Determinación de la frecuencia de variantes genéticas en los genes BRCA1 y BRCA2 y su correlación con el tipo histológico de neoplasia mamarias en caninos en Antioquia - Colombia

Authors

  • Luiggi Arango-Vásquez Universidad de Antioquia
  • Gustavo Mendoza-Fandiño Corporación Universitaria Remington

DOI:

https://doi.org/10.17533/udea.iatreia.342373
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Author Biographies

Luiggi Arango-Vásquez, Universidad de Antioquia

Estudiante de Maestría en Ciencia Básicas Biomédicas con énfasis en Genética.

Gustavo Mendoza-Fandiño, Corporación Universitaria Remington

Docente investigador grupo de investigación GINVER. Facultad de Medicina Veterinaria.

References

(1) Enginler SO, Akiş I, Toydemir TSF, Oztabak K, Haktanir D, Gündüz MC, et al. Genetic variations of BRCA1 and BRCA2 genes in dogs with mammary tumours. Vet Res Commun. 2014;38(1):21-7.

(2) Melin M, Rivera P, Arendt M, Elvers I, Murén E, Gustafson U, et al. Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours. PLoS Genet. 2016;12(5):1-20.

(3) Rivera PJ, Melin M, Biagi T, Fall T, Häggström J, Lindblad-Toh K, et al. Mammary tumor development in dogs is associated with BRCA1 and BRCA2. Cancer Res. 2009;69(22):8770-4.

(4) Borge KS, Børresen-Dale AL, Lingaas F. Identification of genetic variation in 11 candidate genes of canine mammary tumour. Vet Comp Oncol. 2011;9(4):241-50.

(5) Qiu H, Lin D. Roles of DNA mutation in the coding region and DNA methylation in the 5′ flanking region of BRCA1 in canine mammary tumors. J Vet Med Sci. 2016;78(6):943-9.

(6) Maués T, El-Jaick KB, Costa FB, Araujo GEF, Soares MVG, Moreira AS, et al. Common germline haplotypes and genotypes identified in BRCA2 exon 11 of dogs with mammary tumours and histopathological analyses. Vet Comp Oncol. 2018 Sep;16(3):379-384.

(7) Sun W, Yang X, Qiu H, Zhang D, Wang H, Huang J, et al. Relationship between three novel SNPs of BRCA1 and canine mammary tumors. J Vet Med Sci. 2015;77(11):1541-3.

(8) Hsu WL, Huang YH, Chang TJ, Wong ML, Chang SC. Single nucleotide variation in exon 11 of canine BRCA2 in healthy and cancerous mammary tissue. Vet J. 2010;184(3):351-6.

(9) Ozmen O, Kul S, Risvanli A, Ozalp G, Sabuncu A, Kul O. Somatic SNPs of the BRCA2 gene at the fragments encoding RAD51 binding sites of canine mammary tumors. Vet Comp Oncol. 2017;15(4):1479-86.

(10) Adams VJ, Evans KM, Sampson J, Wood JLN. Methods and mortality results of a health survey of purebred dogs in the UK. J Small Anim Pract. 2010;51(10):512-24.

Published

2020-07-29

How to Cite

1.
Arango-Vásquez L, Mendoza-Fandiño G. Determinación de la frecuencia de variantes genéticas en los genes BRCA1 y BRCA2 y su correlación con el tipo histológico de neoplasia mamarias en caninos en Antioquia - Colombia. Iatreia [Internet]. 2020 Jul. 29 [cited 2025 Feb. 23];33(1-S):S6-S7. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/342373

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