Characterization of Pulmonary Function in Colombian COVID-19 Survivors
DOI:
https://doi.org/10.17533/udea.iatreia.265Keywords:
COVID-19, Spirometry, Oxygen ConsumptionAbstract
Introduction: SARS-CoV-2 acutely affects human pulmonary function, and respiratory alterations may persist after overcoming the infection.
Objectives: To characterize the pulmonary function among Colombian survivors of COVID-19.
Methods: A pilot study was conducted where pulmonary function was assessed using a MiniBox™ device, aerobic fitness with a six-minute walk test, and fatigue perception with the Multidimensional Fatigue Inventory (MFI-20).
Results: Out of an initial group of 70 participants, only 39 completed the study, with a disease course ranging from mild to moderate. Women comprised the majority (51%) of the participants, and no abnormal values were found in pulmonary function. The total fatigue score was 39 ± 9.2; for general fatigue, it was 5 ± 0, the same as for physical fatigue (5 ± 0); for mental fatigue, the score was 8.56 ± 3.5; for reduced activity, it was 11.2 ± 2.96, and for reduced motivation, it was 9.38 ± 4.4. Additionally, the peak oxygen co sumption (VO2 peak) was 19.51 ml/kg/min ± 2.8 ml/kg/min.
Conclusions: Pulmonary function and fatigue levels in Colombian COVID-19 survivors residing in Bogotá who did not require ventilatory support were normal according to the tests performed, while cardiopulmonary fitness was low.
Downloads
References
Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents [Internet]. 2020;55(3):105924. https://doi.org/10.1016/j.ijantimicag.2020.105924
Buss PM, Tobar S. COVID-19 and opportunities for international cooperation in health. Cad Saude Publica [Internet]. 2020;36(4). https://doi.org/10.1590/0102-311x00066920
Sierra-Sierra S, Arbeláez-Salgado MA, Cadavid-Congote A, Flórez-Filomeno DR, Garcés-Otero JS, Machado-Gómez A, et al. COVID-19: Temas de interés para el cirujano. Rev Colomb Cir [Internet]. 2020;35(2):153-61. https://doi.org/10.30944/20117582.612
Trujillo-Saavedra CH. ADENDO: ACTUALIZACIÓN 27/06/2020. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-CoV-2/COVID-19 en establecimientos de atención de la salud: Recomendaciones basadas en consenso de expertos e informadas en la evidencia ACIN-IETS. SEGUNDA EDICIÓN. Infectio [Internet]. 2020;24(3). https://doi.org/10.22354/in.v24i3.895
Tang X, Du RH, Wang R, Cao TZ, Guan LL, Yang CQ, et al. Comparison of hospitalized patients with ARDS caused by COVID-19 and H1N1. Chest [Internet]. 2020;158(1):195-205. https://doi.org/10.1016/j.chest.2020.03.032
Zhang H, Zhou P, Wei Y, Yue H, Wang Y, Hu M, et al. Histopathologic changes and SARS-CoV-2 immunostaining in the lung of a patient with COVID-19. Ann Intern Med [Internet]. 2020;172(9):629-32. https://doi.org/10.7326/M20-0533
Orme JrJ, Romney JS, Hopkins RO, Pope D, Chan KJ, Thomsen G, et al. Pulmonary function and health-related quality of life in survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med [Internet]. 2003;167(5):690-4. https://doi.org/10.1164/rccm.200206-542OC
Van-den-Borst B, Peters JB, Brink M, Schoon Y, Bleeker-Rovers CP, Schers H, et al. Comprehensive health assessment 3 months after recovery from acute coronavirus disease 2019 (COVID-19). Clin Infect Dis [Internet]. 2021;73(5):e1089-98. https://doi.org/10.1093/cid/ciaa1750
Ranzieri S, Corradi M. Conducting spirometry in occupational health at COVID-19 times: international standards. Med Lav [Internet]. 2021;112(2):95. Available from: https://www.mattioli1885journals.com/index.php/lamedicinadellavoro/article/view/11420
Sastre SLS. Capacidad de difusión de monóxido de carbono: principios teóricos, formas de medición y aplicaciones clínicas. Neumosur Rev Asoc Neumólogos Sur [Internet]. 1990;2(2):57-75. Available from: https://www.rev-esp-patol-torac.com/files/publicaciones/Revistas/1990/NS1990.02.2.A07.pdf
Calderón-Elizondo J. Síndrome de fatiga. Med Leg Costa Rica [Internet]. 2017;34(2):76-81. Available from: https://www.scielo.sa.cr/scielo.php?pid=S1409-00152017000200076&script=sci_abstract&tlng=es
Sukocheva OA, Maksoud R, Beeraka NM, Madhunapantula SV, Sinelnikov M, Nikolenko VN, et al. Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue syndrome. J Adv Res [Internet]. 2022;40:179-96. https://doi.org/10.1016/j.jare.2021.11.013
Berger KI, Adam O, Dal Negro RW, Kaminsky DA, Shiner RJ, Burgos F, et al. Validation of a novel compact system for the measurement of lung volumes. Chest [Internet]. 2021;159(6):2356-2365. https://doi.org/10.1016/j.chest.2021.01.052
Schumacher AN, Shackelford DY, Brown JM, Hayward R. Validation of the 6-min walk test for predicting peak VO2 in cancer survivors. Med Sci Sports Exerc [Internet]. 2019;51(2):271-7. https://doi.org/10.1249/MSS.0000000000001790
David AS, Wessely SC. The legend of Camelford: medical consequences of a water pollution accident. J Psychosom Res [Internet]. 1995;39(1):1-9. https://doi.org/10.1016/0022-3999(94)00085-J
Viechtbauer W, Smits L, Kotz D, Budé L, Spigt M, Serroyen J, et al. A simple formula for the calculation of sample size in pilot studies. J Clin Epidemiol [Internet]. 2015;68(11):1375-9. https://doi.org/10.1016/j.jclinepi.2015.04.014
Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, et al. Standardization of spirometry 2019 update. An official American thoracic society and European respiratory society technical statement. Am J Respir Crit Care Med [Internet]. 2019;200(8):e70-88. https://doi.org/10.1164/rccm.201908-1590ST
You J, Zhang L, Zhang J, Hu F, Chen L, Dong Y, et al. Anormal pulmonary function and residual CT abnormalities in rehabilitating COVID-19 patients after discharge. J Infect [Internet]. 2020;81(2):e150-2. https://doi.org/10.1016/j.jinf.2020.06.003
Berhane K, McConnell R, Gilliland F, Islam T, Gauderman WJ, Avol E, et al. Sex-specific effects of asthma on pulmonary function in children. Am J Respir Crit Care Med [Internet]. 2000;162(5):1723-30. https://doi.org/10.1164/ajrccm.162.5.2001116
Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-monthconsequencesof COVID-19inpatientsdischargedfromhospital: acohortstudy. Lancet [Internet]. 2021;397(10270):220-32. https://doi.org/10.1016/S0140-6736(20)32656-8
Mo X, Jian W, Su Z, Chen M, Peng H, Peng P, et al. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J [Internet]. 2020;55(6):2001217. https://doi.org/10.1183/13993003.01217-2020
Lewis KL, Helgeson SA, Tatari MM, Mallea JM, Baig HZ, Patel NM. COVID-19 and the effects on pulmonary function following infection: a retrospective analysis. EClinicalMedicine [Internet]. 2021;39:101079. https://doi.org/10.1016/j.eclinm.2021.101079
Eksombatchai D, Wongsinin T, Phongnarudech T, Thammavaranucupt K, Amornputtisathaporn N, Sungkanuparph S. Pulmonary function and six-minute-walk test in patients after recovery from COVID-19: A prospective cohort study. PloS One [Internet]. 2021;16(9):e0257040. https://doi.org/10.1371/journal.pone.0257040
Walteros-Manrique RE. Distancia recorrida de la prueba de caminata de seis minutos en población adulta sana en una comunidad universitaria de la ciudad de Bogotá [Tesis]. Bogotá: Universidad Nacional de Colombia; 2018. Available from: https://repositorio.unal.edu.co/bitstream/handle/unal/64204/RaulWalteros.2018.pdf?sequence=1&isAllowed=y
Lugo-Pérez LM, Angulo-Lobelo JP, Prieto LV, del Gordo-Quijano CIQ, Henríquez ES. Distancia recorrida en la prueba de caminata de seis minutos en población adulta sana en una institución de salud de la ciudad de Barranquilla. Rev Colomb Neumol [Internet]. 2020;32(2):20-6. https://doi.org/10.30789/rcneumologia.v32.n2.2020.529
Guler SA, Ebner L, Aubry-Beigelman C, Bridevaux PO, Brutsche M, Clarenbach C, et al. Pulmonary function and radiological features 4 months after COVID-19: first results from the national prospective observational Swiss COVID-19 lung study. Eur Respir J [Internet]. 2021;57(4). https://doi.org/10.1183/13993003.03690-2020
Haddad-Herdy A, Uhlendorf D. Valores de Referencia para el Test Cardiopulmonar para Hombres y Mujeres Sedentarios y Activos. Arq Bras Cardiol [Internet]. 2011;96(1):54-59. https://doi.org/10.1590/S0066-782X2010005000155
Vásquez-Gómez J, Castillo-Retamal M, Carvalho RS de, Faundez-Casanova C, Portes Junior MDP. Six-Minute Walk Test. Is It Possible to Predict Oxygen Consumption in People with Pathologies? A Bibliographic Review. MHSalud [Internet]. 2019;16(1):1-17. https://doi.org/10.15359/mhs.16-1.1
Vainshelboim B, Oliveira J, Yehoshua L, Weiss I, Fox BD, Fruchter O, et al. Exercise training-based pulmonary rehabilitation program is clinically beneficial for idiopathic pulmonary fibrosis. Respiration [Internet]. 2014;88(5):378-88. https://doi.org/10.1159/000367899
Villarroel-Bustamante K, Jérez-Mayorga DA, Campos-Jara C, Delgado-Floody P, Guzmán-Guzmán IP. Función pulmonar, capacidad funcional y calidad de vida en pacientes con fibrosis pulmonar idiopática. Revisión de la literatura. Rev Fac Med [Internet]. 2018;66(3):411-7. https://doi.org/10.15446/revfacmed.v66n3.63970
Cortés-Telles A, López-Romero S, Figueroa-Hurtado E, Pou-Aguilar YN, Wong AW, Milne KM, et al. Pulmonary function and functional capacity in COVID-19 survivors with persistent dyspnoea. Respir Physiol Neurobiol [Internet]. 2021;288:103644. https://doi.org/10.1016/j.resp.2021.103644
Szekely Y, Lichter Y, Sadon S, Lupu L, Taieb P, Banai A, et al. Cardiorespiratory abnormalities in patients recovering from coronavirus disease 2019. J Am Soc Echocardiogr [Internet]. 2021;34(12):1273-84. https://doi.org/10.1016/j.echo.2021.08.022
Aparisi Á, Ybarra-Falcón C, García-Gómez M, Tobar J, Iglesias-Echeverría C, Jaurrieta-Largo S, et al. Exercise ventilatory inefficiency in post-COVID-19 syndrome: insights from a prospective evaluation. J Clin Med [Internet]. 2021;10(12):2591. https://doi.org/10.3390/jcm10122591
Shah AS, Wong AW, Hague CJ, Murphy DT, Johnston JC, Ryerson CJ, et al. A prospective study of 12-week respiratory outcomes in COVID-19-related hospitalisations. Thorax [Internet]. 2021;76(4):402-4. https://doi.org/10.1136/thoraxjnl-2020-216308
Lin JMS, Brimmer DJ, Maloney EM, Nyarko E, BeLue R, Reeves WC. Further validation of the Multidimensional Fatigue Inventory in a US adult population sample. Popul Health Metr [Internet]. 2009;7(1):1-13. https://doi.org/10.1186/1478-7954-7-18
Morin L, Savale L, Pham T, Colle R, Figueiredo S, Harrois A, et al. Four-month clinical status of a cohort of patients after hospitalization for COVID-19. Jama [Internet]. 2021;325(15):1525-34. https://doi.org/10.1001/jama.2021.3331
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Iatreia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Papers published in the journal are available for use under the Creative Commons license, specifically Attribution-NonCommercial-ShareAlike 4.0 International.
The papers must be unpublished and sent exclusively to the Journal Iatreia; the author uploading the contribution is required to submit two fully completed formats: article submission and authorship responsibility.
