Pregnancy and glomerulonephritis. A review
DOI:
https://doi.org/10.17533/udea.iatreia.4476Keywords:
Dialysis, Glomerulonephritis, Pregnancy, Renal biopsy, Renal failure, Segmental focal sclerosisAbstract
Antecedent: Glomerulal involvement is rare during pregnancy, but the associated morbidity is serious and potentially lethal. How does it affect prognosis?
Objective: To define guidelines for the care of women affected by glomerulal disease during the pregestational stage, gestation and puerperium, and the indications for dialysis and renal biopsy.
Materials and methods: Analysis of textual revisions published between 1980 and 1992, and the publications of Medline between 1993 and 2007 (Pregnancy and Glomerulonephritis).
Results: Few randomized controlled studies were found. Most studies were cross-sectional and cases series, but they allow the assertion that glomerulonephritis adversely affects gestational outcomes and that pregnancyfavors renal damage and the lupus flare.
Conclusion: The incidence of exacerbation of glomerulonephritis is higher during pregnancy and the perinatal and maternal outcomes are affected, especially in the presence of preeclampsia or antiphospholipid syndrome.
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