Bacterial Meningitis in Neonates: A Multicenter Descriptive Study in the City of Medellín, Colombia

Autores/as

  • Yulieth Alexandra Zúñiga Universidad de Antioquia, Medellín, Colombia https://orcid.org/0000-0002-3703-1754
  • Luis Felipe Vélez-Martínez Universidad de Antioquia, Medellín, Colombia https://orcid.org/0000-0003-3579-566X
  • Leidy Carolina López Universidad de Antioquia, Medellín, Colombia https://orcid.org/0000-0003-0199-9760
  • Claudia Patricia Beltrán Universidad de Antioquia, Medellín, Colombia
  • William Cornejo-Ochoa Universidad de Antioquia, Medellín, Colombia

DOI:

https://doi.org/10.17533/udea.iatreia.192

Palabras clave:

Antiinfecciosos, Meningitis Bacteriana, Pleocitosis, Recién Nacido, Registros Médicos, Sepsis, Anti-Infective Agents

Resumen

Introduction: Bacterial meningitis is a severe infection requiring early empirical therapeutic intervention. In Colombia, there is limited information regarding this disease in the neonatal stage, necessitating up-to-date data to guide timely antibiotic therapy.
Objective: To describe the clinical, microbiological, and epidemiological characteristics of neonatal bacterial meningitis in three hospital centers in the city of Medellín during the years 2010 to 2019.
Methods: A descriptive study was conducted using electronic medical records of newborns treated in three hospitals in Medellín from 2010 to 2019. Clinical records with a discharge diagnosis of bacterial meningitis and corresponding microbiological isolation were reviewed. Data were extracted from SAP® and Servinte Clinical Suite Enterprise® and recorded in a Google® spreadsheet.
Results: A total of 125 records with a diagnosis of neonatal meningitis were reviewed with only 42 cases meeting microbiological isolation criteria.The mean gestational age was 35 weeks, and the most frequentlyisolated pathogens were Escherichia coli (40.5%) and Streptococcus agalactiae (40.5%). In 71.4% of cases, the meningitis was classified as late-onset according to age. Primary symptoms included irritability (56.1%) and fever (48.8%).
Conclusions: The most common causative agents identified in this population were S. agalactiae and E. coli. Principal symptoms were irritability and fever. A significant proportion of neonates did not present suggestive symptoms of central nervous system infection. Additionally, prematurity was predominant in the studied population.

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Biografía del autor/a

Yulieth Alexandra Zúñiga , Universidad de Antioquia, Medellín, Colombia

Estudiante de pregrado en Microbiología y Bioanálisis. Universidad de Antioquia. Pediaciencias, Departamento de Pediatría, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia

Luis Felipe Vélez-Martínez, Universidad de Antioquia, Medellín, Colombia

Estudiante de pregrado en Microbiología y Bioanálisis. Universidad de Antioquia. Pediaciencias, Departamento de Pediatría, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Leidy Carolina López, Universidad de Antioquia, Medellín, Colombia

Estudiante de pregrado en Microbiología y Bioanálisis. Universidad de Antioquia. Pediaciencias, Departamento de Pediatría, Facultad de Medicina, Universidad de Antioquia. Medellín, Colombia.

Claudia Patricia Beltrán , Universidad de Antioquia, Medellín, Colombia

Docente Departamento de Pediatría, Universidad de Antioquia. Pediatra especialista en infectología. Clínica El Rosario. Clínica del Prado-Grupo Quirón Salud. Medellín, Colombia. 

William Cornejo-Ochoa, Universidad de Antioquia, Medellín, Colombia

Especialista en Neurología Infantil. Especialista en Neurología Clínica. Magíster en Epidemiología. Director Grupo de Investigación Pediaciencias. Universidad de Antioquia. Medellín, Colombia.

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Publicado

20-09-2022

Cómo citar

1.
Zúñiga YA, Vélez-Martínez LF, López-García LC, Beltrán-Arroyave CP, Cornejo-Ochoa JW. Bacterial Meningitis in Neonates: A Multicenter Descriptive Study in the City of Medellín, Colombia. Iatreia [Internet]. 20 de septiembre de 2022 [citado 26 de febrero de 2024];36(4). Disponible en: https://revistas.udea.edu.co/index.php/iatreia/article/view/348867

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