Equine gastric ulcerative syndrome in a population of horses at Antioquia: frequency and risk factors

Authors

  • Angélica M. Zuluaga University of Antioquia
  • Nicolás F. Ramírez University of Antioquia
  • José R. Martínez

DOI:

https://doi.org/10.17533/udea.rccp.v31n2a07

Keywords:

EGUS, endoscopy, equine, ulcer

Abstract

Background: Equine gastric ulcer syndrome (EGUS) has been associated with duration of confinement, grain supplementation, exercise, stress, use of non-steroidal anti-inflammatory drugs, and the gastric microbiome. On the other hand, limited information is available on the risk factors for EGUS in Colombia. Objective: To determine the frequency and risk factors for the presentation of EGUS in several municipalities of Antioquia. Methods: A total of 103 male and female horses were evaluated. Endoscopic samples from different portions of the stomach were taken and subjected to histopathological analysis. Information on management conditions for each animal was also obtained. Descriptive statistics, association analysis and logistic regression were performed. Results: A 69% of the animals presented at least one gastric lesion: 22.3% lesions in the squamous mucosa, 39.2% in the Margo plicatus (MP) and 48.9% in the glandular region. Diet was associated with the presentation of ulcers in the squamous mucosa (p = 0.003). MP ulceration was associated with concentrate feed consumption (p = 0.032). Conclusion: The EGUS frequency is 69%. Consumption of concentrate feed by horses in Antioquia is a critical factor for the development of ulcers in the stomach squamous and glandular regions.

|Abstract
= 273 veces | PDF
= 156 veces|

Downloads

Download data is not yet available.

Author Biographies

Angélica M. Zuluaga, University of Antioquia

MV, MSc, DrSc(st)., Equine Medicine and Surgery Research Line (LIMCE), Centauro Research Group, School of Veterinary Medicine, Faculty of Agrarian Sciences, University of Antioquia (UdeA), Medellín, Colombia.

Nicolás F. Ramírez, University of Antioquia

MV, MS, DrSc., Veterinary Epidemiology and Public Health Research Line, Centauro Research Group, School of Veterinary Medicine, Faculty of Agrarian Sciences, University of Antioquia, Medellín, Colombia.

José R. Martínez

MVZ, MS, PhD., Equine Medicine and Surgery Research Line (LIMCE), Centauro Research Group, School of Veterinary Medicine, Faculty of Agrarian Sciences, University of Antioquia (UdeA), Medellín, Colombia.

References

Al-Mokaddem AK, Ahmed KA, Doghaim RE. Pathology of gastric lesions in donkeys: A preliminary study. Equine Vet J 2015; 47(6):684-688.

Andrews FM, Buchanan BR, Elliot SB, Clariday NA, Edwards LH. Gastric ulcers in horses. JAS 2005; 83(13):18-21.

Aranzales JRM, Cassou F, Andrade BSC, Alves GE. Presence of gastric ulcer syndrome in equine from the military police. Arch Med Vet 2012; 44(2):185-189.

Berschneider H, Blikslager A, Roberts M. Role of duodenal refl ux in nonglandular gastric ulcer disease of the mature horse. Equine Vet J 2010; 31(29):24-29.

Camacho PL, Andrews FM. Equine Gastric Ulcer Syndrome. In: Robinson NE, Sprayberry KA, editors. Robinson’s Current Therapy in Equine Medicine. 7th ed. St. Loius: Elsevier; 2015. p. 280-284.

Cardona J, Vargas M, Blanco R. Frecuencia de patologías gástricas en caballos de trabajo (Equus caballus) en Córdoba, Colombia. Revista Científica 2015; 1(1):386-394.

Cardona Álvarez JA, Arroyave Vanegas V, Zapata Gil AF. Frecuencia de patologías gástricas en burros (Equus africanus asinus) en Córdoba, Colombia. Rev Med Vet 2015b; (31):23-34.

Chameroy KA, Nadeau JA, Bushmich SL, Dinger JE, Hoagland TA, Saxton AM. Prevalence of non-glandular gastric ulcers in horses involved in a university riding program. J Equine Vet Sci 2006; 26(5):207-211.

Crayg TL. Gastric ulcer syndrome in exercising horses fed different types of hay. 54f (Thesis Master of Science). Texas: Texas A & M University; 2007.

Cruz JM, Montoya LM. Toxicity with phenylbutazone in a horse: A case report. Rev CES Med Zootec 2011; 6(1):65-71.

De Souza MV, Bueno Martins da Costa M, De Oliveira Pinto J, Pereira da Silva JC, Dantas Ribeiro Filho J, Lopes Moreira JC. Lesões gástricas em equinos de abatedouro: Avaliação macroscópica e histológica. Ciência Rural 2014; 44(9): 1622-1628.

Hartmann AM, Frankeny RL. A preliminary investigation into the association between competition and gastric ulcer formation in non-racing performance horses. J Equine Vet Sci 2003; 23(12):560-561.

Henneke DR, Potter GD, Kreider JL, Yeates BF. Relationship between condition score, physical measurements and body fat percentage in mares. Equine Vet J 1983;15(4):371-372.

Le Jeune SS, Nieto JE, Dechant JE, Snyder JR. Prevalence of gastric ulcers in Thoroughbred broodmares in pasture: A preliminary report. The Vet J 2009; 181(3):251-255.

Lorenzo-Figueras M, Jones G, Merritt AM. Effects of various diets on gastric tone in the proximal portion of the stomach of horses. Am J Vet Res 2002; 63:1275-1278.

Luthersson N, Harris P, Poulsen J, Soendergaard E, Malmkvist J, Parkin T. High prevalence of glandular ulcer within two large farms in two different countries. In: Proceedings 10th International Equine Colic Research Symposium; July 26-28th 2011.

Luthersson N, Nielsen K. The prevalence and anatomical distribution of equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. Equine Vet J 2009; 41(7):619-624.

Luthersson N, Nielsen KH, Harris P, Parkin TDH. Risk factors associated with equine gastric ulceration syndrome (EGUS) in 201 horses in Denmark. Equine Vet J 2009b; 41(7):625-630.

MacAllister CG, Andrews FM, Deegan E, Ruoff W, Olovson SG. A scoring system for gastric ulcers in the horse. Equine Vet J 1997; 29(6):430-433.

Martineau H, Thompson H, Taylor D. Pathology of gastritis and gastric ulceration in the horse. Part 2: A scoring system. Equine Vet J 2009; 41(7):646-651.

Martínez JR, De Marval CA, Silveira Alves GE. Ulcerative gastric lesions in Brasileiro de hipismo horses. Rev Colomb Cienc Pecu 2014; 27(3):211-219.

Martínez Aranzales JR, Cândido de Andrade BS, Silveira Alves GE. Orally administered phenylbutazone causes oxidative stress in the equine gastric mucosa. J Vet Pharmacol Therap 2015; 38(3):257-264.

McClure SR, Glickman L, Glickman N. Prevalence of gastric ulcer in show horses. Am Vet Med Ass 1999; 215:1130-1133.

Merritt A. Normal equine gastroduodenal secretion and motility. Equine Vet J 1999; 29(29):7-13.

Merritt AM. Appeal for proper usage of the term “EGUS”: Equine gastric ulcer syndrome. Equine Vet J 2009; 41(7): 616-616.

Monki J, Hewetson M, Virtala AMK. Risk factors for equine gastric glandular disease: A case – control study in a Finnish Referral Hospital Population. J Vet Intern Med 2016; 30:1270-1275.

Murray M. How to perform gastroduodenoscopy. In: Proceedings of the Annual Convention of the AAEP; 2002 Dec 4 - 8; Orlando, USA; 2002.

Murray MJ, Eichorn ES. Effects of intermittent feed deprivation, intermittent feed deprivation with ranitidine administration, and stall confinement with ad libitum access to hay on gastric ulceration in horses. Am J Vet Res 1996; 57(11):1599-1603.

Murray MJ, Grodinsky C. Regional gastric pH measurement in horses and foals. Equine Vet J 1989; 21(7):73-76.

Nadeau JA, Andrews FM, Mathew AG, Argenzio RA, Blackford JT, Sohtell M, Saxton AM. Evaluation of diet as a cause of gastric ulcers in horses. Am J Vet Res 2000; 61(7):784-790.

Nieto JE, Snyder JR, Beldomenico P, Aleman M, Kerr JW, Spier SJ. Prevalence of gastric ulcers in endurance horses – a preliminary report. The Vet J 2004; 167(1):33-37.

Orsini JA, Hackett ES, Grenager N. The effect of exercise on equine gastric ulcer syndrome in the Thoroughbred and Standardbred athlete. J Equine Vet Sci 2009; 29(3):167-171.

Pietra M, Morini M, Perfetti G, Spadari A, Vigo P, Peli A. Comparison of endoscopy, histology, and cytokine mRNA of the equine gastric mucosa. Vet Res Commun 2010; 34(suppl 1):121-124.

Reese RE, Andrews FM. Nutrition and dietary management of equine gastric ulcer syndrome. Vet Clin North Am Equine Pract 2009; 25(1):79-92.

Rodrigues NL, Dore M, Doucet M. Validation of a transendoscopic glandular and nonglandular gastric biopsy technique in horses. Equine Vet J 2009; 41:631-635.

Sykes BW, Jokisalo JM. Rethinking equine gastric ulcer syndrome: Part 1 Terminology, clinical signs and diagnosis. Equine Vet Educ 2014; 26(10):543-547.

Sykes BW, Hewetson M, Hepburn RJ, Luttersson N, Tamzali Y. European College of Equine Internal Medicine Consensus Statement – equine gastric ulcer syndrome in adult horses. J Vet Inter Med 2015; 29:1288-1299.

StataCorp. 2011. Stata Statistical Software. Release 12. StataCorp LP, College Station, TX.

Tamzali Y, Marguet C, Priymenko N, Lyazrhi F. Prevalence of gastric ulcer syndrome in high-level endurance horses. Equine Vet J 2011;43(2):141-144.

Videla R, Andrews FM. New perspectives in Equine Gastric Ulcer Syndrome. Vet Clin North Am Equine Pract 2009; 25:283-301.

Wiedner EB, Schmitt DL, Kiso W, Kinchen K, Lindsay WL. Gastroscopy of 30 circus horses. Proc. 10th International Congress of World Equine Veterinary Association (WEVA) 2008; Jan 28 – Feb 1, Moscow: Russia, 2008.

Zuluaga AM, Silveira GE, Martínez JR. Nitric oxide and malondialdehyde in gastric contents and blood in an equine model of gastric ulcer induced by phenylbutazone. Rev Colomb Cienc Pecu 2016; 29:43-50.

Zuluaga AM. Síndrome ulcerativo gástrico equino y helicobacteriosis, en una población de equinos del valle de Aburrá y municipios aledaños (Antioquia). 88f. (Tesis de Maestría). Medellín: Universidad de Antioquia; 2016.

Downloads

Published

2018-06-20

How to Cite

Zuluaga, A. M., Ramírez, N. F., & Martínez, J. R. (2018). Equine gastric ulcerative syndrome in a population of horses at Antioquia: frequency and risk factors. Revista Colombiana De Ciencias Pecuarias, 31(2), 139–149. https://doi.org/10.17533/udea.rccp.v31n2a07

Issue

Section

Original research articles

Similar Articles

> >> 

You may also start an advanced similarity search for this article.