Parámetros de estrés oxidativo en perros naturalmente infectados con sarna sarcóptica
DOI:
https://doi.org/10.17533/udea.rccp.v36n4a2Palabras clave:
biomarcador, estrés oxidativo, infestación, perro, Sarcoptes, sarna sarcóptica, escabiosis, zoonosisResumen
Antecedentes: La sarna es una de las enfermedades más comunes en perros. Es una amenaza para la salud animal y humana por su carácter zoonótico. Objetivo: El propósito de esta investigación fue estudiar el balance oxidante/antioxidante con hallazgos hematológicos en perros infestados por sarna sarcóptica. Métodos: Los perros del grupo Sarcoptes presentaban signos de infestación tales como prurito intenso, excoriaciones, alopecia y ampollas en el codo y márgenes auriculares. El estudio evaluó 32 perros mestizos entre 1 y 2 años de edad. Los perros se distribuyeron en dos grupos: un grupo control (animales libres de infestación; n=10), y un grupo con sarna sarcóptica (Sarcoptes; n=22). Resultados: Se encontró un aumento significativo (p<0.01) en el estado oxidante total (TOS), malondialdehído (MDA), índice de estrés oxidativo (OSI) y niveles de óxido nítrico (NO), mientras que el glutatión (GSH) y los niveles de estado antioxidante total (TAS) de los perros infestados por Sarcoptes disminuyeron significativamente (p<0.01). Además, se encontró un aumento significativo (p<0,01) en el recuento de leucocitos de los perros del grupo Sarcoptes en comparación con el control. Por el contrario, hubo disminuciones significativas (p<0,01) en los recuentos de RBC, HGB y PCV de los perros infestados. Conclusiones: Podría sugerirse una posible relación entre el desequilibrio oxidante/antioxidante y los hallazgos hematológicos en perros infestados por sarna sarcóptica. Adicionalmente, los marcadores MDA, TAS, TOS y OSI, el NO y el GSH podrían utilizarse para evaluar el estrés oxidativo en perros infectados naturalmente por Sarcoptes scabiei.
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- 2024-09-24 (2)
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