Péptidos antimicrobianos como nueva alternativa para las infecciones de la cavidad oral. Una revisión de la literatura

Claudia Andrea Cruz-Baquero; José David Rueda-Gutierrez; Laura Pérez-Abshana

doi:10.17533/udea.iatreia.353

Authors

Claudia Andrea Cruz-Baquero Universidad Colegio Mayor de Cundinamarca, Bogotá D.C., Colombia https://orcid.org/0000-0003-1041-9609
José David Rueda-Gutierrez Universidad Colegio Mayor de Cundinamarca, Bogotá D.C., Colombia
Laura Pérez-Abshana Hospital General de Medellín Luz Castro de Gutiérrez, Medellín, Colombia https://orcid.org/0000-0002-2047-7194

DOI:

https://doi.org/10.17533/udea.iatreia.353

Keywords:

Antimicrobial Peptides, Gingivitis, Periodontitis, Viral Drug Resistance

Abstract

Introduction: Microorganisms involved in oral cavity infections are a subject of the utmost importance, given that their eradication is complicated due to the increase of strains resistant to antibiotics commonly used to control these infections. However, the use of antibiotics is not uniform in all countries and, therefore, the resistance profile of microbial species is also diverse.

Objective: To identify alternatives in scientific literature for the treatment of oral cavity infections, highlighting on the novel use of synthetic antimicrobial peptides.

Methods: This review analyzed some general aspects of oral cavity infections, their causal microorganisms and the available treatments, highlighting synthetic antimicrobial peptides as a therapeutic alternative for oral cavity infections.

Results: Several alternatives for the treatment of oral cavity infections produced by anaerobic bacteria were evidenced, highlighting the studies performed with LL-37 c y 19-4LF peptides, among others.

Conclusions: Synthetic antimicrobial peptides are emerging as a complementary proposal for the treatment of oral cavity infections.

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Author Biographies

Claudia Andrea Cruz-Baquero, Universidad Colegio Mayor de Cundinamarca, Bogotá D.C., Colombia

Researcher, REMA group, Universidad Colegio Mayor de Cundinamarca, Bogota D.C., Colombia.

José David Rueda-Gutierrez, Universidad Colegio Mayor de Cundinamarca, Bogotá D.C., Colombia

Student of the REMA research group, Universidad Colegio Mayor de Cundinamarca, Bogota D.C., Colombia.

Laura Pérez-Abshana, Hospital General de Medellín Luz Castro de Gutiérrez, Medellín, Colombia

Bacteriologist, Hospital General de Medellin Luz Castro de Gutierrez, Medellin, Colombia.

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