Seroprevalencia de anticuerpos contra encefalitis esquina venezolana en la población expuesta a la epizootia en el departamento de Casanare, Colombia.
DOI:
https://doi.org/10.17533/udea.rfnsp.964Keywords:
Encefalitis equina venezolana, epizootia, ciclo enzoótico, ciclo epienzoótico, seroprevalencia.Abstract
En el departamento de Casanare, Colombia, entre los meses de mayo y agosto de 1998, se presento una epizootia de encefalitis equina venezolana (EEV) con una incidencia del 8%, en 6 municipios, sin presentación de casos clínicos en humanos. Se diseñó un estudio seccional cruzado con el fin de establecer la seroprevalencia en humanos y explorar factores de riesgo. Se realizó un muestreo aleatorio simple de 304 personas de los 6 municipios afectados, estimando una seroprevalencia de 2,4% con un IC 95% = 1,0 - 4,8 sin encontrar posible asociación con el sexo, edad, antecedentes de vacunación, ocupación y zona afectada. Este comportamiento difiere de la virulencia y afección humana del brote de la Guajira en 1995.
El estudio permitió georreferenciar los casos de la enfermedad en équidos y ubicar los casos seroprevalentes de humanos que determinan la circulación histórica del virus en sus dos ciclos y que convierten el departamento de Casanare, por sus condiciones generales, en foca de investigación del problema
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