Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017

Authors

  • Pierina E. Marquina-Torres Universidad de San Martín de Porres, Lima, Perú
  • Juan E. Marquez-Yataco Universidad de San Martín de Porres, Lima, Perú
  • Alvaro Micael Ñaña-Cordova Universidad Científica del Sur, Lima, Perú https://orcid.org/0000-0002-1556-0954
  • Itala Jordan-Beisaga Universidad Científica del Sur, Lima, Perú
  • José F. Parodi San Martín de Porres, Lima, Perú
  • Moisés Apolaya Universidad de San Martín de Porres, Lima, Perú https://orcid.org/0000-0001-5650-9998
  • Fernando M. Runzer-Colmenares Universidad Científica del Sur, Lima, Perú https://orcid.org/0000-0003-4045-0260

DOI:

https://doi.org/10.17533/udea.iatreia.305

Keywords:

Aged, Polypharmacy, Risk factors

Abstract

Introduction: Polypharmacy, defined as the simultaneous consumption of 3 or more medications, is a significant concern in older adults, particularly in communities with limited access to healthcare services and adverse living
conditions. This study focuses on vulnerable populations in high-Andean communities of Peru.
Objectives: To determine the factors associated with polypharmacy in older adults from 12 high-Andean communities in Peru.
Methods: This observational, descriptive, and cross-sectional study included a sample of 399 elderly individuals selected through census sampling with a minimum response rate of 95%. The "Frailty in Older Adults from the Peruvian Andes" questionnaire was utilized. Multivariate analysis was conducted using Chi-square test, Student's t-test, Mann-Whitney U test, and
regression analysis for independent groups.
Results: Of the participants, 58.7% (n=234) were women, and 32.8% exhibited polypharmacy. The variables most strongly associated with polypharmacy were retirement (CI 2.07 - 8.13), previous hospitalizations (CI 0.09 - 0.31), alcohol consumption (CI 2.04 - 6.28), tobacco use (CI 2.78 - 10.12), and hypertension (CI 1.14 - 4.68).
Conclusions: Polypharmacy in older adults is influenced by sociocultural and demographic factors such as retirement, alcohol and tobacco consumption, and hypertension. Altitude did not show a significant association with polypharmacy.

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Author Biographies

Pierina E. Marquina-Torres, Universidad de San Martín de Porres, Lima, Perú

Physician and Surgeon, Faculty of Human Medicine, Universidad de San Martín de Porres, Lima, Perú.

Juan E. Marquez-Yataco, Universidad de San Martín de Porres, Lima, Perú

Physician and Surgeon, Faculty of Human Medicine, Universidad de San Martín de Porres, Lima, Perú.

Alvaro Micael Ñaña-Cordova, Universidad Científica del Sur, Lima, Perú

Head Researcher, CHANGE Research Working Group, School of Health Sciences. Human Medicine Career. Universidad Científica del Sur, Lima, Perú.

Itala Jordan-Beisaga, Universidad Científica del Sur, Lima, Perú

Head Researcher, CHANGE Research Working Group, School of Health Sciences. Human Medicine Career. Universidad Científica del Sur, Lima, Perú.

José F. Parodi , San Martín de Porres, Lima, Perú

Researcher, Center for Research on Aging (CIEN), Faculty of Human Medicine, Universidad de San Martín de Porres, Lima, Perú.

Moisés Apolaya, Universidad de San Martín de Porres, Lima, Perú

Researcher, Center for Clinical Epidemiology and Evidence-Based Medicine Research (CECLIMBE), Faculty of Human Medicine, Universidad de San Martín de Porres, Lima, Perú.

Fernando M. Runzer-Colmenares, Universidad Científica del Sur, Lima, Perú

Head Researcher, CHANGE Research Working Group, School of Health Sciences. Human Medicine Career. Universidad Científica del Sur, Lima, Perú.

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Published

2024-10-11

How to Cite

1.
Marquina-Torres PE, Marquez-Yataco JE, Ñaña-Cordova AM, Jordan-Beisaga I, Parodi JF, Apolaya M, Runzer-Colmenares FM. Factors Associated with Polypharmacy in Older Adults from 12 High-Andean Communities in Peru, 2013-2017. Iatreia [Internet]. 2024 Oct. 11 [cited 2025 Jan. 22];38(1). Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/354663

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Original research

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