Effect of dietary inclusion of guanidinoacetic acid on broiler performance

  • Kamilla M. Borges Federal University of Goiás
  • Heloisa H. de C. Mello Federal University of Goiás
  • Marcos B. Café Federal University of Goiás
  • Emmanuel Arnhold Federal University of Goiás
  • Hyara P. F. Xavier Federal University of Goiás
  • Helder F. de Oliveira Federal University of Goiás
  • Alessandra G. Mascarenhas Federal University of Goiás
Keywords: additive, chicken, creatine, feed additive, metabolism, nutrition, organ biometry, poultry, guanidinoacetic acid

Abstract

Background: Creatine and its precursor, guanidinoacetic acid (GAA), decrease protein degradation, avoiding amino acid offset to gluconeogenesis. Objective: To evaluate the inclusion of GAA in the pre-initial diet (1 to 7 days) on performance, digestibility, and blood parameters of broilers from one to 21 days of age. Methods: 252 male broiler chickens aged one day were distributed in a completely randomized design with seven replicates and 12 animals per experimental unit. Treatments consisted of a basal diet, and the basal added with 0.10 and 0.20% GAA. Results: From days 1 to 7, a tendency on improved feed conversion (FC) was observed for broilers receiving 0.20% GAA (p<0.10). Between 7 and 14 days, FC improved, as well as a tendency was observed on improved weight gain in animals fed 0.20% GAA. Animals that received 0.20% GAA showed higher blood concentrations of creatine kinase. Blood creatine and blood glucose did not differ between treatments at day six. The assimilation coefficient of crude protein increased during days 3 to 7 for animals receiving 0.20% GAA. On the period between 17 and 21 days, no difference was observed between treatments. Intestinal weight and length did not show significant differences. Conclusion: Dietary inclusion of 0.20% GAA during the pre-initial stage could improve weight gain and feed conversion of broilers between 1 and 14 days of age.

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Author Biographies

Kamilla M. Borges, Federal University of Goiás

https://orcid.org/0000-0003-3187-2015
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Heloisa H. de C. Mello, Federal University of Goiás

http://orcid.org/0000-0002-0312-7424
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Marcos B. Café, Federal University of Goiás

https://orcid.org/0000-0002-1478-8009
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Emmanuel Arnhold, Federal University of Goiás

https://orcid.org/0000-0003-0922-146X
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Hyara P. F. Xavier, Federal University of Goiás

https://orcid.org/0000-0002-7077-2861
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Helder F. de Oliveira, Federal University of Goiás

https://orcid.org/0000-0003-4109-1087
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

Alessandra G. Mascarenhas, Federal University of Goiás

http://orcid.org/0000-0001-8333-0723
Federal University of Goiás, School of Veterinary and Zootechnics, Goiânia, Goiás, Brazil.

References

Barbosa TS, Mori CK, Polónio LB, Ponsano EHG, Ciarlini PC. Perfil bioquímico sérico de galinhas poedeiras na regiao de Aracatuba, SP. Semina: Ciénc Agrár 2011; 32(4):1583-1588. DOI: https://dx.doi.org/10.5433/1679-0359.2011v32n4p1583

Bryant-Angeloni KI. Dietary guanidino acetic acid spares arginine and dietary l-homoserine spares threonine in the chick. [Master of Animal Science] 2010; 1-57. University of Illinois, Illinois, USA.

Deminice R, Portari GV, Vannucchi H, Jordao AA. Effects of creatine supplementation on homocysteine levels and lipid peroxidation in rats. Br J Nutr 2009; 102(1):110-116. DOI: https://doi.org/10.1017/S0007114508162985

DilgerRN,Bryant-AngeloniK, Payne RL,Lemme A, Parsons CM. Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. Poult Sci 2013; 92(1):171-177. DOI: https://doi.org/10.3382/ps.2012-02425

Goncalves FM, Santos VL, Contreira CL, Farina G, Kreuz BS, Gentilini FP, Anciuti MA, Rutz F. Nutricao in ovo: estratégia para nutricao de precisao em sistemas de producao avicola. Arch Zootec 2013; 62 Suppl:45-55. DOI: https://doi.org/10.21071/az.v62i237.1956

Lemme A, Ringel J, Sterk A, Young JF. Supplemental guanidinoacetic acid affect energy metabolism ofbroilers. 16 th European Symposium on Poultry Nutrition; 2007, Strasbourg, Franca. World Poultry Science Association. [access nov 2, 2016]. URL: http://www.cabi.org/Uploads/ animal-science/worlds-poultry-science-association/WPSA-france-2007/29.pdf

Lorsheitter LM, Ferreira TZ, Valle SF, Vieira SL, Bergmann GP, Kindlein L. Comportamento da atividade da creatina quinase em frangos de corte com White striping de diferentes idades e submetidas a dietas distintas. 42° Congresso Bras. de Medicina Veterinária e 1° Congresso Sul-Brasileiro da ANCLIVEPA; 2015; Curitiba, Brasil. [access jan 15, 2017]. URL: http://www. infoteca.inf.br/conbravet/smarty/templates/ arquivos_template/upload_arquivos/acervo/628.pdf

Michiels J, Maertens L, Buyse J, Lemme A, Rademacher M, Dierick NA, De Smet S. Supplementation of guanidinoacetic acid to broiler diets: Effects on performance, carcass characteristics, meat quality, and energy metabolism.PoultSci 2012; 91(2):402-412.DOI: https://doi.org/10.3382/ps.2011-01585

Riccardi RR, Malheiros EB, Boleli IC. Efeito do jejum pós-eclosao sobre pintos de corte provenientes de ovos leves e pesados. Ciénc Anim Bras 2009; 10(4):1013-1020. DOI: https:// www.revistas.ufg.br/vet/article/view/1194

Rostagno HS, Albino LFT, Donzele JL, Gomes PC, Oliveira RF, Lopes DC, Ferreira AS, Barreto SLT, Euclides RF. Tabelas brasileiras para aves e suinos: composicao de alimentos e exigéncias nutricionais. Vicosa, Minas Gerais (BR): Editora da Universidade Federal de Vicosa; 2011.

Sakomura NK, Rostagno HS. Métodos de pesquisa em nutricao de monogástricos. Jaboticabal, Sao Paulo (BR): FUNEP; 2007.

Saukas TN. Variáveis hematológicas e bioquímicas em aves (Gallus gallus, LINNAEUS, 1758) inoculadas com amostras vacinal e de campo do virus da doenca infecciosa bursal. [Doctoral Thesis] 1993. Faculdade de

Medicina Veterinária e Zootecnia. Universidade Estadual Paulista, Sao Paulo, Brasil.

Schmidt EMS, Locatelli-Dittrich R, Santin E, Paulillo AC. Patologia clinica em aves de producao - Uma ferramenta para monitorar a sanidade avicola - Revisao. Arch Vet Sci 2007; 12(3):9-20. DOI: http://dx.doi.org/10.5380/avs.v12i3.10906

Setoue M, Ohuchi S, Morita T, Sugiyama K. Hyperhomocysteinemia induced by guanidinoacetic acid is effectively suppressed by choline and betaine in rats. Biosci Biotechnol Biochem 2008; 72(7):1696-1703. DOI: https://doi.org/10.1271/bbb.70791

Silva JD, Queiroz AC. Análise de alimentos -métodos químicos e biológicos. 3a ed. Vicosa, Minas Gerais (BR): Editora da Universidade Federal de Vicosa; 2009.

Viola ES, Vieira SL, Torres CA, Freitas DM, Berres J. Desempenho de frangos de corte sob suplementacao com ácidos lático, fórmico, acético e fosfórico no alimento ou na água. R Bras Zootec 2008; 37(2):296-302. DOI: https://doi.org/10.1590/S1516-35982008000200016

Wyss M, Kaddurah-Daouk R. Creatine and creatinine metabolism. Physiol Rev 2000; 80(3):1107-1213. DOI: https://doi.org/10.1152/ physrev.2000.80.3.1107

Yair R, Shahar R, Uni Z. Prenatal nutritional manipulation by in ovo enrichment influences bone structure,composition, and mechanical properties. J Anim Sci 2013; 91(6):2784-2793. DOI: https://doi.org/10.2527/jas.2012-5548

Published
2020-07-13
Section
Original research articles