelop 1982; 22(2):352-362. DOI: https://doi. org/10.1051/rnd:19820306

Davis PA, McDowell LR, vanAlstyne R, Marshall TT, Buergelt CD, Weldon RN, Wilkinson NS. Effects of form of parenteral or dietary selenium supplementation on body weight and blood, liver, and milk concentrations in beef cows. Prof Anim Sci 2008(1); 24:52-59. DOI: https://doi.org/10.15232/S1080-7446(15)30810-X

Grongnet JF, Grongnet-Pinchon E, Witowski A. Neonatal levels of plasma thyroxine in male and female calves fed a colostrum or immunoglobulin diet or fasted for the first 28 hours of life. Reprod Nutr Dévelop 1985; 25(3):537-543. DOI: https://doi.org/10.1051/rnd:19850406

Gunter SA, Beck PA, Hallford DM. Effects of supplementary selenium source on the blood parameters in beef cow and their nursing calves. Biol Trace Elem Res 2013; 152(2):204-211. DOI: https://doi.org/10.1007/s12011-013-9620-0

Guyot H, de Oliveira LA, Ramery E, Beckers JF, Rollin F. Effect of a combined iodine and selenium supplementation on I and Se status of cows and their calves. J Trace Elem Med Biol 2011; 25(2):118-124. DOI: https://doi.org/10.1016/i.jtemb.2011.02.003

Judson GJ, Babidge PJ. Depot iniection of barium selenate for long-term prevention of selenium in adequacy in beef cattle. Aust Vet J 2010; 88(4):154-155. DOI: https://doi.org/10.1111/i.1751-0813.2010.00555.x

Juniper DT, Phipps RH, Ramos-Morales E, Bertin G. Effect of dietary supplementation with selenium-enriched yeast or sodium selenite on selenium tissue distribution and meat quality in beef cattle. J Anim Sci 2008(11); 86:3100-3109. DOI: https://doi.org/10.2527/ias.2007-0595

Kirovski D, Lazarevic M, Baricevic-Jones I, Nedic O, Masnikosa R, Nikolic JA. Effects of peroral insulin and glucose on circulating insulin-like growth factor-I, its binding proteins and thyroid hormones in neonatal calves. Can J Vet Res 2008; 72(3):253-258. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC2327243/pdf/civr72 pg253.pdf

Koenig KM, Beauchemin KA. Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves. Can J Anim Sci 2009; 89(1):111-122. DOI: https://doi.org/10.4141

Leyán V, Wittwer F, Contreras PA, Kruze J. Concentraciones de inmunoglobulinas séricas y calostrales de vacas selenio deficientes y en el suero sanguíneo de sus terneros. Arch Med Vet 2004; 36(2):155-162. DOI: http://dx.doi. org/10.4067/S0301-732X2004000200006

Leyán V, Wittwer F, Contreras PA, Schurig G. Efecto de una dieta con baio aporte de selenio sobre la respuesta inmune a la vacuna Brucella abortus Cepa RB51 en vacas lecheras. Arch Med Vet 2006; 38(2):129-135. DOI: http://dx.doi. org/10.4067/S0301-732X2006000200006

Muñiz-Naveiro O, Domínguez-González R, Bermeio-Barrera A, Cocho JA, Fraga JM, Bermeio-Barrera P. Determination of total selenium and selenium distribution in the milk phases in commercial cow's milk by HG-AAS. Anal Bioanal Chem 2005; 381(6):1145-1151. DOI: https://doi.org/10.1021/if050155w

NRC-National Research Council. Nutrient Requirements ofDairy Cattle. 7th ed. Washington DC: Natl. Acad. Press; 2001. p.141-43. DOI: https://doi.org/10.17226/9825

Ortman K, Pehrson B. Effect of selenate as a feed supplement to dairy cows in comparison to selenite and selenium yeast. J Anim Sci 1999; 77(12):3365-3370. DOI: https://doi.org/10.2527/1999.77123365x

Rose M, Pearson S, Cratchley T. Effect of iodine, selenium and cobalt rumen boluses given to dry dairy cows on the immunoglobulin and thyroid hormone status of calves. Anim Sci J 2012; 83(7):543-548. DOI: https://doi.org/10.1111/ i.1740-0929.2011.00991.x

Rowntree JE, Hill GM, Hawkins DR, Link JE, Rincker MJ, Bednar GW, Kreft Jr RA. Effect of Se on selenoprotein activity and thyroid hormone metabolism in beef and dairy cows and calves. J Anim Sci 2004; 82(10):2995-3005. DOI: https://doi.org/10.2527/2004.82102995x

Slavik P, Illek J, Brix M, Hlavicova J, Raimon R, Jilek F. Influence of organic versus inorganic dietary selenium supplementation on the concentration of selenium in colostrum, milk and blood of beef cows. Acta Vet Scand 2008; 50:43-48. DOI: https://doi.org/10.1186/1751-0147-50-43

Stadtman TC. Selenium biochemistry. Mammalian selenoenzymes. Ann N Y Acad Sci 2000; 899(1):399-402. DOI: https://doi. org/10.1111/i.1749-6632.2000.tb06203.x

Stanko RL, Guthrie MJ, Randel RD. Response to environmental temperatures in Brahman calves during the first compared to the second day after birth. J Anim Sci 1991; 69(11):4419-4427. DOI: https://doi.org/10.2527/1991.69114419x

Stojic V, Nikolic JA, Huszenicza GY, Samanc H, Vozdic G, Kirovski D. Plasma levels of triiodothyronine, thyroxine and cortisol in newborn calves. Acta Vet-Beograd 2002; 52:85-96. DOI: https://doi.org/10.2298/AVB0203085S

Suttle N. The mineral nutrition of livestock. 4th ed. Oxfordshire (UK): MPG Books Group; 2010. p.306-33. DOI: http://dx.doi.org/10.1079/9781845934729.0000

Takahashi K, Takahashi E, Ducusin RJ, Tanabe S, Uzuka Y, Sarashina T. Changes in serum thyroid hormone levels in newborn calves as a diagnostic index of endemic goiter. J Vet Med Sci 2001; 63(2):175-178. DOI: https://doi. org/10.1292/ivms.63.175

Voudouri AE, Chadio SE, Menegatos JG, Zervas GP, Nicol F, Arthur JR. Selenoenzyme Activities in Selenium-and Iodine-Deficient Sheep. Biol Trace Elem Res 2003; 94(3):213-224. DOI: https://doi.org/10.1385/BTER:94:3:213

Published
2020-09-07
How to Cite
Leyán V. R., Chihuailaf R. H., & Wittwer F. G. (2020). Serum concentration of thyroxine and triiodothyronine in newborn calves from cows supplemented with barium selenate. Revista Colombiana De Ciencias Pecuarias, 34(2), 145-153. https://doi.org/10.17533/udea.rccp.v34n2a03
Section
Short communications