Mutagenic activity of human drinking water before and after chlorination in Villa Hermosa treatment plant

Authors

  • Iván Meléndez Universidad de Antioquia
  • Margarita Zuleta Universidad de Antioquia
  • Iván Marín Universidad de Antioquia
  • Jaime Calle Universidad de Antioquia
  • Diego Salazar Universidad de Antioquia

DOI:

https://doi.org/10.17533/udea.iatreia.3807

Keywords:

chlorinated wáter, genotoxic, Mutagens, Carcinogens, Pollution

Abstract

We found that pollution and chlorination have effects on mutagenicity of water from Villa Hermosa purification plant. In order to evaluate the mutagenic activity we used Ames‘ test with Salmonella strains TA-100 and TA-98. We observed that anthropogenic pollution and dental industry residues are the origin of the high indirect mutagenicity observed in water which gets into Villa Hermosa treatment plant and that before chlorination water treated in this plant (zone 5) retains about 70% of mutagens derived from pollution, Mutagens that were not retained by treatment may be added or potentiate the new mutagens formed by chlorination of drinking water (zone 6). The very high direct mutagenicity with TA-100 obtained from this chlorinated water is consistent with the type of mutagenicity of thrihalomethanes formed in chlorinated water.
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Author Biographies

Iván Meléndez, Universidad de Antioquia

Laboratorio de Mutagenesis Ambiental, Departamento de Biología, Universidad de Antioquia, Medellín, Colombia.

Margarita Zuleta, Universidad de Antioquia

Laboratorio de Mutagenesis Ambiental, Departamento de Biología, Universidad de Antioquia, Medellín, Colombia.

Iván Marín, Universidad de Antioquia

Biólogo Laboratorio de Mutagenesis Ambiental, Departamento de Biología, Universidad de Antioquia, Medellín, Colombia.

Jaime Calle, Universidad de Antioquia

Laboratorio de Mutagenesis Ambiental, Departamento de Biología, Universidad de Antioquia, Medellín, Colombia.

Diego Salazar, Universidad de Antioquia

Biólogo Laboratorio de Mutagenesis Ambiental, Departamento de Biología, Universidad de Antioquia, Medellín, Colombia.

Published

2001-03-17

How to Cite

1.
Meléndez I, Zuleta M, Marín I, Calle J, Salazar D. Mutagenic activity of human drinking water before and after chlorination in Villa Hermosa treatment plant. Iatreia [Internet]. 2001 Mar. 17 [cited 2025 Jan. 22];14(3):pág. 167-175. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/3807

Issue

Section

Original research

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