Uropathogenic escherichia coli resistant to multiple antibiotics: a public health problem
DOI:
https://doi.org/10.17533/udea.rfnsp.26633Abstract
La infección del tracto urinario (ITU) se ha clasificado como una de las principales causas de consulta médica a nivel comunitario y hospitalario. Escherichia colies el microorganismo más frecuente responsable del 75-85% de este tipo de enfermedades; estas bacterias presentan resistencia a diferentes tipos de antibióticos, especialmente a los de uso clínico, entre ellos a cefalosporinas de tercera generación, aminoglicósidos, sulfas y quinolonas, mostrando un fenotipo de multirresistencia; además posee varios genes de virulencia y patogenicidad, los cuales junto con una serie de características necesarias en el hospedero facilitan el desarrollo de esta patología.
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References
(1). Andersson DI, Hughes D. Antibiotic resistance and its cost: is it possible to reverse resistance? Nature Reviews Microbiology 2010; 8(4) :260-271. DOI: https://doi.org/10.1038/nrmicro2319
(2). Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Dis Mon 2003; 49 (2): 53-70. DOI: https://doi.org/10.1016/S0011-5029(03)90000-9
(3). Peirano G, Pitout JD. Molecular epidemiology of Escherichia coli producing ctx-m beta-lactamases: the worldwide emergence of clone ST131 O25:H4. Int J Antimicrob Agents. 2010; 35 (4): 316- 321. DOI: https://doi.org/10.1016/j.ijantimicag.2009.11.003
(4). Eileen R. Choffnes DAR, and Alison Mack, Rapporteurs. Antibiotic Resistance: Implications for Global Health and Novel Intervention Strategies. Washington DC: National Academies Press; 2010.
(5). Lederberg J. Infectious history. Science 2000; 288 (5464): 287- 293. DOI: https://doi.org/10.1126/science.288.5464.287
(6). Courvalin P. Predictable and unpredictable evolution of antibiotic resistance. J Intern Med 2008; 264 (1): 4-16. DOI: https://doi.org/10.1111/j.1365-2796.2008.01940.x
(7). Tafur J, Villegas M. Mecanismos de resistencia a los antibióticos en bacterias gram negativas. Asociación Colombiana de Infectología 2008; 12(3): 217-226.
(8). Marciano DC, Karkouti OY, Palzkill T. A fitness cost associated with the antibiotic resistance enzyme SME-1 beta-lactamase. Genetics 2007; 176 (4): 2381-2392. DOI: https://doi.org/10.1534/genetics.106.069443
(9). Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev 2010; 74 (3): 417-433. DOI: https://doi.org/10.1128/MMBR.00016-10
(10). Davies J, Spiegelman GB, Yim G. The world of subinhibitory antibiotic concentrations. Curr Opin Microbiol 2006; 9 (5): 445-453. DOI: https://doi.org/10.1016/j.mib.2006.08.006
(11). Kohanski MA, DePristo MA, Collins JJ. Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Molecular cell 2010; 37 (3): 311-320. DOI: https://doi.org/10.1016/j.molcel.2010.01.003
(12). Creager AN. Adaptation or selection? Old issues and new stakes in the postwar debates over bacterial drug resistance. Stud Hist Philos Biol Biomed Sci 2007; 38 (1): 159-190. DOI: https://doi.org/10.1016/j.shpsc.2006.06.016
(13). Koonin EV, Wolf YI. Is evolution Darwinian or/and Lamarckian? Biol Direct 2009; 4: 42. DOI: https://doi.org/10.1186/1745-6150-4-42
(14). Doolittle WF, Bapteste E. Pattern pluralism and the Tree of Life hypothesis. Proc Natl Acad Sci U S A 2007; 104 (7): 2043-2049. DOI: https://doi.org/10.1073/pnas.0610699104
(15). Raoult D. The post-Darwinist rhizome of life. Lancet 2010; 375 (9709): 104-105. DOI: https://doi.org/10.1016/S0140-6736(09)61958-9
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