Reinfection or Reactivation of Pulmonary Tuberculosis (PT)? A Diagnostic Challenge
DOI:
https://doi.org/10.17533/udea.rfnsp.v33n3a12Keywords:
tuberculosis, molecular biology, multi-drug resistanceAbstract
The recurrence of tuberculosis (TB) has become a diagnostic challenge because, in many instances, the immune system may be altered. Such is the case of immunodeficiencies. There is another scenario in which a different strain of Mycobacterium tuberculosis may come from the outside and cause the disease again in the patient, regardless of their immune status. This happens most frequently to immunocompetent patients. The ratio of reinfection with the immunosuppressive condition of the patient takes into account the prevalence and incidence behavior of the disease. In the case of HIV, the higher the prevalence, the higher the incidence of tuberculosis, which means there is infection coexistence. The current challenge indicates that there must be greater suspicion in certain cases deserving further study through additional techniques. Additionally, studies should search for reactivation or reinfection and take into account the clinical, social and economic impact that this generates.
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