Mycophenolate-induced eosinophilic colitis: A case report
DOI:
https://doi.org/10.17533/udea.iatreia.211Keywords:
Colitis, Mycophenolic Acid, DiarrheaAbstract
Mycophenolate mofetil is a medication used for the prevention of allograft rejection in organ transplant patients. Eosinophilic colitis due to mycophenolate is a recognized condition in patients with a history of renal transplantation and persistent diarrhea, requiring a biopsy to achieve an appropriate diagnosis and treatment. The case of an 11-year-old boy with diarrhea is presented; colon biopsy showed edema and eosinophilic inflammatory infiltrate in the lamina propria with microabscess formation, with epithelial and crypt damage. Because of the absence of another cause of the clinical case, mycophenolate was withdrawn from the treatment scheme, with resolution of the symptoms. The Naranjo adverse drug reaction probability scale was definitive with a score of 10. It contributes to the literature with the characterization of the histopathological findings in mycophenolate-induced colonic injury.
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