Molecular bases of septic shock
DOI:
https://doi.org/10.17533/udea.iatreia.3508Keywords:
Septic shock, Multisystemic organic failureAbstract
An analysis of recently described molecules acting as mediators in the pathogenesis of septic shock is made. The different actions these endogenous mediators generate in response to infectious processes are explained as well as the mechanisms through which their functional, biochemical and metabolic properties produce the panendothelial lesion. The latter appears to be central to the multisystemic organic failure.
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