Initial Approach to Patients with Dengue in the Emergency Department
DOI:
https://doi.org/10.17533/udea.iatreia.325Keywords:
Disease Management, Severe Dengue, Transmission Period, Tropical Medicine, VirusAbstract
Introduction: Dengue is defined as an acute febrile illness of viral origin transmitted by vectors and is considered of high public health interest due to its rapid expansion and impact on health systems. According to the World Health Organization (WHO), cases have increased in recent years. In Colombia, for the year 2023, the National Surveillance System (SIVIGILA) reported 131,784 cases.
Objectives: Unifying recently published information, providing clinicians with an easily accessible guide for decision-making in the emergency setting, aimed at reducing the risk of complications and mortality in patients.
Methods: Topic review with information obtained from databases such as scientific journals, websites, among others
Conclusions: It was concluded that proper patient classification based on clinical severity should be performed to determine the appropriate level of surveillance and administration of intravenous fluids, along with adequate monitoring of vital signs and paraclinical parameters. The use of anti-inflammatory drugs is contraindicated, and the transfusion of blood products increases the risk of complications.
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(1) Pan American Health Organization. Dengue: Guidelines for patient care in the Region of the Americas [Internet]. 2da Ed. Washington, D.C: PAHO; 2016. Disponible en: https://iris.paho.org/handle/10665.2/31207
(2) Baethge C, Goldbeck-Wood S, Mertens S. SANRA—a scale for the quality assessment of narrative review articles. Res Integr Peer Rev [Internet]. 2019;4(5):1-7. https://doi.org/10.1186/s41073-019-0064-8
(3) Kularatne S, Dalugama C. Dengue infection: Global importance, immunopathology and management. ClinMed [Internet]. 2022;22(1):9–13. http://dx.doi.org/10.7861/clinmed.2021-0791
(4) Souza-Salles T, Da Encarnação-Sà Guimarães T, de Alvarenga ESL, Guimarães-Ribeiro V, Ferreira-de Meneses MD, de Castro-Salles PF, et al. History, epidemiology and diagnostics of dengue in the American and Brazilian contexts: a review. Parasit Vectors [Internet]. 2018;11(1):264. https://doi.org/10.1186/s13071-018-2830-8
(5) Harapan H, Michie A, Sasmono R, Imrie A. Dengue: A Minireview. Viruses [Internet]. 2020;12(8):829. https://doi.org/10.3390/v12080829
(6) Stanaway JD, Shepard DS, Undurraga EA, Halasa YA, Coffeng LE, Brady OJ, et al. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013. Lancet Infect Dis [Internet]. 2016;16(6):712-723. https://doi.org/10.1016/s1473-3099(16)00026-8
(7) Guzman MG, Harris E. Dengue. Lancet [Internet]. 2015;385(9966):453–465. https://doi.org/10.1016/s0140-6736(14)60572-9
(8) Organización Mundial de la Salud. Dengue y dengue grave [Internet]. WHO, abril 2024. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/dengue-and-severe-dengue
(9) Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, et al. Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis [Internet]. 2012;6(8):e1760. https://doi.org/10.1371/journal.pntd.0001760
(10) Organización Mundial de la Salud. Dengue – Situación mundial [Internet]. WHO; 2023. Disponible en: https://www.who.int/es/emergencies/disease-outbreak-news/item/2023-DON498
(11) Instituto Nacional de Salud. Boletín Epidemiológico. Semana 52 [Internet]. INS; 2023. Disponible en: https://www.ins.gov.co/buscador-eventos/Paginas/Vista-Boletin-Epidemilogico.aspx
(12) Ministerio de Salud y Protección Social. Alerta epidemiológica por dengue en Colombia [Internet]. Bogotá D.C: Minsalud; 2023. Disponible en: https://www.minsalud.gov.co/Paginas/Alerta-epidemiologica-por-dengue-en-Colombia.aspx
(13) World Health Organization. Dengue guidelines, for diagnosis, treatment, prevention and control [Internet]. France: WHO; 2009. Disponible en: https://iris.who.int/bitstream/handle/10665/44188/9789241547871_eng.pdf?sequence=1
(14) Ministerio de Salud y Protección Social. Dengue Memorias [Internet]. Bogotá D.C: Minsalud; 2013. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/TH/Memorias_dengue.pdf
(15) Lee TH, Lee LK, Lye DC, Leo YS. Current management of severe dengue infection. Expert Rev Anti Infect Ther [Internet]. 2017;15(1):67-78. https://doi.org/10.1080/14787210.2017.1248405
(16) World Health Organization. Regional Office for South-East Asia. Comprehensive Guideline for Prevention and Control of Dengue and Dengue Haemorrhagic Fever. Revised and expanded edition [Internet]. WHO Regional Office for South-East; 2011. Available from: https://iris.who.int/handle/10665/204894
(17) Tsheten T, Clements ACA, Gray DJ, Adhikary RK, Furuya-Kanamori L, Wangdi K. Clinical predictors of severe dengue: a systematic review and meta-analysis. Infect Dis Poverty [Internet]. 2021;10(1):123. https://doi.org/10.1186/s40249-021-00908-2.
(18) Lee IK, Ching-Jung H, Lee CT, Liu JW. Diabetic patients suffering dengue are at risk for development of dengue shock syndrome/severe dengue: Emphasizing the impacts of co-existing comorbidity(ies) and glycemic control on dengue severity. J Microbiol Immunol Infect [Internet]. 2020;53(1):69-78. https://doi.org/10.1016/j.jmii.2017.12.005
(19) Pérez-Gutierrez N, Amador-León PA. Dengue: actualidades y estándares en el manejo clínico. Revisión de tema. Acta colomb cuid intensiv [Internet]. 2021;21(1):66–76. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0122726220300410?via%3Dihub
(20) Sirisena PDN, Mahilkar S, Sharma C, Jain J, Sunil S. Concurrent dengue infections: Epidemiology & clinical implications. Indian J Med Res [Inernet]. 2021;154(5):669-679. https://doi.org/10.4103/ijmr.ijmr_1219_18
(21) Muller DA, Depelsenaire ACI, Young PR. Clinical and Laboratory Diagnosis of Dengue Virus Infection. J Infect Dis [Internet]. 2017;215(suppl 2):S89-S95. https://doi.org/10.1093/infdis/jiw649
(22) Wong JM, Adams LE, Durbin AP, Muñoz-Jordán JL, Poehling KA, Sánchez-González LM, et al. Dengue: A Growing Problem With New Interventions. Pediatrics [Internet]. 2022;149(6):e2021055522. https://doi.org/10.1542/peds.2021-055522
(23) Panamerican Health Organization. Guidelines for the clinical diagnosis and treatment of dengue, Chikungunya, and Zika [Internet]. Washington D.C: PAHO; mayo 2024. Available from: https://www.paho.org/en/documents/guidelines-clinical-diagnosis-and-treatment-dengue-chikungunya-and-zika
(24) Organización Panamericana de la Salud. Algoritmos para el Manejo Clínico de los Casos de Dengue. Programa Regional de Enfermedades Arbovirales [Internet]. OPS; 2020. Disponible en: https://www.paho.org/sites/default/files/2020-09/2020-cde-algoritmos-manejo-clinico-dengue.pdf
(25) Frantchez V, Fornelli R, Sartori-Préez G, Arteta Z, Cabrera S, Sosa L, et al. Dengue en adultos: diagnóstico, tratamiento y abordaje de situaciones especiales. Rev Med Urug [Internet]. 2016;32(1):43–51. Disponible en: http://www.scielo.edu.uy/scielo.php?script=sci_arttext&pid=S1688-03902016000100006
(26) Araiza-Garaygordobil D, García-Martínez CE, Burgos LM, Saldarriaga C, Liblik K, Mendoza I, Martinez-Selles M. Dengue and the heart. Cardiovasc J Afr [Internet]. 2021;32(5):276-283. https://doi.org/10.5830/cvja-2021-033
(27) Mathew R, Di Santo P, Jung RG, Marbach JA, Hutson J, Simard T, et al. Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. N Engl J Med [Internet]. 2021;385(6):516-525. https://doi.org/10.1056/nejmoa2026845
(28) Lum LC, Abdel-Latif MEA, Goh AYT, Chan PWK, Lam SK. Preventive transfusion in Dengue shock syndrome-is it necessary? J Pediatr [Internet]. 2003;143(5):682-684. https://doi.org/10.1067/s0022-3476(03)00503-1
(29) Rajapakse S, de Silva NL, Weeratunga P, Rodrigo C, Fernando SR. Prophylactic and therapeutic interventions for bleeding in dengue: a systematic review. Trans R Soc Trop Med Hyg [Internet]. 2017;1;111(10):433-439. https://doi.org/10.1093/trstmh/trx079
(30) Huicho-Lozano P, Gamboa-Cruzado J, Montero-Niño J. Cuidado humanizado de personal de enfermería y satisfacción del paciente hospitalizado por dengue con signos de alarma. Bol. Malariol. y Sal. Amb. [Internet]. 2022;62(6):1279–1288. Disponible en: https://docs.bvsalud.org/biblioref/2023/05/1427587/630-1805-1-pb.pdf
(31) Guerrero-Ramírez R, La Riva-Meneses ME, De La Cruz-Ruiz M. Cuidado humanizado de enfermería según la teoría de Jean Watson, servicio de medicina del Hospital Daniel Alcides Carrión. Lima- Callao, 2015. Rev enferm Herediana [Internet]. 2016;9(2):127-136. Disponible en: https://revistas.upch.edu.pe/index.php/RENH/article/view/3017
(32) Instituto Nacional de Salud. Subdirección de Vigilancia y Control en Salud Pública. Protocolo para la vigilancia en salud pública del dengue [Internet]. Disponible en: https://www3.paho.org/col/dmdocuments/PROTOCOLO_VIGILANCIA_DENGUE.PDF
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