Therapeutic compliance in asthma: Is it a problem of great magnitude?

Authors

  • Arnaldo Ándrés Palomino-Rodríguez University of Antioquia
  • Olga Lucía Morales-Múnera University of Antioquia
  • Javier Orlando Contreras-Ortiz University of Antioquia
  • Olga Francisca Salazar-Blanco University of Antioquia

DOI:

https://doi.org/10.17533/udea.iatreia.v28n4a05

Keywords:

asthma, drug therapy, patient compliance

Abstract

Worldwide, asthma is the most common chronic disease of the lower respiratory tract in children, and, as a public health problem, it may affect people of all ages. Its control involves not only the recognition and diagnosis of the disease, but also the specific treatment and compliance to it. The latter is defined as the reasonable understanding by the patient of the need for treatment and its different possibilities, followed by appropriate actions. It has also been defined as the degree of cooperation and agreement between the physician and the patient concerning the therapeutic regimen, characterized by the patient’s understanding of and adherence to the scheme, including adequate medical patient communication. In developed countries adherence to treatment of asthma patients can be as low as 50 %, and in developing countries it may be even lower. Factors that influence therapeutic compliance in asthma depend on the patient, the physician, the relationship between them, the prescribed treatment, the patient-pharmacist, and the physician-pharmacist relationships, the structure of the health system, the community and the family.

|Abstract
= 653 veces | PDF (ESPAÑOL (ESPAÑA))
= 236 veces|

Downloads

Download data is not yet available.

Author Biographies

Arnaldo Ándrés Palomino-Rodríguez, University of Antioquia

Resident of Pediatrics, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia.

Olga Lucía Morales-Múnera, University of Antioquia

Pediatric Pulmonologist, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia.

Javier Orlando Contreras-Ortiz, University of Antioquia

Pediatrician, Master in Clinical Sciences, Faculty of Medicine, University of Antioquia, Medellín, Colombia.

Olga Francisca Salazar-Blanco, University of Antioquia

Pediatrician, Professor, Faculty of Medicine, University of Antioquia, Medellín, Colombia. Edusalud and Pediaciencia Research Groups.

References

(1.) Papadopoulos NG, Arakawa H, Carlsen KH, Custovic A, Gern J, Lemanske R, et al. International consensus on (ICON) pediatric asthma. Allergy. 2012 Aug;67(8):976-97.

(2.) Bender B, Milgrom H, Rand C. Nonadherence in asthmatic patients: is there a solution to the problem? Ann Allergy Asthma Immunol. 1997 Sep;79(3):177-85.

(3.) Milgrom H, Bender B, Ackerson L, Bowry P, Smith B, Rand C. Noncompliance and treatment failure in children with asthma. J Allergy Clin Immunol. 1996 Dec;98(6 Pt 1):1051-7.

(4.) Apter AJ, Reisine ST, Affleck G, Barrows E, ZuWallack RL. Adherence with twice-daily dosing of inhaled steroids. Socioeconomic and health-belief differences. Am J Respir Crit Care Med. 1998 Jun;157(6 Pt 1):1810-7.

(5.) Balkissoon R. Asthma overview. Prim Care. 2008 Mar;35(1):41-60.

(6.) Yu IT, Wong TW, Li W. Using child reported respiratory symptoms to diagnose asthma in the community. Arch Dis Child. 2004 Jun;89(6):544-8.

(7.) Masoli M, Fabian D, Holt S, Beasley R; Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy. 2004 May;59(5):469-78.

(8.) Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. Update 2012 [Internet]. [cited 2015 Ene 12]. Available from: http://www.ginasthma.org/local/uploads/files/GINA_Report_March13_1.pdf

(9.) Kupczyk M, Haahtela T, Cruz AA, Kuna P. Reduction of asthma burden is possible through National Asthma Plans. Allergy. 2010 Apr;65(4):415-9.

(10.) Asociación Colombiana de Neumología Pediátrica. Guía de práctica clínica (GPC) para el diagnóstico, atención integral y seguimiento de niños y niñas con diagnóstico de asma. Sistema General de Seguridad Social en Salud – Colombia. Guía Completa2013 [Internet]. [consultado 2014 Dic 2]. Disponible en: http://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/INEC/IETS/GPC_Comp_Asma.pdf

(11.) Krishnan JA, Bender BG, Wamboldt FS, Szefler SJ, Adkinson NF Jr, Zeiger RS, et al. Adherence to inhaled corticosteroids: an ancillary study of the Childhood Asthma Management Program clinical trial. J Allergy Clin Immunol. 2012 Jan;129(1):112-8.

(12.) Myers TR. Guidelines for asthma management: a review and comparison of 5 current guidelines. Respir Care. 2008 Jun;53(6):751-67.

(13.) Orero González A. Incumplimiento terapéutico en la enfermedad asmática. Barcelona: Grupo Ars XXI; 2005.

(14.) Bender BG, Rand C. Medication non-adherence and asthma treatment cost. Curr Opin Allergy Clin Immunol. 2004 Jun;4(3):191-5.

(15.) Haynes RB, McDonald H, Garg AX, Montague P. Interventions for helping patients to follow prescriptions for medications. Cochrane Database Syst Rev. 2002;(2):CD000011.

(16.) Cochrane MG, Bala MV, Downs KE, Mauskopf J, Ben-Joseph RH. Inhaled corticosteroids for asthma therapy: patient compliance, devices, and inhalation technique. Chest. 2000 Feb;117(2):542-50.

(17.) Horne R, Weinman J. Self-regulation and self-management in asthma: exploring the role of illness perceptions and treatments beliefs in explaining non-adherence to preventer medication. Psychol Health 2002;17(1):17-32.

(18.) Mahler C, Hermann K, Horne R, Ludt S, Haefeli WE, Szecsenyi J, et al. Assessing reported adherence to pharmacological treatment recommendations. Translation and evaluation of the Medication Adherence Report Scale (MARS) in Germany. J Eval Clin Pract. 2010 Jun;16(3):574-9.

(19.) López Viña A. Actitudes para fomentar el cumplimiento terapéutico en el asma. Arch Bronconeumol. 2005 Jun;41(6):334-40.

(20.) Berg JS, Dischler J, Wagner DJ, Raia JJ, Palmer-Shevlin N. Medication compliance: a healthcare problem. Ann Pharmacother. 1993 Sep;27(9 Suppl):S1-24.

(21.) Márquez Contreras E. Métodos de medida del cumplimiento terapéutico. Cumplimiento terapéutico en la HTA. Actualizaciones. 2004 Abr;1(1):5-6.

(22.) Mora PA, Berkowitz A, Contrada RJ, Wisnives-ky J, Horne R, Leventhal H, et al. Factor structure and longitudinal invariance of the Medical Adherence Report Scale-Asthma. Psychol Health. 2011 Jun;26(6):713-27.

(23.) Cochrane GM, Horne R, Chanez P. Compliance in asthma. Respir Med. 1999 Nov;93(11):763-9.

(24.) Home R. Adherence to medication: a review of existing research. In: Midence K, Myers L, editors. Adherence to treatment in medical conditions. London: Harwood Academic; 1998. p. 285-310.

(25.) Cohen JL, Mann DM, Wisnivesky JP, Home R, Leventhal H, Musumeci-Szabó TJ, et al. Assessing the validity of self-reported medication adherence among innercity asthmatic adults: the Medication Adherence Report Scale for Asthma. Ann Allergy Asthma Immunol. 2009 Oct;103(4):325-31.

(26.) Rand CS, Wise RA. Measuring adherence to asthma medication regimens. Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 2):S69-76.

(27.) Martín Alfonso L. Repercusiones para la salud pública de la adherencia terapéutica deficiente. RCSP. 2006 Jul-Sep;32(3).

(28.) Organización Mundial de la Salud. Adherencia a los tratamientos a largo plazo: Pruebas para la acción [Internet]. [consultado 2014 Nov 6]. Disponible en: http://www.paho.org/Spanish/AD/DPC/NC/adherencia-largo-plazo.pdf

(29.) Bauman LJ, Wright E, Leickly FE, Crain E, Kruszon-Moran D, Wade SL, et al. Relationship of adherence to pediatric asthma morbidity among inner-city children. Pediatrics. 2002 Jul;110(1 Pt 1):e6.

(30.) World Health Organization. How does poor adheren-ce affect policy-makers and health managers? Sabate E, editor. In: Adherence to long-term therapies: evi-dence for action. Geneva: World Health Organiza-tion; 2003. p. 38-42.

(31.) Dunbar-Jacob J, Erlen JA, Schlenk EA, Ryan CM, Se-reika SM, Doswell WM. Adherence in chronic disease. Annu Rev Nurs Res. 2000;18:48-90.32. Dunbar-Jacob J, Mortimer-Stephens MK. Treatment adherence in chronic disease. J Clin Epidemiol. 2001 Dec;54 Suppl 1:S57-60.

(33.) Reid D, Abramson M, Raven J, Walters HE. Manage-ment and treatment perceptions among young adults with asthma in Melbourne: the Australian experience from the European Community Respiratory Health Survey. Respirology. 2000 Sep;5(3):281-7.

(34.) Cerveri I, Locatelli F, Zoia MC, Corsico A, Accordini S, de Marco R. International variations in asthma treatment compliance: the results of the European Community Respiratory Health Survey (ECRHS). Eur Respir J. 1999 Aug;14(2):288-94.

(35.) Bender B, Milgrom H, Rand C. Nonadherence in asthmatic patients: is there a solution to the problem? Ann Allergy Asthma Immunol. 1997 Sep;79(3):177-85.

(36.) Duncan K. Asthma measure indices: utility, collectability and applicability to practice. In: Pearson MG, Bucknall CE. Measuring clinical outcomes in asthma. London: Royal College of Physicians; 1999. p. 23-6.

(37.) Dekker FW, Dieleman FE, Kaptein AA, Mulder JD. Compliance with pulmonary medication in general practice. Eur Respir J. 1993 Jun;6(6):886-90.

(38.) Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996 Aug;348(9024):383-6. Erratum in: Lancet 1997 Apr 19;349(9059):1180.

(39.) Chambers CV, Markson L, Diamond JJ, Lasch L, Berger M. Health beliefs and compliance with inhaled corticosteroids by asthmatic patients in primary care practices. Respir Med. 1999 Feb;93(2):88-94.

(40.) Menckeberg TT, Bouvy ML, Bracke M, Kaptein AA, Leufkens HG, Raaijmakers JA, et al. Beliefs about medicines predict refill adherence to inhaled corticosteroids. J Psychosom Res. 2008 Jan;64(1):47-54.

(41.) Bender BG, Iklé DN, DuHamel T, Tinkelman D. Retention of asthmatic patients in a longitudinal clinical trial. J Allergy Clin Immunol. 1997 Feb;99(2):197-203.

(42.) Getahun D, Demissie K, Rhoads GG. Recent trends in asthma hospitalization and mortality in the United States. J Asthma. 2005 Jun;42(5):373-8.

(43.) Grant EN, Lyttle CS, Weiss KB. The relation of socioeconomic factors and racial/ethnic differences in US asthma mortality. Am J Public Health. 2000 Dec;90(12):1923-5.

(44.) Kruse LK, Deshpande S, Vezina M. Disparities in asthma hospitalizations among children seen in the emergency department. J Asthma. 2007 Dec;44(10):833-7.

(45.) Lieu TA, Lozano P, Finkelstein JA, Chi FW, Jensvold NG, Capra AM, et al. Racial/ethnic variation in asthma status and management practices among children in managed medicaid. Pediatrics. 2002 May;109(5):857-65.

(46.) Rohan J, Drotar D, McNally K, Schluchter M, Riekert K, Vavrek P, et al. Adherence to pediatric asthma treatment in economically disadvantaged African-American children and adolescents: an application of growth curve analysis. J Pediatr Psychol. 2010 May;35(4):394-404.

(47.) Wahl C, Gregoire JP, Teo K, Beaulieu M, Labelle S, Leduc B, et al. Concordance, compliance and adherence in healthcare: closing gaps and improving outcomes. Healthc Q. 2005;8(1):65-70.

(48.) Williams LK, Peterson EL, Wells K, Ahmedani BK, Kumar R, Burchard EG, et al. Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. J Allergy Clin Immunol. 2011 Dec;128(6):1185-1191.e2.

(49.) MacCochrane, G. “Compliance and outcomes in patients with asthma.” Drugs 52.6 (1996): 12-19.

(50. ) Bukstein DA, Murphy KR, Katz LM, Ramachandran S, Doyle JJ, Stern LS. Outcomes among a young population of pediatric asthma patients using controller therapies: Results from a retrospective database analysis. Pediatr Asthma Allergy Immunol. 2007 Dec;20(4):211-22.

Published

2015-09-22

How to Cite

1.
Palomino-Rodríguez A Ándrés, Morales-Múnera OL, Contreras-Ortiz JO, Salazar-Blanco OF. Therapeutic compliance in asthma: Is it a problem of great magnitude?. Iatreia [Internet]. 2015 Sep. 22 [cited 2026 Mar. 3];28(4):400-9. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/19989

Issue

Section

Review articles

Most read articles by the same author(s)