Study and clinical management of child household contacts of tuberculosis patients, Medellin 2010-2011

Authors

  • Dione Benjumea Bedoya University of Antioquia
  • María Patricia Arbeláez Montoya University of Antioquia

DOI:

https://doi.org/10.17533/udea.iatreia.v28n2a04

Keywords:

isoniazid, latent tuberculosis, preschool, tuberculosis

Abstract

Introduction: Treatment for latent tuberculosis decreases the risk of this infection in children who are household contacts of patients with such disease.

Objective: To describe the study and clinical management of children under 5 years of age who were household contacts of pulmonary tuberculosis patients in Medellin, Colombia during the period 2010-2011.

Materials and methods: Cross-sectional study. The relationship between socio- demographic and clinical characteristics, and the management of children and index cases was explored.

Results: 28.6% were studied with at least chest X rays and tuberculin skin test. Of those who attended clinical evaluation, 7.9% had active tuberculosis; out of the remaining, 19.4% received treatment for latent tuberculosis. The probability of being studied was higher if the household contact had contributory or subsidized health coverage (adjusted OR: 6.7; 95% CI: 1.5-30.5). The opportunity to receive treatment for latent tuberculosis was related to the tuberculin skin test (adjusted OR: 40.2; 95% CI: 2.59-623.6).

Conclusion: The household contacts had not been adequately studied, and did not receive the right treatment, so the prevalence of active tuberculosis among them did not decrease. It is necessary to establish a standardized protocol for the management of children living under similar conditions, and to monitor its implementation.

|Abstract
= 272 veces | PDF (ESPAÑOL (ESPAÑA))
= 134 veces|

Downloads

Download data is not yet available.

Author Biographies

Dione Benjumea Bedoya, University of Antioquia

Doctoral student in Public Health, University of Antioquia, Medellín, Colombia.

María Patricia Arbeláez Montoya, University of Antioquia

Dean, National School of Public Health, University of Antioquia, Medellín, Colombia.

References

(1.) Dye C, Floyd K. Tuberculosis. En: Jamison DT, Breman JG, Measham AR, Alleyne G, Claeson M, DB Evans, et al., editors. Disease Control Priorities in Developing Countries. 2° ed. Washington (DC): World Bank; 2006. p. 289-309.

(2.) World Health Organization. Stop TB Dept. Implementing the WHO Stop TB Strategy: a handbook for WHO; 2008. p. 46-59.

(3.) World Health Organization. Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children. Geneva: WHO; 2006. p. 4-9, 16-19.

(4.) New Jersey Medical School National Tuberculosis Center. Management of Latent Tuberculosis Infection in Children and Adolescents: A Guide for the Primary Care Provider [Internet]. New Jersey: New Jersey Medical School; 2009. p. 6-11. Available from: http://www.umdnj.edu/globaltb/downloads/products/PediatricGuidelines%20%28Screen%29.pdf

(5.) Colombia. Ministerio de la Protección Social. Guía 11: Guía de Atención de la Tuberculosis Pulmonar y Extrapulmonar. En: Guías de promoción de la salud y prevención de enfermedades en la salud pública [Internet]. Bogotá: Scripto; 2007. p. 19-105. Disponible en: http://www.minsalud.gov.co/Documentos%20y%20Publicaciones/GUIAS%20DE%20ATENCION%20-TOMO%20DOS.pdf

(6.) Millard PS, Wilcosky TC, Reade-Christopher SJ, Weber DJ. Isoniazid-eelated fatal hepatitis. West J Med. 1996 Jun;164(6):486-91.

(7.) Centers for Disease Control and Prevention. Severe isoniazid-associated liver injuries among persons being treated for latent tuberculosis infection - United States, 2004-2008. MMWR Morb Mortal Wkly Rep. 2010 Mar;59(8):224-9.

(8.) Banu Rekha VV, Jagarajamma K, Wares F, Chandrasekaran V, Swaminathan S.Contact screening and chemoprophylaxis in India’s Revised Tuberculosis Control Programme: a situational analysis. Int J Tuberc Lung Dis. 2009 Dec;13(12):1507-12.

(9.) Van Wyk SS, Hamade H, Hesseling AC, Beyers N, Enarson DA, Mandalakas AM.Recording isoniazid preventive therapy delivery to children: operational challenges. Int J Tuberc Lung Dis. 2010 May;14(5):650-3.

(10.) del Corral H, París SC, Marín ND, Marín DM, López L, Henao HM, et al. IFNγ Response to Mycobacterium tuberculosis, Risk of Infection and Disease in Household Contacts of Tuberculosis Patients in Colombia. PLoS One [Internet]. 2009 Dec;4(12):e8257. Available from: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0008257

(11.) Claessens NJ, Gausi FF, Meijnen S, Weismuller MM, Salaniponi FM, Harries AD. Screening childhood contacts of patients with smear-positive pulmonary tuberculosis in Malawi. Int J Tuberc Lung Dis. 2002 Apr;6(4):362-4.

(12.) van Wyk SS, Reid AJ, Mandalakas AM, Enarson DA, Beyers N, Morrison J, et al. Operational challenges in managing Isoniazid Preventive Therapy in child contacts: a high-burden setting perspective. BMC Public Health. 2011 Jul;11:544.

(13.) Cuervo J. Características, resultados del tratamiento antituberculoso y factores determinantes de abandono en casos nuevos tratados en las instituciones de salud que notifican al programa de prevención y control de tuberculosis de la Secretaría Distrital de Salud de Santafé de Bogotá durante 1999. [Tesis Ma-gíster en epidemiología clínica]. Bogotá: Pontificia Universidad Javeriana. Facultad de Medicina; 2001.

(14.) Colombia. Ministerio de la Protección Social. Tomo V: Prestación de Servicios de Salud. En: Análisis de la Situación de Salud en Colombia, 2002-2007 [In-ternet]. Bogotá: Imprenta Nacional de Colombia; 2010. Disponible en: http://www.minsalud.gov.co/Documentos%20y%20 Publicaciones/ASIS-Tomo%20V--Prestaci%C3%B3n%20de%20servicios%20de%20sa-lud.pdf

(15.) Arbeláez MP. La reforma del sector salud y el control de la tuberculosis en Colombia. En: Yadón ZE, Gürt-ler RE, Tobar F, AC Medici, editores. Descentralización y gestión del control de las enfermedades transmisibles en América Latina. Buenos Aires: OPS. 2006. p. 115–29.

(16.) Hernández M. Reforma sanitaria, equidad y derecho a la salud en Colombia. Cad Saúde Pública. 2002 Jul-Ago;18(4):991–1001.

(17.) Quintana S. El acceso a los servicios de salud en Colombia 2002 [Internet]. España: Médicos Sin Fronteras; 2002. [consultado 2012 feb 3]. Disponible en: http://www.disaster-info.net/desplazados/informes/msf/accesosaludcol.htm

(18.) Marais BJ, van Zyl S, Schaaf HS, van Aardt M, Gie RP, Beyers N. Adherence to isoniazid preventive chemotherapy: a prospective community based study. Arch Dis Child. 2006 Sep;91(9):762-5.

(19.) van Zyl S, Marais BJ, Hesseling AC, Gie RP, Beyers N, Schaaf HS. Adherence to anti-tuberculosis chemoprophylaxis and treatment in children. Int J Tuberc Lung Dis. 2006 Jan;10(1):13-8.

(20.) Véjar Mourgués L, Henao R M. Adherencia a quimio-profilaxis de niños chilenos expuestos a tuberculosis del adulto. Rev Chil Enferm Respir. 2006;22(3):164-7.

Published

2015-04-08

How to Cite

1.
Benjumea Bedoya D, Arbeláez Montoya MP. Study and clinical management of child household contacts of tuberculosis patients, Medellin 2010-2011. Iatreia [Internet]. 2015 Apr. 8 [cited 2025 Feb. 23];28(2):137-4. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/17862

Issue

Section

Original research