Extubation in neurocritical patients with acute brain injuries, narrative review of the literature

Authors

  • Bryan Álvarez-Arango IPS Universitaria Clínica León XIII, Medellín, Colombia. https://orcid.org/0000-0001-9019-6622
  • Andrea González-Medina Instituto Neurológico de Colombia. Medellín Colombia. https://orcid.org/0000-0002-8178-1616
  • Sebastián Valencia-Valencia IPS Universitaria Clínica León XIII, Medellín, Colombia. https://orcid.org/0000-0003-0680-2488
  • Yessica Andrea Tamayo-Aristizábal Instituto Neurológico de Colombia, Medellín, Colombia.
  • Danny Steven Pantoja-Rojas IPS Universitaria Clínica León XIII, Medellín, Colombia. https://orcid.org/0000-0002-8646-840X
  • Karen Alejandra Vélez-Puerta Universidad de Antioquia, Medellín, Colombia.

DOI:

https://doi.org/10.17533/udea.iatreia.180

Keywords:

Airway Extubation, Brain Injuries, Traumatic, Critical Care, Neurologic Manifestations, Weaning

Abstract

Introduction: Ventilator weaning and extubation in patients with acute brain injuries pose a challenge for healthcare professionals due to the lack of clear consensus on extubation criteria.
Objective: To summarize the available evidence on extubation of patients with acute brain injuries and analyze potential alternatives to the classical
extubation criteria.
Methods: A literature search was conducted in the Spanish and English languages, covering the last 20 years, across different databases. Systematic
reviews with or without meta-analysis, guidelines and recommendations from scientific societies, clinical trials, and observational studies that met
the inclusion criteria were included.
Results: A total of 262 relevant articles were collected, of which, through analysis and comparison of the evidence, 48 articles were selected as most relevant to fulfill the stated objective.
Conclusions: The available evidence is weak in providing a recommendation on extubation criteria for neurocritical patients. Early extubation could be considered in patients with a minimal level of consciousness while maintaining protective airway reflexes, without an increase in reintubation rate or mortality.

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Author Biographies

Bryan Álvarez-Arango, IPS Universitaria Clínica León XIII, Medellín, Colombia.

Médico intensivista en la unidad de cuidados intensivos de la IPS Universitaria Clínica León XIII, Medellín, Colombia.

Andrea González-Medina, Instituto Neurológico de Colombia. Medellín Colombia.

Médica General. Instituto Neurológico de Colombia. Medellín Colombia.

Sebastián Valencia-Valencia, IPS Universitaria Clínica León XIII, Medellín, Colombia.

Médico General. Unidad de cuidado intensivo IPS Universitaria Clínica León XIII, Medellín, Colombia.

Yessica Andrea Tamayo-Aristizábal, Instituto Neurológico de Colombia, Medellín, Colombia.

Terapeuta respiratorio. Instituto Neurológico de Colombia, Medellín, Colombia.

Danny Steven Pantoja-Rojas, IPS Universitaria Clínica León XIII, Medellín, Colombia.

Médico general. Unidad de cuidado intensivo IPS Universitaria Clínica León XIII, Medellín, Colombia.

Karen Alejandra Vélez-Puerta, Universidad de Antioquia, Medellín, Colombia.

Médica general. Bienestar Universitario, Universidad de Antioquia, Medellín, Colombia.

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Published

2022-08-16

How to Cite

1.
Álvarez-Arango B, González-Medina A, Valencia-Valencia S, Tamayo-Aristizábal YA, Pantoja-Rojas DS, Vélez-Puerta KA. Extubation in neurocritical patients with acute brain injuries, narrative review of the literature. Iatreia [Internet]. 2022 Aug. 16 [cited 2025 Feb. 5];36(3). Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/350922

Issue

Section

Review articles