Panuveitis due to Lyme disease in a Colombian patient: case report
DOI:
https://doi.org/10.17533/udea.iatreia.46Keywords:
Borrelia burgdorferi, borreliosis, Lyme disease, ixodes, panuveitis, uveitisAbstract
Lyme Disease is a zoonosis transmitted by arthropods that has been described with more frequency in endemic zones of meridional countries. Its clinical manifestations vary according to the clinical stage of the disease. The eye can be affected in many forms including the involvement of the ocular surface and the posterior segment, with more severe inflammation of the retina and the choroid. We present a case of a 72-year male with a recent trip to EEUU who complained of decreasing vision in his left eye had clinical signs of non-granulomatous panuveitis with macular edema and retinal vasculitis. Lyme disease was confirmed with positive antibodies in blood and Western blot test, and the patient was successfully treated using oral Doxycycline. His visual acuity improved and had a resolution of the intraocular inflammation after the specific treatment.
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(1.) Schwartz AM, Hinckley AF, Mead PS, Hook SA, Kugeler KJ. Surveillance for Lyme Disease - United States, 2008-2015. MMWR Surveill Summ. 2017;10;66(22):1-12. DOI 10.15585/mmwr.ss6622a1.
(2.) Borchers AT, Keen CL, Huntley AC, Gershwin ME. Lyme disease: a rigorous review of diagnostic criteria and treatment. J Autoimmun. 2015;57:82-115. DOI 10.1016/j.jaut.2014.09.004.
(3.) Hu LT. Lyme Disease. Ann Intern Med. 2016 May 3;164(9):ITC65-ITC80. DOI 10.7326/AITC201605030.
(4.) Bush LM, Vazquez-pertejo MT. Disease-a-Month Tick borne illness- Lyme disease. Dis Mon. 2018;64(5):195-212. DOI 10.1016/j.disamonth.2018.01.007.
(5.) Mora P, Carta A. Ocular manifestations of Lyme borreliosis in Europe. Int J Med Sci. 2009;6(3):124-5. DOI 10.7150/ijms.6.124.
(6.) Mikkila H, Seppala I, Leirisalo-repo M, Immonen I, Karma A. The etiology of uveitis: The role of infections with
special reference to Lyme borreliosis. Acta Ophthalmol. 1997;75(6):716-9. DOI 10.1111/j.1600-420.1997.tb00637.x.
(7.) Breeveld J, Rothova A, Kuiper H. Intermediate uveitis and Lyme borreliosis. Br J Ophthalmol. 1992;76(3):181-
DOI 10.1136/bjo.76.3.181.
(8.) Bodaghi B. Ocular manifestations of Lyme disease. Med Mal Infect. 2007;37(7-8):518-22. DOI 10.1016/j.medmal.2006.01.016.
(9.) Mahne J, Kranjc BS, Strle F, Ružić-Sabljić E, Arnež M. Panuveitis caused by Borrelia burgdorferi sensu lato
infection. Pediatr Infect Dis J. 2015;34(1):102-4. DOI 10.1097/INF.0000000000000473.
(10.) Cutler SJ, Rudenko N, Golovchenko M, Cramaro WJ, Kirpach J, Savic S, et al. Diagnosing Borreliosis. Vector Borne Zoonotic Dis. 2017;17(1):2-11. DOI 10.1089/vbz.2016.1962.
(11.) Mahne J, Kranjc BS, Strle F, Ružić-Sabljić E, Arnes M. Panuveitis caused by Borrelia Burgdorferi Sensu Lato infection. Pediatr Infect Dis J. 2015 Ene;34 (1):102-4. DOI 10.1097/INF.0000000000000473.
(12.) De-la-Torre A1, López-Castillo CA, Rueda JC, Mantilla RD, Gómez-Marín JE, Anaya JM. Clinical patterns of uveitis in two ophthalmology centres in Bogota, Colombia. Clin Exp Ophthalmol. 2009;37(5):458-66. DOI 10.1111/j.1442-9071.2009. 02082.x.
(13.) Bernard Q, Jaulhac B, Boulanger N. Skin and arthropods: an effective interaction used by pathogens in vector-borne diseases. Eur J Dermatol. 2015 Apr;25 Suppl 1:18-22. DOI 10.1684/ejd.2015.2550.
(14.) Fajardo M, Fajardo Luis. La enfermedad de Lyme. Acta Médica Colombiana. 1994:19(4).
(15.) Halperin JJ. Neuroborreliosis. J Neurol. 2017 Jun;264(6):1292-97. DOI 10.1007/s00415-016-8346-2.
(16.) Mantilla-Flórez YF, Faccini-Martínez ÁA, Pérez-Díaz CE. American woman with early Lyme borreliosis diagnosed in a Colombian hospital. Travel Med Infect Dis. 2017;16:72-3. DOI 10.1016/j.tmaid.2017.01.005.
(17.) Zuluaga-de Cadena A, Boteri F, Herrera WL, Robledo J, Cortés A, Lotero MC. Enfermedad de Lyme: un caso comprobado en Colombia. Rev. CES Medicina. 2000;14(2).
(18.) Pleyer U, Priem S, Bergmann L, Burmester G, Hartmann C. Detection of Borrelia burgdorferi DNA in urine of patients with ocular Lyme borreliosis. Br J Ophthalmol. 2001;85(5):552-5. DOI 10.1136/bjo.85.5.552.
(19.) Mygland A. Could it be Lyme neuroborreliosis? Tidsskr Nor Laegeforen. 2017;137(2):86. DOI 10.4045/tidsskr.16.1032.
(20.) Pleyer U, Priem S, Bergmann L, Burmester G, Hartmann C. Detection of Borrelia burgdorferi DNA in urine of patients with ocular Lyme borreliosis. Br J Ophthalmol. 2001;85(5):552-5. DOI 10.1136/bjo.85.5.552.
(21.) Mattar S, López Valencia G. Searching for Lyme Disease in Colombia: a Preliminary Study on the Vector. J Med Entomol. 1998;35(3):324-6.
(22.) Palacios R, Osorio LE, Giraldo LE, Torres AJ, Philipp MT, Ochoa MT. Positive IgG Western Blot for Borrelia burgdorferi in Colombia. Mem Inst Oswaldo Cruz. 1999;94(4):499-503. DOI 10.1590/S0074-02761999000400013.
(23.) Miranda J, Mattar S, Perdomo K, Palencia L. Seroprevalencia de Borreliosis, o Enfermedad de Lyme, en una Población Rural Expuesta de Córdoba, Colombia. Rev Salud Publica (Bogotá). 2009:11(3):480-9. DOI 10.1590/S0124-00642009000300016.
(24.) Stoney RJ, Esposito DH, Kozarsky P, Hamer H, Grobusch MP, Gkrania-klotsas E, et al. Infectious diseases acquired by international travellers visiting the USA. J Travel Med. 2018;25(1). DOI 10.1093/jtm/tay053.
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