Compuestos de hierro para suplementación oral: principios y avances - revisión sistemática -
DOI:
https://doi.org/10.17533/udea.vitae.528Abstract
Se lleva a cabo una revisión que abarca los principales aspectos sobre la absorción del hierro (fuentes y captación) y sus funciones en el organismo, centrada en la tendencia actual de utilizar complejos o quelatos de este metal con ligandos orgánicos para el tratamiento oral por deficiencia (monosacáridos, aminoácidos y ácidos carboxílicos de bajo peso molecular), ya que estos compuestos aumentan la biodisponibilidad del hierro y disminuyen los efectos adversos que presentan sus sales inorgánicas a nivel gastrointestinal. Se describen los hallazgos más relevantes en la síntesis y caracterización de estos compuestos para uso farmacéutico, como suplemento nutricional. Por último se explican algunas de las principales interacciones del hierro con otros componentes de la dieta.Downloads
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