Trasplante renal en pacientes con infección por el virus de la inmunodeficiencia humana:

revisión de la literatura

  • John Fredy Nieto-Ríos Universidad de Antioquia
  • Natalia Rodríguez-Botero Universidad Pontificia Bolivariana
  • Arbey Aristizábal-Alzate Hospital Pablo Tobón Uribe
  • Gustavo Adolfo Zuluaga-Valencia Hospital Pablo Tobón Uribe
  • Isabel Cristina Ramírez-Sánchez Universidad de Antioquia
  • Lina María Serna-Higuita Universidad Eberhard Karls
Palabras clave: Insuficiencia Renal Crónica, Síndrome de Inmunodeficiencia Adquirida, Trasplante de Riñón, VIH

Resumen

El trasplante renal es el tratamiento de elección en la enfermedad renal crónica terminal porque mejora la calidad de vida y la supervivencia de los pacientes al compararlo con la diálisis. Sin embargo, para mantener un injerto funcional y evitar el rechazo es necesario el uso de inmunosupresión potente durante toda la vida del injerto, lo cual puede tener como complicaciones una mayor susceptibilidad a presentar infecciones, desarrollo de cáncer, alteraciones metabólicas y problemas cardiovasculares. Los pacientes infectados con el virus de la inmunodeficiencia humana tienen alto riesgo de desarrollar enfermedad renal crónica terminal por múltiples causas. En el siglo pasado, el trasplante renal se consideraba contraindicado para estos pacientes. No obstante, hoy en día el trasplante renal se considera una opción terapéutica para pacientes adecuadamente seleccionados y con protocolos de manejo bien establecidos. Reportándose supervivencia reportadas del injerto y del paciente a tres años de 88,2 % y 82,6 % respectivamente. Este artículo de revisión tiene como objetivo revisar la experiencia mundial existente en el manejo de los pacientes trasplantados renal con infección por VIH.

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Biografía del autor/a

John Fredy Nieto-Ríos, Universidad de Antioquia

Departamento de Nefrología y Trasplante Renal Hospital Pablo Tobón Uribe. Medellín Colombia. Departamento de Medicina Interna, Facultad de Medicina, Universidad de Antioquia. Medellín Colombia.

Natalia Rodríguez-Botero, Universidad Pontificia Bolivariana

 Departamento de Medicina Interna, Facultad de Medicina, Universidad Pontificia Bolivariana. Medellín Colombia.

Arbey Aristizábal-Alzate, Hospital Pablo Tobón Uribe

Departamento de Nefrología y Trasplante Renal Hospital Pablo Tobón Uribe. Medellín Colombia.

Gustavo Adolfo Zuluaga-Valencia, Hospital Pablo Tobón Uribe

Departamento de Nefrología y Trasplante Renal Hospital Pablo Tobón Uribe. Medellín Colombia.

Isabel Cristina Ramírez-Sánchez, Universidad de Antioquia

Departamento de Nefrología y Trasplante Renal Hospital Pablo Tobón Uribe. Medellín Colombia.  Departamento de Medicina Interna, Facultad de Medicina, Universidad de Antioquia. Medellín Colombia.

Lina María Serna-Higuita , Universidad Eberhard Karls

Eberhard Karls University, Instituto de epidemiología clínica y biometría aplicada. Tuebingen, Alemania.

Citas

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Publicado
2021-08-20
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Nieto-Ríos JF, Rodríguez-Botero N, Aristizábal-Alzate A, Zuluaga-Valencia GA, Ramírez-Sánchez IC, Serna-Higuita LM. Trasplante renal en pacientes con infección por el virus de la inmunodeficiencia humana: . Iatreia [Internet]. 20 de agosto de 2021 [citado 17 de septiembre de 2021];1(1). Disponible en: https://revistas.udea.edu.co/index.php/iatreia/article/view/346495
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