Linfoma anaplásico de células gigantes asociado a implantes mamarios, una enfermedad desconocida

Autores/as

DOI:

https://doi.org/10.17533/udea.iatreia.193

Palabras clave:

Contractura Capsular en Implantes, Diagnóstico por Imagen, Implantes de Mama, Linfoma Anaplásico de células grandes, Tomografía Computarizada de Emisión, Ultrasonografía

Resumen

Existe un gran número de enfermedades del tejido mamario que tienen patrones radiológicos específicos y hallazgos imagenológicos concretos. No obstante, el linfoma anaplásico de células gigantes asociado a implantes mamarios (LACG-AIM) es una enfermedad con hallazgos poco específicos que ha presentado un aumento en su incidencia debido al crecimiento exponencial de la mamoplastia de aumento a lo largo de los años en todo el mundo, así como al uso de implantes tanto en cirugía estética como reconstructiva. En este artículo se realiza una revisión de la epidemiología, etiología, fisiopatología y diagnóstico del LACG-AIM. Se plantean hallazgos radiológicos sugestivos de esta enfermedad, lo que permite al radiólogo aportar información al equipo tratante para el diagnóstico y la planificación quirúrgica en caso de ser necesario.

|Resumen
= 472 veces | PDF
= 175 veces| | HTML
= 0 veces|

Descargas

Los datos de descargas todavía no están disponibles.

Biografía del autor/a

Marco Paipilla-Sandoval, Universidad El Bosque, Bogotá, Colombia

Médico cirujano, Universidad El Bosque, Bogotá, Colombia.

Juliana Gutierrez-Sarmiento, Universidad Militar Nueva granada, Bogotá, Colombia

Médico general, Universidad Militar Nueva granada, Bogotá, Colombia.

Dayanna Pinto-Martinez, Universidad El Bosque, Bogotá, Colombia

Médico cirujano, Universidad El Bosque, Bogotá, Colombia.

Herley Aguirre-Serrano, Universidad Nacional de Colombia, Bogotá, Colombia

Cirujano plástico estético y reconstructivo, Universidad Nacional de Colombia, Bogotá, Colombia.

Larry Javier Robles , Universidad El Bosque, Bogotá, Colombia

Médico cirujano, Universidad El Bosque, Bogotá, Colombia.

Citas

(1) Alotaibi S, Hamadani M, Al-Mansour M, Aljurf M. Breast Implant-associated Anaplastic Large Cell Lymphoma. Clin Lymphoma Myeloma Leuk [Internet]. 2021 [Consultado 2022 Feb 17];12(3):e272-76. DOI 10.1016/j.clml.2020.12.005.

(2) Ali N, Sindhu K, Bakst RL. A Rare Case of a Transgender Female With Breast Implant-Associated Anaplastic Large Cell Lymphoma Treated With Radiotherapy and a Review of the Literature. J Investig Med high impact case reports [Internet]. 2019 [cited 2022 Feb 18];7:2324709619842192. DOI 10.1177/2324709619842192.

(3) Patrick N, Meerkotter D. Breast implant-associated anaplastic large cell lymphoma. Repr from AJGP [Internet]. 2021 [cited 2022 Feb 16];50(4). DOI 10.31128/AJGP-04-20-5360.

(4) Akdeniz-Dogan Z, Miranda RN, Iyer S, Steiner RE, Singh P, Clemens MW. Anaplastic Large Cell Lymphoma of the Breast Arising in a Burn Cicatrix. Aesthet Surg J [Internet]. 2020 Mar [cited 2022 Feb 16];40(4):NP159–63. DOI 10.1093/asj/sjz245.

(5) Lyapichev KA, Piña-Oviedo S, Jeffrey Medeiros L, Evans MG, Liu H, Miranda AR, et al. A proposal for pathologic processing of breast implant capsules in patients with suspected breast implant anaplastic large cell lymphoma HHS Public Access. Mod Pathol [Internet]. 2020 [Consultado 2022 Feb 17];33(3):367–79. DOI 10.1038/s41379-019-0337-2.

(6) Nelson JA, Dabic S, Mehrara BJ, Cordeiro PG, Disa JJ, Pusic AL, et al. Breast Implant-Associated Anaplastic Large Cell Lymphoma Incidence: Determining an Accurate Risk. Ann Surg [Internet]. 2020;272(3):403–9. DOI 10.1097/SLA.0000000000004179.

(7) FDA. Medical Device Reports of Breast Implant-Associated Anaplastic Large Cell Lymphoma [Internet]. 2020. Disponible en: https://www.fda.gov/medical-devices/breast-implants/medical-device-reports-breast-implant-associated-anaplastic-large-cell-lymphoma

(8) FDA. FDA Updates Analysis of Medical Device Reports of Breast Implant Illness and Breast Implant-Associated Lymphoma [Internet]. 2020 [Consultado 2021 Aug 20]. Disponible en: https://www.fda.gov/news-events/press-announcements/fda-updates-analysis-medical-device-reports-breast-implant-illness-and-breast-implant-associated

(9) Pelc Z, Skórzewska M, Kurylcio A, Olko P, Dryka J, Machowiec P, et al. Current Challenges in Breast Implantation. Medicina (Kaunas) [Internet]. 2021 Nov [Consultado 2022 Feb 16];57(11):1214. DOI 10.3390/medicina57111214.

(10) Manahan MA. What Do Clinicians and Organizations Owe Patients With Recalled Implanted Devices or Materials? AMA J ethics [Internet]. 2021 [Consultado 2022 Feb 16];23(9):E679-684. DOI 10.1001/amajethics.2021.679.

(11) Marra A, Viale G, Pileri SA, Pravettoni G, Viale G, De Lorenzi F, et al. Breast implant-associated anaplastic large cell lymphoma: A comprehensive review. Cancer Treat Rev [Internet]. 2020 Mar [cited 2022 Mar 1];84:101963. DOI 10.1016/j.ctrv.2020.101963.

(12) Turton P, El-Sharkawi D, Lyburn I, Sharma B, Mahalingam P, Turner SD, et al. UK Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma on behalf of the Medicines and Healthcare products Regulatory Agency Plastic, Reconstructive and Aesthetic Surgery Expert Advisory Group. Br J Haematol [Internet]. 2021 Feb [Consultado 2022 Mar 1];192(3):444–58. DOI 10.1111/bjh.17194.

(13) Ben-Nun O, Bitterman N, Tadmor T, Bejar J, Shalata A, Yarin H, et al. Anaplastic Large T-Cell Lymphoma Associated with Breast Implants – Rare Disease. Isr Med Assoc J [Internet]. 2017 [cited 2022 Mar 1];19:390–2. Disponible en: https://www.ima.org.il/FilesUploadPublic/IMAJ/0/239/119512.pdf

(14) Ossa-Gomez CA, Robledo-Abad JF, Duque A, Huertas R, Fidalgo AM, Rivas-Taffur G, et al. Breast Implant-associated Anaplastic Large Cell Lymphoma in Colombia: Report of a Multidisciplinary National Registry. Plast Reconstr Surg - Glob Open [Internet]. 2020;8(8):e3013- DOI 10.1097/GOX.0000000000003013.

(15) Turner SD. The Cellular Origins of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Implications for Immunogenesis. Aesthetic Surg J [Internet]. 2019;39(Suppl_1):S21–7. DOI 10.1093/asj/sjy229.

(16) Srinivasa DR, Miranda RN, Kaura A, Francis AM, Campanale A, Boldrini R, et al. Global Adverse Event Reports of Breast Implant-Associated ALCL: An International Review of 40 Government Authority Databases. Plast Reconstr Surg [Internet]. 2017 May [Consultado 2022 Feb 18];139(5):1029–39. DOI 10.1097/PRS.0000000000003233.

(17) Evren S, Khoury T, Neppalli V, Cappuccino H, Hernandez-Ilizaliturri FJ, Kumar P. Breast Implant-Associated Anaplastic Large Cell Lymphoma (ALCL): A Case Report. Am J Case Rep [Internet]. 2017 [Consultado 2022 Feb 18];18:605–10. DOI 10.12659/AJCR.903161.

(18) Clemens MW, Nava MB, Rocco N, Miranda RN. Understanding rare adverse sequelae of breast implants: Anaplastic large-cell lymphoma, late seromas, and double capsules. Gland Surg [Internet]. 2017;6(2):169–84. DOI 10.21037/gs.2016.11.03.

(19) Choi KJ, Brown AM, Pham CH, Patel SV, Patel KM, Carey J. Current Considerations of Breast Implant–Associated Anaplastic Large Cell Lymphoma in Breast Surgery: a Systematic Review. Curr Breast Cancer Rep [Internet]. 2019;11(4):373–80. DOI 10.1007/s12609-019-00342-2.

(20) Johnson L, O’Donoghue JM, McLean N, Turton P, Khan AA, Turner SD, et al. Breast implant associated anaplastic large cell lymphoma: The UK experience. Recommendations on its management and implications for informed consent. Eur J Surg Oncol [Internet]. 2017 Aug [Consultado 2022 Feb 18];43(8):1393–401. DOI 10.1016/j.ejso.2017.05.004.

(21) Lee JH. Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL). Yeungnam Univ J Med [Internet]. 2021 Jul [Consultado 2022 Feb 19];38(3):175–82. DOI 10.12701/yujm.2020.00801.

(22) De-Boer M, Van-Leeuwen FE, Hauptmann M, Overbeek LIH, De Boer JP, Hijmering NJ, et al. Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast. JAMA Oncol [Internet]. 2018 Mar [Consultado 2022 Feb 18];4(3):335-341. DOI 10.1001/jamaoncol.2017.4510.

(23) Di-Napoli A, De-Cecco L, Piccaluga PP, Navari M, Cancila V, Cippitelli C, et al. Transcriptional analysis distinguishes breast implant-associated anaplastic large cell lymphoma from other peripheral T-cell lymphomas. Mod Pathol [Internet]. 2019 [Consultado 2022 Feb 18];32( 2):216–30. DOI 10.1038/s41379-018-0130-7.

(24) Di-Napoli A, Jain P, Duranti E, Margolskee E, Arancio W, Facchetti F, et al. Targeted next generation sequencing of breast implant-associated anaplastic large cell lymphoma reveals mutations in JAK/STAT signalling pathway genes, TP53 and DNMT3A. Br J Haematol [Internet]. 2018 Mar [Consultado 2022 Feb 18];180(5):741–4. DOI 10.1111/bjh.14431.

(25) Oishi N, Brody GS, Ketterling RP, Viswanatha DS, He R, Dasari S, et al. Genetic subtyping of breast implant–associated anaplastic large cell lymphoma. Blood [Internet]. 2018 Aug [Consultado 2022 Feb 18];132(5):544-47. DOI 10.1182/blood-2017-12-821868.

(26) Kang SH, Sutthiwanjampa C, Heo CY, Kim WS, Lee SH, Park H. Current Approaches Including Novel Nano/Microtechniques to Reduce Silicone Implant-Induced Contracture with Adverse Immune Responses. Int J Mol Sci [Internet]. 2018 Apr [Consultado 2022 Feb 18];19(4):1171. DOI 10.3390/ijms19041171.

(27) Rastogi P, Deva AK, Prince HM. Breast Implant-Associated Anaplastic Large Cell Lymphoma. Curr Hematol Malig Rep [Internet]. 2018;13(6):516–24. DOI 10.1007/s11899-018-0478-2.

(28) Deva AK, Turner SD, Kadin ME, Magnusson MR, Prince HM, Miranda RN, et al. Etiology of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): Current Directions in Research. Cancers (Basel) [Internet]. 2020 Dec [Consultado 2022 Feb 19];12(12):1–14. DOI 10.3390/cancers12123861.

(29) Jaffe ES, Ashar BS, Clemens MW, Feldman AL, Gaulard P, Miranda RN, et al. Best practices guideline for the pathologic diagnosis of breast implant–associated anaplastic large-cell lymphoma. J Clin Oncol [Internet]. 2020;38(10):1102–11. DOI 10.1200/JCO.19.02778.

(30) Clemens MW, Jacobsen ED, Horwitz SM. 2019 NCCN Consensus Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL). Aesthet Surg J [Internet]. 2019;39(Suppl 1):S3–13. DOI 10.1093/asj/sjy331.

(31) Fitzal F, Turner SD, Kenner L. Is breast implant-associated anaplastic large cell lymphoma a hazard of breast implant surgery? Open Biol [Internet]. 2019;9(4):190006. DOI 10.1098/rsob.190006.

(32) Misad C, Walker K, Valbuena JR, Guerra C, Camus M, Ocqueteau M, et al. Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico. Rev Med Chile [Internet]. 2020;148(8):1207–12.DOI 10.4067/S0034-98872020000801207.

(33) Mehta-Shah N, Clemens MW, Horwitz SM. How I treat breast implant–associated anaplastic large cell lymphoma. Blood [Internet]. 2018 Nov [Consultado 2022 Feb 18];132(18):1889. DOI 10.1182/blood-2018-03-785972.

(34) Walker JN, Hanson BM, Pinkner CL, Simar SR, Pinkner JS, Parikh R, et al. Insights into the Microbiome of Breast Implants and periprosthetic tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma. Scientific Reports [Internet] [Consultado 2022 Feb 17];9:10393. DOI 10.1038/s41598-019-46535-8.

(35) Ducastel N, Cimpean IM, Theate I, Vanhooteghem O. Breast erythema and nodular skin metastasis as the first manifestation of breast implant-associated anaplastic large cell lymphoma. Rare Tumors [Internet]. 2021 [Consultado 2022 Feb 19];13. DOI 10.1177/20363613211028498.

(36) Kalyon H, Öztürk E, Tuzlalı S, Akay OM, Ferhanoğlu B. Breast Implant-Associated Anaplastic Large-Cell Lymphoma: A Case Report. Turk J Haematol [Internet]. 2019 [Consultado 2022 Feb 17];36(4):296–9. DOI 10.4274/tjh.galenos.2019.2019.0162.

(37) Ferrufino-Schmidt MC, Medeiros LJ, Liu H, Clemens MW, Hunt KK, Laurent C, et al. Clinicopathologic Features and Prognostic Impact of Lymph Node Involvement in Patients With Breast Implant-associated Anaplastic Large Cell Lymphoma HHS Public Access. Am J Surg Pathol [Internet]. 2018;42(3):293–305. DOI 10.1097/PAS.0000000000000985.

(38) Sutton EJ, Dashevsky BZ, Watson EJ, Tyagi N, Bernard-Davila B, Martinez D, et al. Incidence of benign and malignant peri-implant fluid collections and masses on magnetic resonance imaging in women with silicone implants. Cancer Med [Internet]. 2020;9:3261–7. DOI 10.1002/cam4.2189.

(39) Bitterman N, Simoviz P, Tadmor T, Tzur L, Calderon N, Ben-Nun O. Fat Grafting after Implant Removal Due to Anaplastic Large Cell Lymphoma May Mimic Recurrence. Isr Med Assoc J [Internet]. 2019 [Consultado 2022 Feb 16];21:520–2. Disponible en: https://www.ima.org.il/FilesUploadPublic/IMAJ/0/378/189302.pdf

(40) Kim IK, Hong KY, Lee CK, Choi BG, Shin H, Lee JH, et al. Breast Surgery Analysis of the Molecular Signature of Breast Implant-Associated Anaplastic Large Cell Lymphoma in an Asian Patient. Aesthet Surg J [Internet]. 2020 [Consultado 2022 Feb 17];41(5):NP214-NP222. DOI 10.1093/asj/sjaa398.

(41) McCarthy CM, Loyo-Berríos N, Qureshi AA, Mullen E, Gordillo G, Pusic AL, et al. Patient Registry and Outcomes for Breast Implants and Anaplastic Large Cell Lymphoma Etiology and Epidemiology (PROFILE): Initial Report of Findings 2012-2018. Plast Reconstr Surg [Internet]. 2019 Mar;143(3S):65S-73S. DOI 10.1097/PRS.000000000000557.

(42) Rajabiani A, Arab H, Emami A, Manafi A, Bazzaz N, Saffar H. Anaplastic Large Cell Lymphoma Associated with Breast Implant: A Case Report. World J Plast Surg [Internet]. 2012;1(1):46-50. PMC4344966.

(43) DePaola NEK, Coggins H. Breast Implant-Associated Anaplastic Large Cell Lymphoma: What We Know. J Adv Pract Oncol [Internet]. 2019;10(1):54–61. PMC6605706.

(44) Ben-Naftali Y, Barnea Y, Clemens MW, Bar-Meir E. How Common Is Breast Implant-Associated Anaplastic Large Cell Lymphoma? First Four Cases in Israel. Isr Med Assoc J [Internet]. 2019 Aug [Consultado 2022 Feb 17];21(8):512–5. Available from: https://www.ima.org.il/FilesUploadPublic/IMAJ/0/378/189287.pdf

(45) Siminiak N, Czepczyński R. PET-CT for the staging of breast implant-associated anaplastic large cell lymphoma. Nucl Med Rev [Internet]. 2019 Jul [Consultado 2022 Feb 16];22(2):90–1. DOI 10.5603/NMR.a2019.0015.

(46) Martínez-Ramos D, Simón-Monterde L, Suelves-Piqueres C, Queralt-Martí R, Laguna-Sastre M. Anaplastic large cell lymphoma associated with breast implants. Importance for the surgeon Linfoma anaplásico de células grandes asociado a implantes mamarios. Importancia para el cirujano. Cir Cir [Internet]. 2018 [Consultado 2022 Feb 17];86(5):459–64. DOI 10.24875/CIRU.18000314.

(47) Adrada BE, Miranda RN, Rauch GM, Arribas E, Kanagal-Shamanna R, Clemens MW, et al. Breast implant-associated anaplastic large cell lymphoma: Sensitivity, specificity, and findings of imaging studies in 44 patients. Breast Cancer Res Treat [Internet]. 2014;147(1):1–14. DOI 10.1007/s10549-014-3034-3.

(48) St Cyr TL, Pockaj BA, Northfelt DW, Craig FE, Clemens MW, Mahabir RC. Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Current Understanding and Recommendations for Management. Plast Surg (Oakv) [Internet]. 2020 May;28(2):117–26. DOI 10.1177/2292550320925906.

(49) Coombs DM, Grover R, Prassinos A, Gurunluoglu R. Breast augmentation surgery: Clinical considerations. Cleve Clin J Med [Internet]. 2019 Feb [Consultado 2022 Feb 18];86(2):111–22. DOI 10.3949/ccjm.86a.18017.

(50) de Oliveira-Sermoud LMC, Romano S, Chveid M, da Silva Amorim GL. Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Why Must We Learn About It? J Glob Oncol [Internet]. 2019 [Consultado 2022 Feb 17]; DOI 10.1200/JGO.19.00224.

Descargas

Publicado

23-09-2022

Cómo citar

1.
Paipilla-Sandoval M, Gutierrez-Sarmiento J, Pinto-Martinez D, Aguirre-Serrano H, Robles LJ. Linfoma anaplásico de células gigantes asociado a implantes mamarios, una enfermedad desconocida. Iatreia [Internet]. 23 de septiembre de 2022 [citado 22 de enero de 2025];36(2). Disponible en: https://revistas.udea.edu.co/index.php/iatreia/article/view/348886

Número

Sección

Artículos de revisión