¿Reinfección o reactivación en la tuberculosis pulmonar? Un reto diagnóstico

Mateo Zuluaga G.

doi:10.17533/udea.rfnsp.v33n3a12

Autores

Mateo Zuluaga G. Universidad Pontificia Bolivariana

DOI:

https://doi.org/10.17533/udea.rfnsp.v33n3a12

Palavras-chave:

tuberculose, biologia molecular, multidroga-resistência

Resumo

A recorrência da tuberculose (TB) torna-se um desafio diagnóstico, pois em muitos casos o sistema imune pode estar alterado como no caso das imunodeficiências. Existe outro cenário no qual uma cepa diferente da Mycobacterium tuberculosis pode chegar do exterior e causar novamente a doença no paciente, independente do seu estado imune, sendo o caso mais frequente em pacientes imunocompetentes. A relação de reinfecção com o estado imunossupressor do paciente leva em consideração o comportamento de prevalência e incidência da doença; no caso do HIV quanto maior for prevalência maior será a incidência da tuberculose, por isto fala-se de coexistência da infecção. O desafio atual alerta a se ter uma maior suspeita diante de certos casos que mereçam ser estudados de maneira profunda através de outras técnicas, procurando encontrar se se trata de uma reativação ou de uma reinfecção, considerando o impacto clínico, social e econômico gerado.

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Biografia do Autor

Mateo Zuluaga G., Universidad Pontificia Bolivariana

Estudante internado Faculdade de Medicina, Universidade Pontifícia Bolivariana, Medellín, Colômbia. Monitor de Microbiologia e Parasitologia I, Membro de grupos de pesquisa Endocardio (Clínica Cardiovid), Grupo de pesquisa HPTU, Grupo de pesquisa GIERI (Hospital Pablo Tobon Uribe) Biologia de sistemas (UPB), assessor e avaliador de projetos de feira explora.

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