Índice estadístico para el diagnóstico de la sarcopenia en mujeres mayores de 60 años físicamente activas: Un estudio transversal
DOI:
https://doi.org/10.17533/udea.rfnsp.e355147Keywords:
Dynapenia, explosive strength, handgrip strength, body compositionAbstract
Objective: The detection and classification of sarcopenia involves the analysis of many variables (50 to 60), which increases the time and costs required to diagnose and manage this condition. The objective of the study was to develop a synthetic statistical index to diagnose and classify sarcopenia in physically active women over 60 years old.
Methodology: We conducted a cross-sectional study on 100 physically active women (64.88 ±4.4 years) on whom body composition measurements, muscle strength, and gait tests were performed. One thousand random selections of both training and test sets (80% and 20%, respectively) were made, logistic regression was fitted, and the regularization procedure (Elastic net regression) was performed.
Results: the skeletal appendicular mass index (kg/m2), muscle mass (kg/m2) and SAMI (kg/m2) are highly correlated (0.93) and slow gait speed (m/sec) were the variables that contributed the most to the diagnosis of sarcopenia with a visibly high correlation, (94%).
Conclusion: appendicular lean mass, gait speed, and explosive strength sufficiently describe the state of muscle and functional deterioration (sarcopenia) in physically active older women. Also, the precise identification and classification of this condition facilitates comprehensive multidisciplinary intervention, increasing the positive impact of health promotion and disease prevention programs.
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1 Shafiee G, Keshtkar A, Soltani A, Ahadi Z, Larijani B, Heshmat R. Prevalence of sarcopenia in the world: A systematic review and meta-analysis of general population studies. J Diabetes Metab Disord. 2017;16:21. doi:10.1186/s40200-017-0302-x
2 Rojas-Bermúdez C, Buckcanan-Vargas A, Benavides-Jiménez G. Sarcopenia: Abordaje integral del adulto mayor. Rev Med Sinergia. 2019;4(5):24 - 34. doi:10.31434/rms.v4i5.194
3 Rodríguez-Rejón AI, Ruiz-López MD, Artacho R. Diagnóstico y prevalencia de sarcopenia en residencias de mayores: EWGSOP2 frente al EWGSOP1. Nutr Hosp. 2019;36:1074-1080. doi:10.20960/nh.02573
4 Verjans-Janssen SRB, Van Kann DHH, Gerards S, Vos SB, Jansen MWJ, Kremers SPJ. Study protocol of the quasi-experimental evaluation of “KEIGAAF”: A context-based physical activity and nutrition intervention for primary school children. BMC Public Health. 2018;18(1):842. doi:10.1186/s12889-018-5764-3
5 Burgos-Peláez R. Sarcopenia en ancianos. Endocrinol y Nutr. 2006;53(5):335-344. doi:10.1016/S1575-0922(06)71113-5
6 Gutiérrez-Cortés WA, Martínez-Fernández FE, Olaya-Sanmiguel LC. Sarcopenia, una patología nueva que impacta a la vejez. Rev Colomb Endocrinol Diabetes Metab. 2018;5(1):28-36. doi:10.53853/encr.5.1.339
7 Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T et al. Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing. 2019;48:16-31. doi:10.1093/ageing/afy169
8 Mayhew AJ, Amog K, Phillips S, Parise G, McNicholas PD, de Souza RJ et al. The prevalence of sarcopenia in community-dwelling older adults, an exploration of differences between studies and within definitions: A systematic review and meta-analyses. Age Ageing. 2019;48(1):48-56. doi:10.1093/ageing/afy106
9 Kołodziej M, Ignasiak Z, Ignasiak T. Annual changes in appendicular skeletal muscle mass and quality in adults over 50 y of age, assessed using bioelectrical impedance analysis. Nutrition. 2021;90:111342. doi:10.1016/j.nut.2021.111342
10 Lee PH, Macfarlane DJ, Lam TH, Stewart SM. Validity of the International Physical Activity Questionnaire Short Form (IPAQ-SF): A systematic review. Int J Behav Nutr Phys Act. 2011;8:115. doi:10.1186/1479-5868-8-115
11 Jenicek M. Foundations of evidence-based medicine: Clinical epidemiology and beyond: CRC Press2019.
12 Janssen I, Baumgartner RN, Ross R, Rosenberg IH, Roubenoff R. Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol. 2004;159(4):413-421. doi:10.1093/aje/kwh058
13 Fernandes S, Rodrigues da Silva E, New York B, Macedo P, Gonçalves R, Camara S et al. Cutoff points for grip strength in screening for sarcopenia in community-dwelling older-adults: A systematic review. J Nutr Health Aging. 2022;26(5):452-460. doi:10.1007/s12603-022-1788-6
14 Gledhill N, Shephard RJ, Jamnik V, Bredin SSD, Warburton DER. Consensus on evidence-based preparticipation screening and risk stratification. Annu Rev Gerontol Geriatr. 2016;36(1):53-102. doi:10.1891/0198-8794.36.53
15 Heyward V. Evaluación y prescripción del ejercicio: Paidotribo, Barcelona, 2006.
16 Fan Y, Zhang B, Huang G, Zhang G, Ding Z, Li Z et al. Sarcopenia: Body composition and gait analysis. Front Aging Neurosci. 2022;14:909551. doi:10.3389/fnagi.2022.909551
17 Ditroilo M, Forte R, McKeown D, Boreham C, De Vito G. Intra- and inter-session reliability of vertical jump performance in healthy middle-aged and older men and women. J Sports Sci. 2011;29(15):1675-1682. doi:10.1080/02640414.2011.614270
18 Bohannon RW, Schaubert KL. Test-retest reliability of grip-strength measures obtained over a 12-week interval from community-dwelling elders. J Hand Ther. 2005;18(4):426-427, quiz 428. doi:10.1197/j.jht.2005.07.003
19 Ostir GV, Berges IM, Ottenbacher KJ, Fisher SR, Barr E, Hebel JR et al. Gait speed and dismobility in older adults. Arch Phys Med Rehabil. 2015;96(9):1641-1645. doi:10.1016/j.apmr.2015.05.017
20 van Buuren S, Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R. J Stat Softw. 2011;45(3):1 - 67. doi:10.18637/jss.v045.i03
21 Zou H, Hastie T. Regularization and variable selection via the elastic net. J R Statist Soc B 2005;67(2):301-320. doi:10.1111/j.1467-9868.2005.00503.x
22 World Medical Association. Declaration of Helsinki: Medical research involving human subjects. JAMA. 2013;310(20):2191-2194. doi:10.1001/jama.2013.281053
23 Boehmke FJ, Brockway M, Desmarais BA, Harden JJ, LaCombe S, Linder F et al. SPID: A new database for inferring public policy innovativeness and diffusion networks. Policy Stud J. 2020;48(2):517-545. doi:10.1111/psj.12357
24 Pennington N, Hastie R. Explaining the evidence: Tests of the Story Model for juror decision making. J Pers Soc Psychol. 1992;62(2):189–206. doi:10.1037/0022-3514.62.2.189
25 Shepherd JA, Ng BK, Sommer MJ, Heymsfield SB. Body composition by DXA. Bone. 2017;104:101-105. doi:10.1016/j.bone.2017.06.010
26 Goodpaster BH, Park SW, Harris TB, Kritchevsky SB, Nevitt M, Schwartz AV et al. The loss of skeletal muscle strength, mass, and quality in older adults: The health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2006;61(10):1059-1064. doi:10.1093/gerona/61.10.1059
27 Barbat-Artigas S, Plouffe S, Pion CH, Aubertin-Leheudre M. Toward a sex-specific relationship between muscle strength and appendicular lean body mass index? J Cachexia Sarcopenia Muscle. 2013;4(2):137-144. doi:10.1007/s13539-012-0100-8
28 Gianoudis J, Bailey CA, Daly RM. Associations between sedentary behaviour and body composition, muscle function and sarcopenia in community-dwelling older adults. Osteoporos Int. 2015;26(2):571-579. doi:10.1007/s00198-014-2895-y
29 Lee Y, Shin S. The effect of body composition on gait variability varies with age: Interaction by hierarchical moderated regression analysis. Int J Environ Res Public Health. 2022;19(3). doi:10.3390/ijerph19031171
30 Daly RM, Rosengren BE, Alwis G, Ahlborg HG, Sernbo I, Karlsson MK. Gender specific age-related changes in bone density, muscle strength and functional performance in the elderly: a-10 year prospective population-based study. BMC Geriatr. 2013;13(1):71. doi:10.1186/1471-2318-13-71
31 Larsson L, Degens H, Li M, Salviati L, Lee Yi, Thompson W et al. Sarcopenia: Aging-related loss of muscle mass and function. Physiol Rev. 2018;99(1):427-511. doi:10.1152/physrev.00061.2017
32 Drummond FMM, Lourenço RA, Lopes CS. Association between fear of falling and spatial and temporal parameters of gait in older adults: The FIBRA-RJ study. Eur Geriatr Med. 2022;13(2):407-413. doi:10.1007/s41999-021-00601-5
33 Sofi F, Capalbo A, Pucci N, Giuliattini J, Condino F, Alessandri F et al. Cardiovascular evaluation, including resting and exercise electrocardiography, before participation in competitive sports: cross sectional study. BMJ. 2008;337:a346. doi:10.1136/bmj.a346
34 Lin Y-C, Tseng I-J, Lu Y-C, Yang S-W, Wu C-C, Lin Y-N et al. Muscle mass and gait characteristics in older women fallers vs. non-fallers. J Clin Med. 2021;10(17). doi:10.3390/jcm10173924
35 Alcazar J, Alegre LM, Van Roie E, Magalhães JP, Nielsen BR, González-Gross M et al. Relative sit-to-stand power: aging trajectories, functionally relevant cut-off points, and normative data in a large European cohort. J Cachexia Sarcopenia Muscle. 2021;12(4):921-932. doi:10.1002/jcsm.12737
36 Rubenstein LZ. Falls in older people: epidemiology, risk factors and strategies for prevention. Age Ageing. 2006;35(suppl 2):ii37-ii41. doi:10.1093/ageing/afl084
37 Miller RM, Freitas EDS, Heishman AD, Peak KM, Buchanan SR, Kellawan JM et al. Muscle performance changes with age in active women. Int J Environ Res Public Health. 2021;18(9). doi:10.3390/ijerph18094477
38 Ramírez-Villada J, Arango-Paternina C, Tibaduiza-Romero A, Rodríguez-Perdomo L, Molina-Restrepo N, Márquez-Arabia J. Functional autonomy and sarcopenia markers in women over 55 years of age. Rev Fac Med. 2021;69(4):e84849. doi:10.15446/revfacmed.v69n4.84849
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