Oral pathogen candida in patients under antineoplastic therapies

  • Martha Rebolledo-Cobos Universidad Metropolitana de Barranquilla. Colombia
  • Marisol Sánchez-Molina Universidad Metropolitana de Barranquilla
Keywords: neoplasia, cancer, candidiasis, Candida antineoplastic treatment, Candida, antineoplastic treatment, infection

Abstract

Cancer control treatments are aimed at prolonging patient survival, but they also trigger inevitable and irreversible side effects, often infectious in nature, complicating the prognosis of the oncological disease. These include the pathogenic behavior of Candida, with Albicans being its most common species in the oral mucosa. Albicans is considered a commensal fungus that, as a result of the neutropenia resulting from antineoplastic therapies, behaves as an opportunistic entity causing candidiasis. This fungal infection has aggravating factors for the patient, such as xerostomia and hyposalivation, infections like dental caries, and other factors such as improper oral hygiene. Several consulted authors highlight the presence of Candida, its different species and oral candidiasis as a microorganism and classic opportunistic infection in immunosuppressed patients, and even more in those subjected to antineoplastic treatments. The aim of this review is to describe the pathogenic behavior of Candida in the oral mucosa of patients under antineoplastic treatments.

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Author Biographies

Martha Rebolledo-Cobos, Universidad Metropolitana de Barranquilla. Colombia
DDS. Stomatologist and Oral Surgeon. MSc in Molecular Genetics. Assistant research professor in Pathology, Semiology, and Oral Surgery, Universidad Metropolitana de Barranquilla.
Marisol Sánchez-Molina, Universidad Metropolitana de Barranquilla
DDS. MSc in Microbiology, Universidad Metropolitana de Barranquilla. Assistant professor in Formative Research, Universidad Metropolitana de Barranquilla

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Published
2018-12-20
How to Cite
Rebolledo-Cobos M., & Sánchez-Molina M. (2018). Oral pathogen candida in patients under antineoplastic therapies. Revista Facultad De Odontología Universidad De Antioquia, 30(1), 92-104. https://doi.org/10.17533/udea.rfo.v30n1a9