Dental caries prevalence in children and youths with vertically-transmitted HIV/AIDS from the pediatric HIV clinic (Cali, Colombia) and its relationship with biological factors, 2013

Authors

  • María Cristina Arango-de la Cruz Universidad del Valle
  • Carlos Alberto Velasco-Benítez Universidad del Valle
  • Pío López-López Universidad del Valle

DOI:

https://doi.org/10.17533/udea.rfo.v29n2a2

Keywords:

Dental caries, HIV/AIDS, Epidemiology

Abstract

Introduction: among the oral pathologies afflicting children with HIV/AIDS is dental caries, a preventable disease if detected and controlled in its early stages to avoid further complications. The aim of this study was to determine the prevalence of caries in children and youths with vertically-transmitted HIV/AIDS from the Pediatric HIV Clinic in Cali, Colombia, in 2013, and to explore relationships with biological factors. Methods: descriptive prevalence study in 101 clinical records of children and youths aged 1 to 17 years with vertically-transmitted HIV/AIDS from the Pediatric HIV Clinic in Cali. The ICDAS and DMF/def classification systems were used. Multivariate analysis and confounding variable adjustment were included to explore relationships with demographic, paraclinical, nutritional, and dental factors. The institutional ethics committees endorsed the study. Results: the prevalence of caries experience in children with HIV was 34.65% DMF/deft (5-6) 3.29 ± 3.06. This prevalence increases 83.17% with the ICDAS 2-6 system. The point prevalence of active caries was 74.26% DMFT 5.68 ± 5.48. No statistically significant association was found with any socioeconomic or immunologic variables. Patients with moderate to severe immunosuppression had OR 1.13 CI95% (0.33-3.81) p = 0.84. A probable association was found with plaque index OR 4.58 CI95% (1.44-14.55) p = 0.006 and caries experience OR 4.21 CI95% (1,09-16.13) Conclusion: HIV patients from the Pediatric Clinic show high caries prevalence when pre-cavitated lesions are assessed. No probable association was found between caries and immunological or clinical status, and therefore this aspect is not an additional risk factor.

|Abstract
= 745 veces | PDF
= 283 veces|

Downloads

Download data is not yet available.

Author Biographies

María Cristina Arango-de la Cruz, Universidad del Valle

DDM. Esp. in Pediatric Dentistry and Maxillary Orthopedics. Professor at Universidad del Valle, School of Dentistry

Carlos Alberto Velasco-Benítez, Universidad del Valle

Pediatrician. Gastroenterologist and nutritionist. Professor. Universidad del Valle. Cali, Colombia.

Pío López-López, Universidad del Valle

Pediatrician. Infectious Disease Specialist. Professor. Universidad del Valle. Cali, Colombia

References

WHO. UNAIDS. UNICEF. Global HIV/AIDS response: epidemic update and health sector progress towards universal access: progress report 2011. Geneva: World Health Organization, 2011.

Beltrán S, López P, Sierra A. Recomendaciones para el abordaje, diagnóstico y tratamiento de niños, niñas y adolescentes con VIH/SIDA. 2 ed. Cali : Catorse SCS; 2011

Colombia. Ministerio de Salud y Protección Social. Informe UNGASS – 2012: seguimiento de la declaración de compromiso sobre el VIH/Sida: informe mundial de avances en la lucha contra el Sida, Colombia 2012. Bogotá: Ministerio de Salud y Protección Social; 2012.

Niños con VIH en Cali tienen más opciones de vida [Internet]. El Pais. 2012 jul 02. Available in: http://www.elpais.com.co/cali/ninos-con-vih-en-tienen-mas-opciones-de-vida.html

Fejerskov O, Kidd E. Dental caries: the disease and its clinical management. 2 ed. Copenhagen, Denmark: Blackwell Munksgaard; 2008

Klein H, Palmer CE; Knutson JW. Studies on dental caries. I. Dental status and dental needs of elementary school. J Am Dent Assoc. 1938; 25(10): 1703-1705. DOI: https://doi.org/10.14219/jada.archive.1938.0274

Pitts NB, Deery C, Fyffe HE, Nugent ZJ. Caries prevalence surveys. A multi-country comparison of caries diagnostic criteria. Com Den Health. 2000; 17: 196-203.

Banting D, Eggertsson H, Ekstrand K, Ferreira A , Ismail A, Longbotto et al. Manual sobre los Criterios del Sistema Internacional de Detección y Valoración de Caries(ICDAS II), Taller realizado en Baltimore, Maryland el 12 al 14 de marzo del 2005.

Ekstrand KR, Martignon S, Ricketts DJN, Qvist V. The validity of a classification system for clinical activity assessment of primary coronal caries lesions. Caries Res. 2005; 39(4): 299-300. Abstract No. 38

Ismail AI, Sohn W, Tellez M, Amaya A, Sen A, Hasson H et al. The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol. 2007; 35(3): 170-178. DOI: https://doi.org/10.1111/j.1600-0528.2007.00347.x

Braga MM, Oliveira LB, Bonini GA, Bönecker M, Mendes FM. Feasibility of the International Caries Detection and Assessment System (ICDAS-II) in epidemiological surveys and comparability with standard World Health Organization criteria. Caries Res. 2009; 43(4): 245-249. DOI: https://doi.org/10.1159/000217855

Hernández-Ramírez JR, Gómez-Clavel JF. Determinación de la especificidad y sensibilidad del ICDAS y fluorescencia láser en la detección de caries in vitro. Rev ADM. 2012; 69(3): 120-124.

Colombia. Ministerio de Salud y Protección Social. IV estudio nacional de salud bucal (ENSAB IV). Bogotá: Ministerio de Salud y Protección Social; 2014

Eldridge K, Gallagher J. Dental caries prevalence and dental health behaviour in HIV infected children. Int J Paediatr Dent. 2000; 10(1): 19-26.

Pongsiriwet S, Lamaroon A, Kanjanavanit S, Pattanaporn K, Krisanaprakornkit S. Oral lesions and dental caries status in perinatally HIV-infected children in Northern Thailand. Int J Ped Dentistry. 2003; 13(3): 180–185.

Pinzón EM, Bravo SM, Méndez F, Clavijo GM, León ME. Prevalencia y factores relacionados con la presencia de manifestaciones orales en pacientes con VIH/SIDA, Cali Colombia. Colomb Méd. 2008; 39(4): 346-55

Marín M, Hurtado P, Santamaría L, Durango A, Patiño C, Toro M. Estado de salud bucal de niños con diagnóstico de VIH-sida en la fundación Eudes de Medellín. Presentación de casos y revisión de literatura. Rev Fac Odontol Univ Antioq. 2004; 15(2): 64-77

Ponnam SR, Srivastava G, Theruru K. Oral manifestations of human immunodeficiency virus in children: An institutional study at highly active antiretroviral therapy centre in India. J Oral Maxillofac Pathol. 2012; 16(2): 195-202. https://doi.org/10.4103/0973-029X.98499

Mosca N. With HAART success, managing dental caries is again important. HIV Clin. 2002; 14(1): 6-7

Ribeiro AdA , Portela MB, De-Souza IP. The oral health of HIV-infected Brazilian children. Int J Paediatr Dent. 2013; 23(5): 359–365. DOI: https://doi.org/10.1111/ipd.12008

Sahana S, Krishnappa SS, Krishnappa VS. Low prevalence of dental caries in children with perinatal HIV infection. J Oral Maxillofac Pathol. 2013; 17(2): 212-216. DOI: https://doi.org/10.4103/0973-029X.119742

Rwenyonyi CM, Kutesa A, Muwazi L, Okullo I, Kasangaki A, Kekitinwa A. Oral manifestations in HIV/AIDS infected children. Eur J Dentistry. 2011; 5: 291-298.

Sales-Peres SHdC, Mapengo MAA, Moura-Grec PGd, Marsicano JA, Sales-Peres AdC, Sales-Peres A. Oral manifestations in HIV+ children in Mozambique. Ciênc Saúde Coletiva. 2012; 17(1): 55-60 DOI: http://dx.doi.org/10.1590/S1413-81232012000100008

Trejos-Herrera AM, Mosquera-Vásquez M, Tuesca-Molina R. Niñez afectada con VIH/SIDA: calidad de vida, funcionalidad familiar y apoyo social en cinco ciudades colombianas. Salud UNINORTE. 2009; 25(1): 17-32

Buczynski AK, Castro GF, Souza IPR. O impacto da saúde bucal na qualidade de vida de crianças infectadas pelo HIV: revisão de literatura. Ciênc Saúde Coletiva. 2008; 13(6) : 1797-1805. DOI: 10.1590/S1413-81232008000600014

Cavasin Filho JC, Giovani EM. Xerostomy, dental caries and periodontal disease in HIV+ patients. Braz J Infect Dis. 2009; 13(1): 13-17

Nittayananta W, Talungchit S, Jaruratanasirikul S, Silpapojakul K, Chayakul P, Nilmanat A et al. Effects of long-term use of HAART on oral health status of HIV infected subjects. J Oral Pathol Med. 2010; 39(5): 397–406. DOI: https://doi.org/10.1111/j.1600-0714.2009.00875.x

Takahashi N, Nyvad B. The role of bacteria in the caries process: ecological perspectives. J Dent Res. 2011; 90(3): 294-303. DOI: https://doi.org/10.1177/0022034510379602

Nelson A, Albert JM, Lombardi G, Wishnek S, Asaad G, Kirchner HL et al. Dental caries and enamel defects in very low birth weight adolescents. Caries Res. 2010; 44(6): 509–518. DOI: https://doi.org/10.1159/000320160

Berkowitz RJ. Mutans streptococci: acquisition and transmission. Pediatr Dent. 2006; 28(2): 106-109.

Navazesh M, Mulligan R, Barrón Y, Redford M, Greenspan D, Alves M et al. A 4-year longitudinal evaluation of xerostomia and salivary gland hypofunction in the Women's Interagency HIV Study participants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003; 95(6): 693-698. DOI: https://doi.org/10.1067/moe.2003.230

American Academy of Pediatric Dentistry. Policy on early childhood caries (ECC): classifications, consequences, and preventive strategies. Pediatr Dent. 2008; 29(Suppl): 39-41

Caufield PW, Griffen AL. Dental caries: an infectious and transmissible disease. Pediatr Clin North Am. 2000; 47(5): 1001-1019.

Sharland M, Di-Zub GC, Ramos JT, Blanche S, Gibb DM; PENTA Steering Committee. PENTA guidelines for the use of antiretroviral therapy in paediatric HIV infection. Pediatric European Network for Treatment of AIDS. HIV Med. 2002; 3(3): 215- 226.

Gaitán-Cepeda LA, Sánchez-Vargas LO, Pavia-Ruz N, Muñoz-Hernández R, Villegas-Ham J, Caballos-Salobreña A. Candida bucal en niños mexicanos con VIH/sida, desnutrición o marginación social. Rev Panam Salud Pública. 2012; 31(1): 48–53.

Vieira AR, de-Souza IPR, Modesto A, Castro GF, Vianna R. Gingival status of HIV+ children and the correlation with caries incidence and immunologic profile. Pediatr Dent. 1998; 20(3): 169-172

Ribeiro AA, Portela M, Souza IP. Relation between biofilm, caries activity and gingivitis in HIV + children. Pesqui Odontol Bras. 2002; 16(2): 144-150

Fine DH, Tofsky N, Nelson EM, Schoen D, Barasch A. Clinical implications of the oral manifestations of HIV infection in children. Dent Clin North Am. 2003; 47(1): 159–174

Szklo M, Nieto J. Epidemiologia intermedia: conceptos y aplicaciones. Madrid: Díaz de Santos; 2003.

Moreno-Altamirano A, López-Moreno S, Corcho-Berdugo A. Principales medidas en epidemiología. Salud Pública Méx. 2000; 42(4): 337-348

Tapia-Granados JA. Medidas de prevalencia y relación incidencia-prevalencia. Organización Panamericana de la Salud. (OPS/OMS). Programa de Publicaciones. Washington. EE. UU. Med Clin (Barc). 1995; 105: 216-218.

Alejo A, Romero J, García-Gestoso ML. Infección por VIH en pediatría: En: Pachón J, Pujol E, Rivero A. Infección por el VIH: guía práctica. 2 ed. Sevilla: Sociedad Andaluza de Enfermedades Infecciosas; 2003. p. 441-468.

Dávila M, Gil M. Manifestaciones orales y caries dental en niños expuestos al virus de inmunodeficiencia humana. Rev Salud Pública. 2011; 13(5): 833-843.

Saldarriaga A, Arango CM, Cossio M, Arenas A, Mejía C, Mejía E et al. Prevalencia de caries dental en preescolares con dentición decidua área Metropolitana del Valle de Aburrá. Rev CES Odont. 2009; 22(2): 27-34

Ismail AI, Sohn W, Tellez M, Willem JM, Betz J, Lepkowski J. Risk indicators for dental caries using the International Caries Detection and Assessment System (ICDAS). Community Dent Oral Epidemiol. 2008; 36(1): 55–68. DOI: https://doi.org/10.1111/j.1600-0528.2006.00369.x

Mendes FM, Braga MM, Oliveira LB, Antunes JL, Ardenghi TM, Bönecker M. Discriminant validity of the International Caries Detection and Assessment System (ICDAS) and comparability with World Health Organization criteria in a cross-sectional study. Community Dent Oral Epidemiol. 2010; 38(5): 398-407. DOI: https://doi.org/10.1111/j.1600-0528.2010.00557.x

Beena JP. Prevalence of dental caries and its correlation with the immunologic profile in HIV‑Infected children on antiretroviral therapy. Eur J Paediatr Dent. 2011; 12(2): 87‑90.

Flaitz C, Wullbrandt B, Sexton J, Bourdon T, Hicks J. Prevalence of orodental findings in HIV infected Romanian children. Pediatr Dent. 2001; 23(1): 44‑50.

Álvarez L, Hermida L, Cuitiño E. Situación de salud oral de los niños uruguayos portadores del virus de la inmunodeficiencia humana. Arch Pediatr Urug. 2007; 78(1): 23-28

Castro GF, Souza IP, Lopes S, Stashenko P, Teles RP. Salivary IgA to cariogenic bacteria in HIV-positive children and its correlation with caries prevalence and levels of cariogenic microorganisms. Oral Microbiol Immunol. 2004; 19(5): 281-288. DOI: https://doi.org/10.1111/j.1399-302x.2004.00152.x

Damle SG, Jetpurwala AK, Saini S, Gupta P. Evaluation of oral health status as an indicator of disease progression in HIV positive children. Pesq Bras Odontoped Clin Integr João Pessoa. 2010; 10(2): 151-156. DOI: https://dx.doi.org/10.4034/1519.0501.2010.0102.0004

Davoodi P, Hamian M, Nourbaksh R, Ahmadi Motamayel F. Oral manifestations related to CD4 lymphocyte count in HIV‑positive patients. J Dent Res Dent Clin Dent Prospects. 2010; 4(4): 115-119. DOI: https://dx.doi.org/10.5681%2Fjoddd.2010.029

Subramaniam P, Kumar K. Cariogenic potential of medications used in treatment of children with HIV infection. Spec Care Dentist. 2014; 34(3): 127-130. DOI: https://doi.org/10.1111/scd.12041

Castro GF, Souza IP, Chianca TK, Hugo R. Evaluation of caries prevention program in HIV+children. Braz Oral Res. 1997; 15: 91‑97.

Rovaris NS, Martins TLG, Traebert J. Oral health condition of children living with HIV. Dent J. 2014; 2: 1-10.

Downloads

Published

2018-05-17

How to Cite

Arango-de la Cruz, M. C., Velasco-Benítez, C. A., & López-López, P. (2018). Dental caries prevalence in children and youths with vertically-transmitted HIV/AIDS from the pediatric HIV clinic (Cali, Colombia) and its relationship with biological factors, 2013. Revista Facultad De Odontología Universidad De Antioquia, 29(2), 273–296. https://doi.org/10.17533/udea.rfo.v29n2a2

Most read articles by the same author(s)

Similar Articles

You may also start an advanced similarity search for this article.