Tumor Necrosis Factor (TNF) or Cachectin

Authors

  • Jorge Eliécer Ossa Londoño Universidad de Antioquia

DOI:

https://doi.org/10.17533/udea.iatreia.3336

Keywords:

Tumor Necrosis Factor, Cachectin, Lymphotoxin, Endotoxic Shock

Abstract

This is a review of the 1986-1987 Literature on the Tumor Necrosis Factor (TNF) or Cachectin, emphasizing functional and molecular differences among TNF alpha, Iymphotoxin or TNF beta and Cachectin. Mechanisms of shock, tumor necrosis and cachexia are discussed. In vivo and in vitro antitumoral properties of TNF are indicated, as well as some experimental therapeutic regimens. These facts allow the suggestion that TNF might become an important aid for Immunotherapy of cancer in humans.

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Author Biography

Jorge Eliécer Ossa Londoño, Universidad de Antioquia

Profesor, Departamento. de Microbiología y Parasicología, Facultad de Medicina, UnIversidad de Antioquia, Medellín, Colombia.

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Published

1988-02-26

How to Cite

1.
Ossa Londoño JE. Tumor Necrosis Factor (TNF) or Cachectin. Iatreia [Internet]. 1988 Feb. 26 [cited 2025 Feb. 2];1(2):pág. 114-120. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/3336

Issue

Vol. 1 No. 2

Section

Case reports

License

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