Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population

Authors

  • Jennyfer FLÓREZ-MENDEZ University of Santiago of Chile (USACH) https://orcid.org/0000-0003-1515-6262
  • Jorge Yezid FLÓREZ University of Pamplona
  • Elevina PÉREZ Central Venezuela University
  • Mary LARES Central Venezuela University

DOI:

https://doi.org/10.17533/udea.vitae.v26n1a02

Keywords:

Antioxidant, cocoa, chocolate, flavonoids, resveratrol.

Abstract

Background: Chocolate is a product with high nutritional value, of sensory characteristics accepted and preferred by the consumer, in addition to beneficial to health. Based on the benefits attributed to cocoa components, investigations have shown that chocolate consumption has been involved in the modulation of blood pressure protection, the lipid profile, the activation of platelets, and insulin sensitivity. Objective: Evaluate the effect of consuming a tablet of chocolate enriched with tryptophan present in the peanut and resveratrol contained in the peel flour and grape seed, on biochemical markers and oxidative stress in a healthy population. Methods: The study was conducted in 10 subjects aged between 20 and 40 years, who consumed daily for 21 days, a chocolate bar of 15 g enriched with tryptophan and resveratrol. Before starting the study and after 21 days, the participants were given weighty measures, waist, hip and blood pressure. As well as blood samples, where was analyzed: glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL, uric acid, insulin and markers of oxidative stress 8- isoprostane and catalase. The non-parametric statistical tests were applied Kruskal-Wallis for n=10, with a value of significance of 0.05. Results: A statistically significant decrease in insulin values and oxidative stress marker 8-isoprostane was stopped, whereas catalase values increased significantly. Conclusions: The consumption of chocolate enriched with tryptophan and resveratrol, does not alter the biochemical parameters of glycemia, creatinine, triglycerides, total cholesterol, HDL, LDL, VLDL and uric acid. But it significantly helps the decrease of insulin in blood and could have beneficial health effects related to the reduction of oxidative stress, after consuming 15 g of the chocolate during 21 days.

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Author Biographies

Jennyfer FLÓREZ-MENDEZ, University of Santiago of Chile (USACH)

Doctor degree in Food Science and Technology. CEUS Llanquihue Studies Center

Jorge Yezid FLÓREZ, University of Pamplona

Magister Scientiarum in Higher Education. Healthy Faculty. Physical Education Department

Elevina PÉREZ, Central Venezuela University

Doctor degree in Food Science and Technology. Titular professor. Faculty of Science. Institute of Science and Technology of Food

Mary LARES, Central Venezuela University

Doctor degree in Food Science and Technology. Titular professor. Faculty of Science. Institute of Science and Technology of Food. School of Nutrition and Dietetics, Faculty of Medicine, Research Laboratory of Endocrinology of Military Hospital "Dr. Carlos Arvelo".

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Published

30-04-2019

How to Cite

FLÓREZ-MENDEZ, J., FLÓREZ, J. Y., PÉREZ, E., & LARES, M. (2019). Effect of the consumption of chocolate enriched with tryptophan and resveratrol on biochemical markers and oxidative stress in a healthy population. Vitae, 26(1), 8–16. https://doi.org/10.17533/udea.vitae.v26n1a02

Issue

Section

Pharmacology and Toxicology