The Effect of Powdered Micronutrients on the Hematologic Values and Nutritional Status of Healthy Preschoolers. Medellín, 2013

Authors

  • Juliana Orozco C. CES University
  • Cristian Vargas G. CES University
  • Maylen L. Rojas B. CES University
  • Ana Milena Herrera T. Co-operative University of Colombia
  • Liliana Montoya V. CES University
  • Juliana Sánchez G. CES University
  • Javier Chica P. Premex S.A.
  • Oscar Villada O. San Vicente de Paúl Hospital Foundation
  • Alejandro Díaz D. CES University

DOI:

https://doi.org/10.17533/udea.rfnsp.v33n2a03

Keywords:

preschooler, foods, anthropometry, heme, micronutrients

Abstract

Micronutrient deficiencies are a common public health problem, particularly in developing countries. Vitamin A, iron and iodine deficiencies are the most prevalent. To reduce these, many strategies such as food fortification can be implemented. Objective: to assess the effect of a diet fortified with powdered micronutrients on the nutritional status and hematological values of healthy preschoolers. Methodology: a randomized, triple-blind, placebo-controlled trial conducted with 90 healthy preschoolers who were given 1g of powdered micronutrients per day with 12.5 mg of iron (ferrous fumarate). The levels of hemoglobin, serum ferritin, transferrin, folic acid and the nutritional indicators were measured before and after nine weeks. Results: for the group receiving powdered micronutrients, hemoglobin concentration decreased from 12.80 g / dL to 12.10 g / dL (p = 0.000), whereas the placebo group showed no change (p = 0.639); likewise, transferrin decreased significantly only for the powdered micronutrients group (p = 0.004); the ferritin level showed no difference between groups or inside any of them. Adverse reactions were similar for both groups:two children had nausea and two abdominal pain. There were no statistically significant differences. Conclusions: fortifying the individuals' diet with the powdered micronutrients used in this study for nine weeks did not improve the hematological levels or the nutritional status of the healthy preschoolers. Additionally, the fortified foods were well tolerated by the children.

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Author Biographies

Juliana Orozco C., CES University

Dietitian nutritionist. Master in Epidemiology. Research group in Basic Sciences. CES University, Medellín, Colombia.

Cristian Vargas G., CES University

Surgeon. Master in Epidemiology. Research Group in Basic Sciences, CES University, Medellín, Colombia.

Maylen L. Rojas B., CES University

Professional in Health Information Systems Management. Master in Epidemiology. CES University, Medellín, Colombia.

Ana Milena Herrera T., Co-operative University of Colombia

Surgeon, Master in Epidemiology, Ph.D in Pathology, Post-Doctorate in Cancer, Co-operative University of Colombia, Villavicencio. Colombia.

Liliana Montoya V., CES University

Technologist in Health Information Systems. Professional in Health Information Systems Management. Master in Epidemiology. Professor of the Faculty of Medicine, Postgraduate Public Health Coordinator, CES University. Researcher in the Public Health Observatory Group. Medellín Colombia.

 

Juliana Sánchez G., CES University

Dentist. Master in Epidemiology. Epidemiology and Biostatistics Group. CES University, Medellin, Colombia.

Javier Chica P., Premex S.A.

Zootecnista, Master in animal production, emphasis on animal nutrition. Manager of Research and Measurement. Premex S.A, Medellín, Colombia.

Oscar Villada O., San Vicente de Paúl Hospital Foundation

Surgeon. Master in Epidemiology. San Vicente de Paúl Foundation, Medellín, Colombia.

Alejandro Díaz D., CES University

Physician, Pediatrician specializing in infectious diseases. CES University, Medellín, Colombia.

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Published

2015-05-15

How to Cite

1.
Orozco C. J, Vargas G. C, Rojas B. ML, Herrera T. AM, Montoya V. L, Sánchez G. J, Chica P. J, Villada O. O, Díaz D. A. The Effect of Powdered Micronutrients on the Hematologic Values and Nutritional Status of Healthy Preschoolers. Medellín, 2013. Rev. Fac. Nac. Salud Pública [Internet]. 2015 May 15 [cited 2025 Dec. 5];33(2):161-70. Available from: https://revistas.udea.edu.co/index.php/fnsp/article/view/18826

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Research