Processing, characterization and biological testing of electrochemically modified titanium for dental implants
DOI:
https://doi.org/10.17533/udea.redin.18305Keywords:
dental implant, biomaterial, surfaces, osteointegration, chemical and electrochemical modifications, titaniumAbstract
Biomedical applications of titanium and its alloys are possible due to their suitable characteristics for bone replacement, including good mechanical properties, excellent corrosion resistance and high biocompatibility. However, one of their main limitations is the fibrous tissue capsule that is formed around the material, which can be related with implants loosening. As an alternative to solve this problem, in this work were carried out some chemical and electrochemical modifications of titanium surface, in order to evaluate their influence on implants osteointegration through in vitro testing in contact with osteoblasts. Results of scanning electron microscopy (SEM), roughness parameters measured and osteoblasts morphology indicate that there is a relationship between surface roughness and bone cells adhesion. Surfaces with highest vertical roughness parameters, within evaluated conditions, allowed better cells adhesion. These results suggest that a combination of chemical and electrochemical techniques can help to control surface roughness of titanium dental implants and, by this way, it can also allow to optimize osteointegration.
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References
J. Park. Biomaterials: principles and applications. Bronzino J, Park J. D. (Editor). 1st ed. Ed.CRC Press. Boca Raton, Fl, Estados Unidos. 2003. pp. 1-20.
L. Hench. “Bioceramics: from concept to clinic”. J Am Ceram Soc. Vol. 74. 1991. pp. 1487-1510. DOI: https://doi.org/10.1111/j.1151-2916.1991.tb07132.x
S. Cook, K. Thomas, R. Hadd, M. Harcho, J. Kay. “Hydroxylapatite-coated titanium for orthopaedic implant applications”. Clin Orthop Relat R. Vol. 232. 1988. pp. 225-231. DOI: https://doi.org/10.1097/00003086-198807000-00030
H. Kim, F. Miyaji, T. Kokubo, T. Nakamura. “Preparation of bioactive Ti and its alloys via simple chemical surface treatment”. J Biomed Mater Res. Vol. 32. 1996. pp. 409-417. DOI: https://doi.org/10.1002/(SICI)1097-4636(199611)32:3<409::AID-JBM14>3.0.CO;2-B
C. Aparicio, F. Gil, J. Planell, E. Engel. “Humanosteoblast proliferation and differentiation on gritblasted and bioactive titanium for dental applications”. J Mater Sci Mater Med. Vol. 13. 2003. pp. 1105-1111. DOI: https://doi.org/10.1023/A:1021173500990
J. Park, J. Davies. “Red blood cell and platelet interactions with titanium implant surfaces”. Clin Oral Implants Res. Vol. 11. 2000. pp. 530-539. DOI: https://doi.org/10.1034/j.1600-0501.2000.011006530.x
L. Guéhennec, A. Soueidan, P. Layrolle, Y. Amouriq. "Surface treatments of titanium dental implants for rapid osseointegration: Review". Dental materials. Vol. 23. 2007. pp. 844-854. DOI: https://doi.org/10.1016/j.dental.2006.06.025
L. Xie, G. Yin, D. Yan, X. Liao, Z. Huang, Y. Yao, Y. Kang, Y. Liu. “Structure, morphology and fibroblasts adhesion of surface-porous titanium via anodic oxidation”. J Mater Sci: Mater Med. Vol. 21. 2010. pp. 259-266. DOI: https://doi.org/10.1007/s10856-009-3832-z
K. Das, S. Bose, A. Bandyopadhyay. “Surface modifications and cell–materials interactions with anodized Ti”. Acta Biomaterialia. Vol. 3. 2007. pp. 573-585. DOI: https://doi.org/10.1016/j.actbio.2006.12.003
J. Pavón, P. Velásquez, S. Velásquez. Modificación superficial del titanio para mejorar su oseointegración. VI Encuentro Nacional de Materiales Módulo Metales. Universidad de Antioquia. Medellín, Colombia. Octubre, 2010.
M. Wield. Experimental Determination and quantitative evaluation of the surface composition and topography of medical implant surfaces and their influence on osteoblastic cell-surface interactions. PhD Thesis. Swiss Federal Institute of Technology (ETH). Zürich, Switzerland. 1999. pp. 132-158.
F. Denizot, R. Lang. “Rapid colorimetric assay for cell growth and survival: Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability”. J Immunol Methods. Vol. 89. 1986. pp. 271-277. DOI: https://doi.org/10.1016/0022-1759(86)90368-6
M. Echeverry. Evaluación de la oseointegración mediante ensayos biológicos de Ti c.p y Ti6Al4V Anodizados. Tesis de Maestría. Universidad de Antioquia. Medellín, Colombia. 2012. pp. 32-60.
A. Karambakhsh, A. Afshar, S. Ghahramani, P. Malekinejad. “Pure commercial Titanium color anodizing and corrosion resistance”. J Mater Eng Perform. Vol. 20. 2011. pp.1690-1696. DOI: https://doi.org/10.1007/s11665-011-9860-0
A. Pérez, P. Serra, J. Morenza. “Coloring of titanium by pulsed laser processing in air”. Thin Solid Films. Vol. 415. 2002. pp. 201-205. DOI: https://doi.org/10.1016/S0040-6090(02)00632-6
B. Boyan, Z. Schwartz. “Modulation of osteogenesis via implant surface design”. Davies J., Vacanti J. P. Bone Engineering. 1st ed. Ed. Squared Inc. Toronto, Canada. 1999. pp. 72-89.
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