Serum cortisol concentration in the Colombian Creole Horse

Angélica M. Zuluaga; José R. Martínez

doi:10.17533/udea.rccp.v30n3a06

Authors

Angélica M. Zuluaga Equine High Degrees Corporation of Colombia, University of Antioquia
José R. Martínez University of Antioquia

DOI:

https://doi.org/10.17533/udea.rccp.v30n3a06

Keywords:

adrenocorticotrophic hormone, equine, hypothalamic-pituitary-adrenal axis, stress

Abstract

Background: Cortisol is indicative of adaptation to physiological factors, disease and environmental stress in equines. Cortisol recently gained attention for its prognostic value in critical disease and as an indicator of fitness and athletic performance. Objective: To determine baseline serum cortisol (SC) morning concentrations in the Colombian creole horse (CCH). Methods: Blood serum was taken from 62 CCH of both genders with and average age of 8.8 years (± 5.3), which were clinically healthy and had different performance levels. Results: The overall SC average determined by sandwich ELISA was 13.3 ± 7.4 mg/dL. No significant differences were attributed to gender, age, or performance. Conclusion: This concentration can be used as a reference value for CCH maintained in low physical activity.

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Author Biographies

Angélica M. Zuluaga, Equine High Degrees Corporation of Colombia, University of Antioquia

VM, MSc., RICERCA Research group, Equine High Degrees Corporation of Colombia (CAEQUINOS), Medellín, Colombia. Research Line in Medicine and Surgery in Equines (LIMCE), CENTAURO Research Group, Faculty of Agrarian Sciences, University of Antioquia, Medellín, Colombia.

José R. Martínez, University of Antioquia

VMZ, MS, PhD., Research Line in Medicine and Surgery in Equines (LIMCE), CENTAURO Research Group, Faculty of Agrarian Sciences, University of Antioquia, Medellín, Colombia.

References

Alexander SL, Irvine CH. The eff ect of social stress on adrenal axis activity in horses: The importance of monitoring corticosteroid binding globulin capacity. J Endocrinol 1998; 157:425-32.

Armengou L, Jose-Cunilleras E, Ríos J, Cesarini C, Viu J, Monreal L. Metabolic and endocrine profi les in sick neonatal foals are related to survival. J Vet Intern Med 2013; 27:567-575.

Bohák Z, Szabó F, Beckers J, Melo de Sousa N, Kutasi O, Nagy K,Szenci O. Monitoring the circadian rhythm of serum and salivary cortisol concentrations in the horse. Dom Anim Endocrinolo 2013; 45:38-42.

Borer-Weir KE, Menzies-Gow NJ, Bailey SR, Harris PA, Elliott J.Seasonal and annual infl uence on insulin and cortisol results from overnight dexamethasone suppression tests in normal ponies and ponies predisposed to laminitis. Equine Vet J 2013; 45:688-693.

Broom DM. Behaviour and welfare in relation to pathology. Appl Anim Behav Sci 2006; 97:78-83.

Comin A, Veronesi MC, Montillo M, Faustini M, Valentini S, Cairoli F, Prandi A. Hair cortisol level as a retrospective marker of hypothalamic-pituitary-adrenal axis activity in horse foals. Vet J 2012; 194:131-132.

Christensen JW, Beekmans M, Van Dalum M, Van Dierendonck M. Eff ects of hyperflexion on acute stress responses in ridden dressage horses. Physiol Behav 2014; 128:39-45.

Douglas R. Circadian cortisol rhythmicity and equine Cushing ́s-like disease. J Equine Vet Scien 1999; 19:684-687.

CFazio E, Medica P, Aronica V, Grasso L, Ferlazzo A. Circulatingβ-endorphin, adrenocorticotrophic hormone and cortisol levels of stallions before and after short road transport: Stress effect of different distances. Acta Vet Scand 2008; 50:1-7.

CIFerlazzo A, Medica P, Cravana C, Fazio E. Circulating b-endorphin, adrenocorticotropin, and cortisol concentrations of horses before and after competitive show jumping with diff erent fence heights. J Equine Vet Scien 2012; 32:740-746.

Freymond B, Bardou D, Briefer EF, Bruckmaier R, Fouché N, Fleury J, Maigrot L, Ramseyer L, Zuberbühler K, Bachmann I. The physiological consequences of crib-biting in horses in response to an ACTH challenge test. Physiol Behav 2015; 151:121-128.

Gold JR, Divers TJ, Barton MH, Lamb SV, Place NJ, Mohammed HO, Bain FT. Plasma adrenocorticotropin, cortisol, and adrenocorticotropin/cortisol ratios in septic and normal-term foals. J Vet Intern Med 2007; 21:791-796.

Gust DA, Wilson ME, Stocker T, Conrad S, Plotsky PM, Gordon TP. Activity of the hypothalamic-pituitary-adrenal axis is altered by aging and exposure to social stress in female rhesus monkeys. J Clin Endocrinol Metab 2000;85:2556-2563.

Haff ner JC, Juergens T, Yagaan B, Mendjargal A, Yandag G. Mongolian horses: training and racing. J Equine Vet Scien 2004;24:5-8.

Haff ner JC, Fecteau KA, Eiler H, Tserendorj T, Hoff man RM, Oliver JW. Blood steroid concentrations in domestic Mongolian horses. J Vet Diagn Invest 2010; 22:537-543.

Hart KA, Slovis N, Barton M. Hypothalamic-pituitary-adrenal axis dysfunction in hospitalized neonatal foals. J Vet Intern Med 2009; 23:901-912.

Hart KA, Barton MH. Adrenocortical insuffi ciency in horses and foals. Vet Clin Equine 2011; 27:19-34.

Hart KA, Barton MH, Ferguson DC, Berghaus R, Slovis NM, Heusner GL, Hurley DJ. Serum free cortisol fraction in healthy and septic neonatal foals. J Vet Intern Med 2011; 25:345-355.

Irvine CH, Alexander SL. Factors aff ecting the circadian rythm in plasma cortisol concentrations in the horse. Domest Anim Endocrinol 1994; 11:227-238.

Kaneko JJ, Harvey JW, Bruss ML. Clinical biochemistry of domestic animals. 6th ed, Elsevier Inc. 2008, 916p.

Kedzierski W, Cywinska A, Strzelec K, Kowalik S. Changes in salivary and plasma cortisol levels in purebred Arabian horses during race training session. Anim Sci J 2014;85:313-317.

McCue PM. Equine Cushing’s disease. Vet Clin Equine 2002;18:533-543.

Mair TS, Sherlock CE, Boden LA. Cortisol concentrations in horses with colic. Vet J 2014; 201:370-377.

Martos N, Ayala I, Hernández J, Gutiérrez C. Determinación de los niveles plasmáticos de cortisol en diferentes patologías de los équidos. An Vet (Murcia) 2003; 19:129-140.

McGreevy P, Harman A, McLean A, Hawson L. Over-fl exing the horse’s neck: A modern equestrian obsession? J Vet Behav 2010; 5:180-186.

Monk C, Hart K, Berghaus R, Norton N, Moore P, Myrna K. Detection of endogenous cortisol in equine tears and blood at rest and after simulated stress. Vet Ophthalmol 2014; 17:53-60.

Moreno FE. Niveles de cortisol en el neonato equino, en sus primeras 6 horas de vida. Trabajo de grado CES. Medellín, Colombia. 2009; p.44.

Nagel C, Erber R, Bergmaier C, Wulf M, Aurich J, Möstl E, Aurich C. Cortisol and progestin release, heart rate and heart rate variability in the pregnant and postpartum mare, fetus, and newborn foal. Theriogenology 2012; 78:759-767.

Nagel C, Erber R, Ille N, Wulf M, Aurich J, Möstl E, Aurich C. Heart rate and salivary cortisol concentrations in foals at birth. Vet J 2015; 203:250-252.

Nuñez C, Adelman J, Smith J, Gesquiere L, Rubenstein D. Linking social environment and stress physiology in feral mares (Equus caballus): Group transfers elevate fecal cortisol levels. Gen Comparative Endocrinol 2014; 196:26-33.

Pell SM, McGreevy PD. A study of cortisol and beta-endorphin levels in stereotypic and normal thoroughbreds. Appl Anim Behav Sci 1999; 64:81-90.

Place NJ, McGowan CM, Lamb SV, Schanbacher BJ, McGowan T, Walsh DM. Seasonal variation in serum concentrations of selected metabolic hormones in horses. J Vet Intern Med 2010; 24:650-654.

Pritchett LC, Ulibarri C, Roberts MC, Schneidera RK, Sellon DC. Identifi cation of potential physiological and behavioral indicators of postoperative pain in horses after exploratory celiotomy forcolic. Appl Anim Behav Sci 2003; 80:31-43.

Shaba JJ, Behan Braman A, Robinson N.E. Plasma cortisol concentration increases within 6 hours of stabling in RAO-aff ected horses. Equine Vet J 2014; 46:642-644.

Schmidt A, Möstl E, Wehnert CH, Aurich J, Müller J, Aurich CH. Cortisol release and heart rate variability in horses during road transport. Hormon Behav 2010; 57:209-215.

Schreiber, CM, Stewart, AJ; Behrend, EN, Wright J, Kemppainen R, and Busch, KA. Seasonal variation in diagnostic tests for pituitary pars intermedia dysfunction in normal aged geldings. J Vet Intern Med 2008;22:734.

Smiet E, Van Dierendonck M, Sleutjens J, Menheere P, Van Breda E, Boer D, Back W, Wijnberg I, Van der Kolk J. Eff ect of diff erent head and neck positions on behaviour, heart rate variability, and cortisol levels in lunged Royal Dutch Sport horses. Vet J 2014; 202:26-32.