Laryngeal amyloidosis, a clinical challenge: A case series in the Hospital Universitario San Ignacio, Bogotá- Colombia
DOI:
https://doi.org/10.17533/udea.iatreia.64Keywords:
amyloidosis, dysphonia, larynxAbstract
Laryngeal amyloidosis in an infrequent disorder, with nonspecific symptoms that difficult the diagnosis and without a consensus for its treatment. Through the description, analysis and comparison of three cases of laryngeal amyloidosis at the Hospital Universitario San Ignacio Bogotá, we seek to expand the knowledge in this pathology and compare it with what is described in the literature. We made a retrospective research of patients with a diagnosis of laryngeal amyloidosis in the last five years in our institution, obtaining a final sample of 3 cases that met the inclusion criteria. The most frequent symptom was dysphonia, the most frequent presentation was systemic, contrary to what was reported in the literature. Airway remodeling was performed using laryngeal microsurgery with carbon dioxide laser, obtaining good clinical results. We consider important to carry out more studies on the subject in our country.
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(1) Rudy SF, Jeffery CC, Damrose EJ. Clinical characteristics of laryngeal versus nonlaryngeal amyloidosis. Laryngoscope [Internet]. 2018 Mar [cited 2019 Feb 22];128(3):670-4. Availablef from: https://doi.org/10.1002/lary.26846
(2) Behnoud F, Baghbanian N. Isolated laryngeal amyloidosis. Iran J Otorhinolaryngol [Internet]. 2013 [cited 2019 Feb 22];25(70):49-52. Available from: https://doi.org/10.22038/ijorl.2013.672
(3) Passerotti GH, Caniello M, Hachiya A, Santoro PP, Imamura R, Tsuji DH. Multiple-sited amyloidosis in the upper aerodigestive tract: case report and literature review. Braz J Otorhinolaryngol [Internet]. 2008 May 1 [cited 2019 Apr 21];74(3):462-6. Available from: https://doi.org/10.1016/S1808-8694(15)30584-X
(4) Caporrino Neto J, Alves NSC, Gondra L de A. Laryngeal amyloidosis presenting as false vocal fold bulging: clinical and therapeutic aspects. Braz J Otorhinolaryngol [Internet]. 2015 Mar [cited 2019 Feb 22];81(2):219-21. Available from: https://doi.org/10.1016/j.bjorl.2015.01.001
(5) Wechalekar AD, Gillmore JD, Hawkins PN. Systemic amyloidosis. Lancet [Internet]. 2016 Jun 25 [cited 2019 Feb 26];387(10038):2641-54. Available from: https://doi.org/10.1016/S0140-6736(15)01274-X
(6) Flint P, Haughey B, Lund V, Niparko J, Robbins K, Regan Thomas RT. Cummings Otolaryngology ClinicalKey. 6nd ed. EE. UU: Elsevier; 2014.
(7) Stavrakas M, Psillas G, Rachovitsas D, Triaridis S. Laryngeal Amyloidosis: An Interesting Presentation of Voice Quality Deterioration. Ear Nose Throat J. 2020 Feb;99(2):128–9. DOI 10.1177/0145561319837473.
(8) Phillips NM, Matthews E, Altmann C, Agnew J, Burns H. Laryngeal amyloidosis: diagnosis, pathophysiology and management. J Laryngol Otol [Internet]. 2017 Jul 30 [cited 2019 Feb 22];131(S2):s41-7. Available from: https://doi.org/10.1017/S0022215117000780
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