Comparison of the effects of three mouth rinses in the management of oral mucositis secondary to the treatment of acute lymphoblastic leukemia in children

  • Diana María Barbosa-Liz Universidad de Antioquia
  • Lucía Victoria Bernal-de Jaramillo Universidad de Antioquia
  • Carolina Gallego-González Universidad de Antioquia
  • Margarita E. Sierra-Sánchez HUSVP
Keywords: Oral mucositis, Leukemia, Chemotherapy, Oral rinses

Abstract

Introduction: the present study was conducted to compare the effects of three mouth rinses in the treatment of oral mucositis induced by chemotherapy in children between 3 and 15 years of age, with acute lymphoblastic leukemia and who were hospitalized at the Pediatric hemato oncology Pavilion of the san Vicente de Paul university hospital in the city of Medellin. Methods: three mouth rinses were compared: triconjugate diphenhydramine, milk of magnesia (magnesium hydroxide) and lidocaine in gel; sucralfate comprising sucralfate suspended and lidocaine in gel; and a third rinse, called control consisting of lidocaine in gel; nistatin was added to the mouth rinses to avoid fungal infection. each group had 3 daily rinses with the assigned mouth rinse and a daily log was made with information related to the severity of mucositis and duration of the episode. the type of study was a quasi-experimental comparative blind design, the sample had 14 cases (triconjugate with 6 cases, 4 in the sucralfate group and 4 in the control group) and collection of the sample was made over a period of 32 months between april 2005 and november 2007. Results and conclusion: no statistically significant differences were found in the severity nor on the length of mucositis among the rinses used by the patients.

|Abstract
= 397 veces | PDF (ESPAÑOL (ESPAÑA))
= 57 veces|

Downloads

Download data is not yet available.

Author Biographies

Diana María Barbosa-Liz, Universidad de Antioquia

Odontóloga, especialista en Estomatología pediátrica de la Universidad nacional de Bogotá, especialista en Odontología Integral del Adolescente y Ortodoncia, Universidad de antioquia. Estudiante de Maestría en Educación y Desarrollo Humano en el CINDE, Universidad de Manizales. Docente asistente de Posgrado en la Facultad de Odontología de la Universidad de Antioquia.

Lucía Victoria Bernal-de Jaramillo, Universidad de Antioquia

Odontóloga, especialista en Odontología Integral del Niño, Universidad de Antioquia, Docente asistente de Pregrado y Posgrado de la Facultadd e Odontología de la Universidad de Antioquia.

Carolina Gallego-González, Universidad de Antioquia

Odontóloga, Universidad de Antioquia

Margarita E. Sierra-Sánchez, HUSVP

Médica General Universidad Pontificia Bolivariana. Médica Pediatra Universidad de Antioquia. Oncóloga de la Universidad París VII Instituto Gustave Roussy, Hospital Saint Louis de París. Coordinadora del Servicio de Hematooncología Infantil del HUSVP.

Published
2009-08-19
How to Cite
Barbosa-Liz D. M., Bernal-de Jaramillo L. V., Gallego-González C., & Sierra-Sánchez M. E. (2009). Comparison of the effects of three mouth rinses in the management of oral mucositis secondary to the treatment of acute lymphoblastic leukemia in children. Revista Facultad De Odontología Universidad De Antioquia, 20(2), 179-190. Retrieved from https://revistas.udea.edu.co/index.php/odont/article/view/2141