Clinical, epidemiological and virological findings of the first COVID-19 outbreak in Medellín, Antioquia, Colombia

Authors

  • Carlos Hernando Velásquez Cuadros Gobernación de Antioquia
  • Rita Elena Almanza Payares Alcaldía de Medellín https://orcid.org/0000-0003-1781-6025
  • Yury Johana Silva López Instituto Nacional de Salud

DOI:

https://doi.org/10.17533/udea.rfnsp.e344675

Keywords:

Wuhan coronavirus outbreak, COVID-19, Medellín (Colombia), public health surveillance

Abstract

Objective: To characterize clinically, epidemiologically and virologically the first outbreak of covid-19, from the primary case in Medellín (Colombia), through surveillance and epidemiological control carried out for its containment.

Methodology: Retrospective descriptive study. Secondary cases are identified taking into account the definition of the protocol of the National Institute of Health. Data collection was obtained of the Public Health Surveillance System, research epidemiological field, medical history and results of laboratory. Clinical patterns of the disease (signs and symptoms), epidemiological components (transmission surveillance and control actions) and virological (with the use of the diagnostic test for sars-CoV-2 and the evaluation of virological recovery). The confirmation of the cases was done by the diagnostic detection technique of Wuhan coronavirus 2019 by reverse transcription polymerase Chain Reaction - Real Time, Charité protocol, Berlin, Germany 2020, processed in and reported by the National Laboratory of Reference of the National Institute of Health.

Results: The Medellín's primary case entered the country on March 2, 2020, from Madrid (Spain) and was confirmed on March 9. 52 close contacts were identified in 9 clusters. The surveillance actions in public health made it possible to identify 5 related cases in an early phase of the disease.

Conclusions: The characterization of the primary case in Medellín seek to identify the first outbreak of covid-19 and guide the epidemiological control measures, such as isolations, intakes of samples, follow-up contacts and case searches secondary

|Abstract
= 1433 veces | PDF (ESPAÑOL (ESPAÑA))
= 422 veces| | HTML (ESPAÑOL (ESPAÑA))
= 13 veces|

Downloads

Download data is not yet available.

References

World Health Organization. Novel Coronavirus (2019-nCoV). Situation Report - 1 21 January 2020 [internet]; 2020 [citado 2020 may. 21]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200121-sitrep-1-2019-ncov.pdf

World Health Organization. Novel Coronavirus ( 2019-nCoV ). Situation Report - 10 [internet]. 2020. [citado 2020 may. 21] . Disponible en: https://apps.who.int/iris/handle/10665/330775

World Health Organization. Novel Coronavirus ( 2019-nCoV ). Situation Report - 11 [internet]. 2020. [citado 2020 may. 21]. Disponible en: https://apps.who.int/iris/handle/10665/330776

Pan American Health Organization, World Health Organization. Actualización epidemiológica: enfermedad por coronavirus - (covid-19) 20 de abril de 2020 [internet]; 2020 [citado 2020 may. 21]. Disponible en: https://www.paho.org/es/documentos/actualizacion-epidemiologica-enfermedad-por-coronavirus-covid-19-20-abril-2020

World Health Organization. Coronavirus disease 2019 (covid-19): Situation Report 51 - 11th March 2020 [internet]; 2020 [citado 2020 may. 21]. Disponible en: https://apps.who.int/iris/handle/10665/331475

Organización Panamericana de la Salud (ops), Organización Mundial de la Salud (oms). Respuesta de la ops/oms. 31 de marzo del 2020. Informe N.o 1 [internet]; 2020 [citado 2020 may. 21]. Disponible en: https://iris.paho.org/bitstream/handle/10665.2/52404/COVID-19SitRep1_spa.pdf?sequence=1&isAllowed=y

Instituto Nacional de Salud. Protocolo de vigilancia en salud pública. Infección Respiratoria Aguda (ira) códigos: 345, 348, 591, 995 [internet]; 2020. [citado 2020 may. 21]. Disponible en: https://www.ins.gov.co/buscador-eventos/Lineamientos/Pro_Infección respiratoria aguda.pdf

Instituto Nacional de Salud. (covid-19), Anexo. Instructivo para la vigilancia en salud pública intensificada de infección respiratoria aguda asociada al nuevo coronavirus 2019.

Instituto Nacional de Salud . Dirección de Vigilancia y Análisis del Riesgo en Salud Pública, Grupo de Formación de Talento Humano para la Vigilancia en Salud Pública. Lineamientos para la elaboración de productos gfth. Lineamientos para la elaboración de productos gfth - Atención de brotes o emergencias en salud pública [internet]; 2016. [citado 2020 may. 21]. Disponible en: https://www.ins.gov.co/Direcciones/Vigilancia/Lineamientosydocumentos/Manual de ateción a brotes.pdf

Ortiz-Prado E, Simbaña-Rivera K, Gómez-Barreno L, et al. Clinical, molecular, and epidemiological characterization of the sars-CoV-2 virus and the Coronavirus Disease 2019 (covid-19), acomprehensive literature review. Diagn Microbiol Infect Dis. 2020; 98(1). doi: https://doi.org/10.1016/j.diagmicrobio.2020.115094

Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-Infected pneumonia in Wuhan, China. jama. 2020;323(11):1061-9. doi: https://doi.org/10.1001/jama.2020.1585

Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020;395(10223):507-13. doi: http://dx.doi.org/10.1016/S0140-6736(20)30211-7

Sultan S, Altayar O, Siddique SM, et al. aga Institute rapid review of the gastrointestinal and liver manifestations of covid-19, meta-analysis of international data, and recommendations for the consultative management of patients with covid-19. Gastroenterology. 2020;159(1):320-334.e27. doi: http://dx.doi.org/10.1053/j.gastro.2020.05.001

Zahra SA, Iddawela S, Pillai K, et al. Can symptoms of anosmia and dysgeusia be diagnostic for covid-19? Brain Behav. 2020;10(1):1-18. https://doi.org/10.1002/brb3.1839

Carrillo-Larco RM, Altez-Fernandez C. Anosmia and dysgeusia in covid-19: A systematic review [versión 1; peer review: 2 approved, 1 not approved]. Wellcome Open Res 2020;5:94. doi: https://doi.org/10.12688/wellcomeopenres.15917.1

Meng X, Deng Y, et al. covid-19 and anosmia: A review based on up-to-date knowledge. Am J Otolaryngol. 2020;41(5):102581. doi: https://doi.org/10.1016/j.amjoto.2020.102581

Bi Q, Wu Y, Mei S, et al. Epidemiology and transmission of covid-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: A retrospective cohort study. Lancet Infect Dis. 2020;20(8):911-9. doi: https://doi.org/10.1016/S1473-3099(20)30287-5

Chan JFW, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. Lancet. 2020;395(10223):514-23. doi: http://dx.doi.org/10.1016/S0140-6736(20)30154-9

Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. Euro Surveillance. 2020;25(5):20-28. doi: https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000062

Organización Mundial de Salud. Preguntas y respuestas sobre la enfermedad por coronavirus (covid-19) [internet]. s. f. [citado 2020 may. 21]. Disponible en: https://www.who.int/es/emergencies/diseases/novel-coronavirus-2019/advice-for-public/q-a-coronaviruses

Centers for Disease Control and Prevention. Symptoms of covid-19 [internet]. s. f. [citado 2020 may. 21]. Disponible en: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html

Sheng W-H, Liu W-D, Wang J-T, et al. Dysosmia and dysgeusia in patients with covid-19 in northern Taiwan. J Formos Med Assoc. 2020;120(1 Parte 2):311-7. doi: https://doi.org/10.1016/j.jfma.2020.10.003

Published

2021-09-30

How to Cite

1.
Velásquez Cuadros CH, Almanza Payares RE, Silva López YJ. Clinical, epidemiological and virological findings of the first COVID-19 outbreak in Medellín, Antioquia, Colombia. Rev. Fac. Nac. Salud Pública [Internet]. 2021 Sep. 30 [cited 2026 Mar. 3];40(1):e344675. Available from: https://revistas.udea.edu.co/index.php/fnsp/article/view/e344675

Issue

Section

Condiciones de salud

Categories