Seroincidencia de anticuerpos IgG del SARS-CoV-2 y factores de riesgo en trabajadores sanitarios asintomáticos del Hospital Departamental de Villavicencio

Lida Carolina Lesmes Rodriguez; Didier José Velandia-Bobadilla; Dumar Alexander Jaramillo-Hernández

doi:10.17533/udea.rfnsp.e346034

Autores

Lida Carolina Lesmes Rodriguez Universidad de los Llanos https://orcid.org/0000-0002-1312-0891
Didier José Velandia-Bobadilla Universidad de los Llanos https://orcid.org/0000-0002-5568-3326
Dumar Alexander Jaramillo-Hernández Universidad de los Llanos https://orcid.org/0000-0003-1377-1747

DOI:

https://doi.org/10.17533/udea.rfnsp.e346034

Palavras-chave:

Palavras chave: doença do Coronavírus 2019 (COVID-19), imunoglobulina classe G (IgG), pandemia, Coronavírus 2 causador da síndrome respiratória aguda grave (SARS-CoV-2), ELISA indireto.

Resumo

Objetivo: Estimar a incidência zero acumulada de imunoglobulinas (Ig) classe G (IgG) anti-SARS-CoV-2 em profissionais de saúde assintomáticos e sua associação epidemiológica dentro das áreas funcionais do Hospital Estadual de Villavicencio (HDV).

Metodologia: Foi realizado um estudo observacional analítico longitudinal de uma coorte de profissionais, no qual a cada 21 dias, em três ocasiões mediram-se IgG anti-SARS-CoV-2 em soro sanguíneo, através de ELISA indireto, em uma amostra representativa aleatória (n = 105) de profissionais de saúde do hospital (N =756). Como instrumento de recolecção de dados foi usada uma pesquisa, onde cada profissional de saúde declarou não ter sido diagnosticado com COVID-19, e igualmente registrou a informação sobre as variáveis independentes: sexo, idade, condições de trabalho, área de atuação e comorbidades.

Resultados: A prevalência inicial para SARS-CoV-2 entre os profissionais de saúde assintomáticos do HDV foi de 9,52% (IC 95% 5,25-16,65). A incidência zero acumulada durante 42 dias foi de 12,38% (IC 95% 7,38-20,04). O risco relativo (RR) foi utilizado para estabelecer os fatores de risco associados às variáveis independentes. O sexo masculino (RR ajustado 3,34, IC 95% 1,98-5,86), obesidade (RR ajustado 10,98, IC 95% 1,41-85,98) e sexo feminino (RR ajustado 2,15, IC 95% 1,12-4,31) nas áreas funcionais de Internação, Unidade de Terapia Intensiva e Urgências, respectivamente, são fatores de risco no HDV.

Conclusão: Um total de 13 de 105 profissionais de saúde do hospital foram detectados positivamente para SARS-CoV-2 e foram assintomáticos durante 42 dias de seguimento epidemiológico. Além disso, existem importantes fatores de risco na sua exposição a este vírus no HDV.

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