Mid-line destructive syndrome secondary to infection by paracoccidioides sp. A case report

Authors

DOI:

https://doi.org/10.17533/udea.iatreia.160

Keywords:

Invasive Fungal Diseases , Mycoses , Paracoccidioidomycosis

Abstract

Midline destructive disease is a group of severe and destructive inflammatory and tumor diseases of the midface area, among which paracoccidioidomycosis is one of the main etiologies in tropical countries.

Paracoccidioidomycosis is an endemic mycosis caused by fungi of the genus Paracoccidioides. Its blastoconidia form favors hematogenous spread, affecting various tissues such as adrenal glands,  eticulo-endothelial tissue, or oral mucosa, where it can manifest as a  estructive midline syndrome. We present a case of paracoccidioidomycosis with affection in the oral cavity, which debuted as a chronic midline destructive disease with sever airway compromise that required surgical treatment for the risk of obstruction of the airway.
The patient received systemic treatment with good response.

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Author Biographies

Sebastián Barrera-Escobar, Universidad de Antioquia.

Internal Medicine Resident, School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Manuela Hurtado-González, Universidad de Antioquia

Resident of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Universidad de Antioquia, Medellin, Colombia.

Gustavo Vanegas-Ramírez, Universidad de Antioquia.

Physician, specialist in Otorhinolaryngology, IPS Universitaria Clínica León XIII, Medellín, Colombia.
Professor, Specialization in Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Universidad de Antioquia, Medellin, Colombia.

Juan Pablo Villa-Franco, IPS Universitaria Clínica León XIII

Internist specialized in infectious diseases, IPS Universitaria Clínica León XIII, Medellín, Colombia.

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Published

2022-07-01

How to Cite

1.
Barrera-Escobar S, Hurtado-González M, Vanegas-Ramírez G, Villa-Franco JP. Mid-line destructive syndrome secondary to infection by paracoccidioides sp. A case report. Iatreia [Internet]. 2022 Jul. 1 [cited 2025 Feb. 5];35(3):361-7. Available from: https://revistas.udea.edu.co/index.php/iatreia/article/view/347335

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Case reports

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