Insuficiencia renal aguda inducida por rabdomiolisis

  • John Fredy Nieto-Ríos Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín.
  • Juliana Vega-Miranda Hospital Pablo Tobón Uribe, Medellín.
  • Lina María Serna-Higuita Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín.
Palabras clave: Insuficiencia Renal Aguda, Mioglobina, Músculo Esquelético, Necrosis, Rabdomiolisis

Resumen

La insuficiencia renal aguda (IRA) es una causa frecuente de morbilidad y mortalidad en los servicios de urgencias, hospitalización y cuidado crítico, siendo la rabdomiolisis responsable del 15 % de los casos en los centros hospitalarios de alta complejidad. La rabdomiolisis consiste en daño muscular con necrosis y liberación a la circulación de componentes intracelulares, y puede tener múltiples causas. El daño renal por rabdomiolisis es multifactorial e incluye obstrucción tubular, vasoconstricción y daño oxidativo. El tratamiento principal de la IRA por rabdomiolisis es la hidratación, forzar la diuresis y evitar los fármacos nefrotóxicos. Cuando el daño es lo suficientemente grave para causar uremia, acidosis metabólica, hiperpotasemia y sobrecarga de volumen se debe recurrir a la terapia de reemplazo renal. Aunque la regla es que se recupere la función renal, estos pacientes tienen mayor riesgo futuro de desarrollar enfermedad renal crónica.

Biografía del autor/a

John Fredy Nieto-Ríos, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín.
Nefrólogo
Juliana Vega-Miranda, Hospital Pablo Tobón Uribe, Medellín.
Médica Internista
Lina María Serna-Higuita, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín.
Nefróloga Pediatra

Citas

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Publicado
2016-03-08
Sección
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