Péptidos antimicrobianos como nueva alternativa para las infecciones de la cavidad oral. Una revisión de la literatura
DOI:
https://doi.org/10.17533/udea.iatreia.353Palabras clave:
Farmacorresistencia Viral, Gingivitis, Péptidos Antimicrobianos, PeriodontitisResumen
Introducción: los microorganismos causales de infecciones de la cavidad oral constituyen un tema de suma importancia, dado que su erradicación es cada vez más complicada debido al aumento de cepas resistentes a los antibióticos que comúnmente se usan para controlar esas infecciones. No obstante, el uso de antibióticos no es uniforme en todos los países y, por lo tanto, el perfil de resistencia de las especies microbianas también es diverso.
Objetivo: identificar en la literatura científica las alternativas para el tratamiento de las infecciones de la cavidad oral, con énfasis en el uso de novedosos péptidos antimicrobianos sintéticos.
Métodos: se analizan aspectos generales de las infecciones de la cavidad oral, los microorganismos causales y las estrategias de tratamiento disponibles, resaltando los péptidos antimicrobianos sintéticos como una opción terapéutica emergente para esas infecciones.
Resultados: se evidenciaron varias alternativas novedosas para el tratamiento de las infecciones de la cavidad oral producidas por bacteria anaerobias, destacándose los estudios realizados con diversos péptidos como LL-37 c y 19-4LF, entre otros.
Conclusiones: los péptidos antimicrobianos sintéticos se han posicionado como una propuesta complementaria para el tratamiento de las infecciones de la cavidad oral.
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