Eye-related neoplasms in dogs: a retrospective study
DOI:
https://doi.org/10.17533/udea.rccp.v32n4a07Keywords:
adenoma, canine, dog, eyelid, eye globe, eye-related neoplasms, Meibomian gland, ocular neoplasia, tumorAbstract
Background: Eye-related neoplasms in dogs have a significant impact on visual ability, comfort, and longevity. Therapeutic alternatives and prognosis vary according to type of neoplasm and its anatomical location. Objective: To describe the frequency and distribution of eye-related neoplasms affecting dogs in Aburrá valley (Antioquia province, Colombia). Methods: A retrospective collection of eye-related neoplasms in dogs, diagnosed at the Animal Pathology Laboratory of Universidad de Antioquia (Colombia), was conducted. Data spanning from years 2005 to 2017 were used. Records included age, sex, breed, neoplasm type and location, and cellular origin of neoplasm. A total of 250 eye-related-neoplasm reports affecting 246 dogs were analyzed -one report per animal, with the exception of four animals with both eyes simultaneously affected by the same type of neoplasm. Results: Animals between 8 and 11 years of age were more frequently affected by eye-related neoplasms (43.9%). Labrador retriever (19.1%), mixed-breed dogs (13.4%), and Poodle (12.2%) were the most frequently affected breeds. Neoplasms affected the eyelid in 76.8% of cases. Meibomian gland adenoma was the most frequent neoplasm (22.8%), followed by Meibomian gland epithelioma (20.0%), squamous cell carcinoma (8.8%), and melanocytoma (7.2%). The cellular origin of neoplasms [i]was epithelial in 73.6% of the cases. Conclusion: Meibomian gland adenoma was the most common eye-related neoplasm. To our knowledge, this is the first retrospective report aimed to eye-related neoplasms in dogs published in Colombia.
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Abarca E, Font A, Closa JM, Mascort J. Tumores orbitarios en el perro. Estudio retrospectivo de 9 casos clínicos. AVEPA 2002; 22(3):247-255.
Busse C, Sansom J, Dubielzig RR, Hayes A. Corneal squamous cell carcinoma in a Border Collie. Vet Ophthalmol 2008; 11(1):55-58.https://doi.org/10.1111/j.1463-5224.2007.00594.x
Campos CB, Nunces FC, Gamba CO, Damasceno KA, Souza CM, Campos LC, Cassali GD. Canine low-grade intra-orbital myxosarcoma: Case report. Vet Ophthalmol 2015; 18(3):251-253. https://doi.org/10.1111/vop.12183.
Conceição LF, Pinto A, Trujillo DY, Laus JL. Considerations about ocular neoplasia of dogs and cats. Ciencia Rural 2010; 40(10):2235-2242. https://doi.org/10.1053/j.ctsap.2007
Dees DD, Schobert CS, Dubielzig RR, Stein TJ. Third eyelid gland neoplasms of dogs and cats: a retrospective histopathologic study of 145 cases. Vet Ophthalmol 2015; 19(2):1-6. https://doi.org/10.1111/vop.12273
Dreyfus J, Schobert CS, Dubielzig RR. Superficial corneal squamous cell carcinoma occurring in dogs with chronic keratitis. Vet Ophthalmol 2011; 14(3):161-168. https://doi.org/10.1111/j.1463-5224.2010.00858.x.
Dubielzig RR, Ketring KL, McLellan GJ, Albert DM. Veterinary ocular pathology: A comparative review. Saunders Ltd, Edinburgh, 2010.
Dubielzig RR. Tumors of the eye. In: Tumors in domestic animals. 5th edition (ed. Meuten DJ). John Wiley & Sons, Inc: Wisconsin, 2017; 892-922.
Fernandez BR. Neoplasias oculares em cães e gatos: Estudo retrospectivo 2001-2012. Lisboa: Universidade técnica de Lisboa; 2013.
Gelatt PKN. Veterinary ophthalmology: Our past, present and future. Bull Acad Vet Fr. 2008; 161(4):299-306.
Goldschmidt MH, Goldschmidt KH. Epithelial and melanocytic tumors of the skin. In: Tumors in Domestic Animals. 5th edition (ed. Meuten DJ). John Wiley & Sons, Inc: Wisconsin, 2017; 88-104.
Heath S, Rankin AJ, Dubielzig R. Primary ocular osteosarcoma in a dog. Vet Ophthalmol 2003; 6(1):85-87.
Hendrix DV, Gelatt KN. Diagnosis, treatment and outcome of orbital neoplasia in dogs: A retrospective study of 44 cases. J Small Anim Pract 2000; 41(3):105-108.
Hirai T, Mubarak M, Kimura T, Ochiai K, Itakura C. Apocrine gland tumor of the eyelid in a dog. Vet Pathol. 1997 May; 34(3):232-4.
Labelle L, Labelle P. Canine ocular neoplasia: A review. Vet Ophthalmol 2013; 16 (1):3-14. https://doi.org/10.1111/vop.12062
Laus JL, Ortiz JPD, Brito FLC, Lisbão CBS, Silva Júnior VA, Maia FCL. Hemangiosarcoma of the nictitant membrane in a Brazilian Fila dog: Case report. Arq Bras Med Vet Zootec 2008; 60(6):1413-1417. https://doi.org/10.1590/S0102-09352008000600016
Lew M, Lew S, Rozicka A. Upper eyelid and medial canthus reconstructive surgery after histiocytoma resection in a dog: A case report. Vet Medicína (Praha) 2010; 55(3):137-143.
Milo J, Snead E. A case of ocular canine transmissible venereal tumor. CVMA 2017; 55:1245-1249.
Nordio L, Fattori S, Giudice C. Fibrosarcoma of the eyelid in two sibling Czech wolfdogs. Open Vet J 2017; 7(2):95-99. https://doi.org/10.4314/ovj.v7i2.3
Okawauchi M, Tsuboi M, Nibe K, Nagamine E, Iwane H, Uchida K. Iridociliary adenocarcinoma with oncocytic change in a dog. JVMS 2016; 78(5):883-887. https://doi.org/10.1292/jvms.15-0721
Petterino C, Bjornson S, Hayes S. What is your diagnosis? An intraocular mass in a dog. Vet Clin Pathol 2014; 43(2):289-290. https://doi.org/10.1111/vcp.12129
Silva B, Peleteiro M, Pissarra H. Tumors of the eye and ocular adnexa in cats and dogs. In: Ocular diseases (ed. Group S). SM Group: Dover, 2016; 1-11.
Simko E, Wilcock BP, Yager JA. A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. CVMA 2003; 44:38-42.
Stern AW, Eisele LP. Apocrine adenocarcinoma in the eyelid of a miniature Pinscher. BJVP 2011; 4(2):142-144.
Takiyama N, Terasaki E, Uechi M. Corneal squamous cell carcinoma in two dogs. Vet Ophthalmol 2010; 13 (4):266-269. https://doi.org/10.1111/j.1463-5224.2010.00792.x
Tavasoli A, Javanbakht J, Shafiee R, Kamyabi-moghaddam Z, Aghamohammad Hassan M. Cytological and histopathology features of Meibomian adenocarcinoma in a dog Terrier breed. J Clin Experiment Pathol 2012; 2(5):120.https://doi.org/10.4172/2161-0681.1000120
Teixeira TF, Silva TC, Cogliati B, Nagamine MZ, Dagli MLZ. Retrospective study of melanocytic neoplasms in dogs and cats. BJVP 2010; 3(2):100-104.
Wang AL, Kern T. Melanocytic ophthalmic neoplasms of the domestic veterinary species: A review top companion. Anim Med 2015; 30(4):148-157. https://doi.org/10.1053/j.tcam.2015.06.001
Werner J, Moura CMC, Werner PR, Montiani-Ferreira F. Canine tarsal gland epitheliomas and adenomas: a retrospective study of 290 cases in Brazil. BJVP 2017; 10(1):2-9. https://doi.org/10.24070/bjvp.1983-0246.v10i1p2-9
Wilcock B, Dubielzig R, Render J. Histological classification of ocular and otic tumors of domestic animals. In: World Health Organization International Histologic Classification of Tumors in Domestic Animals. Armed Forces Institute of Pathology, American Registry of Pathology: Washington DC, 2002.
Withrow SJ, Vail DM, Page R. Small animal clinical oncology. 5th ed. Philadelphia: Saunders Company; 2013. 768 p.
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